Salmonella effector SpvB aggravates dysregulation of systemic iron metabolism via modulating the hepcidin−ferroportin axis

The Discovery of the Iron-Regulatory Hormone Hepcidin

(2019) Tomas Ganz   CLINICAL CHEMISTRY

Salmonella effector SpvB interferes with intracellular iron homeostasis via regulation of transcription factor NRF2

(2019) Sidi Yang et al.   FASEB JOURNAL

Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages

(2018) Xiumei Che et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Salmonella epidemiology: A whirlwind of change

(2018) John M. Besser   FOOD MICROBIOLOGY

Innate Nutritional Immunity

(2018) Gabriel Núñez et al.   JOURNAL OF IMMUNOLOGY

Triggering Receptor Expressed on Myeloid Cells-1 Signaling: Protective and Pathogenic Roles on Streptococcal Toxic-Shock-Like Syndrome Caused by Streptococcus suis

(2018) Li Han et al.   Frontiers in Immunology

Dysregulated iron metabolism in polycythemia vera: etiology and consequences

(2018) Yelena Z. Ginzburg et al.   LEUKEMIA

Liver iron sensing and body iron homeostasis

(2018) Chia-Yu Wang et al.   BLOOD

The innate immune receptor TREM-1 promotes liver injury and fibrosis

(2018) Anh Thu Nguyen-Lefebvre et al.   JOURNAL OF CLINICAL INVESTIGATION

Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain

(2017) Fa-Li Zhang et al.   Frontiers in Molecular Neuroscience

Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection

(2017) Alexandra Willemetz et al.   Frontiers in Immunology

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

(2016) Alexander R. Bogdan et al.   TRENDS IN BIOCHEMICAL SCIENCES

A novel contribution of spvB to pathogenesis of Salmonella Typhimurium by inhibiting autophagy in host cells

(2016) Yuanyuan Chu et al.   Oncotarget

Alterations in the iron homeostasis network: A driving force for macrophage-mediated hepatitis C virus persistency

(2016) Pelagia Foka et al.   Virulence

Hepcidin: regulation of the master iron regulator

(2015) Gautam Rishi et al.   BIOSCIENCE REPORTS

Commensal Bacteria-induced Interleukin 1β (IL-1β) Secreted by Macrophages Up-regulates Hepcidin Expression in Hepatocytes by Activating the Bone Morphogenetic Protein Signaling Pathway

(2015) Nanda Kumar N. Shanmugam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli

(2015) D. Houamel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The iron-regulatory hormone hepcidin: A possible therapeutic target?

(2015) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Hepcidin1 Knockout Mice Display Defects in Bone Microarchitecture and Changes of Bone Formation Markers

(2014) Guang Si Shen et al.   CALCIFIED TISSUE INTERNATIONAL

Iron ERRs with Salmonella

(2014) Ferric C. Fang et al.   Cell Host & Microbe

TREM-1 Promotes Survival during Klebsiella pneumoniae Liver Abscess in Mice

(2014) Yi-Tsung Lin et al.   INFECTION AND IMMUNITY

Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis

(2014) Don-Kyu Kim et al.   NATURE MEDICINE

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Salmonella enterica Serovar Typhimurium Skills To Succeed in the Host: Virulence and Regulation

(2013) A. Fabrega et al.   CLINICAL MICROBIOLOGY REVIEWS

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppression of Hepcidin Expression and Iron Overload Mediate Salmonella Susceptibility in Ankyrin 1 ENU-Induced Mutant

(2013) Kyoko E. Yuki et al.   PLoS One

Curcumin mediated epigenetic modulation inhibits TREM-1 expression in response to lipopolysaccharide

(2012) Zhihong Yuan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Role of the spv Genes in Salmonella Pathogenesis

(2011) Donald G. Guiney et al.   Frontiers in Microbiology

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Identification ofSalmonellaSPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice

(2008) Sara H. Browne et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells

(2007) T Chaston et al.   GUT