Highly efficient magnetic labelling allows MRI tracking of the homing of stem cell‐derived extracellular vesicles following systemic delivery

Endothelial progenitor cells-secreted extracellular vesicles containing microRNA-93-5p confer protection against sepsis-induced acute kidney injury via the KDM6B/H3K27me3/TNF-α axis

(2020) Zhonghua He et al.   EXPERIMENTAL CELL RESEARCH

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors

(2019) Lynn Yap et al.   Cell Reports

Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells

(2019) Senquan Liu et al.   STEM CELLS

Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders

(2019) Nisim Perets et al.   NANO LETTERS

Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury

(2019) Lin-Li Lv et al.   CELL DEATH AND DIFFERENTIATION

Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention

(2019) Sixiang Shi et al.   BIOCONJUGATE CHEMISTRY

Development and MPI tracking of novel hypoxia-targeted theranostic exosomes

(2018) Kyung Oh Jung et al.   BIOMATERIALS

Triazoles as T2-exchange MRI contrast agents for the detection of nitrilase activity

(2018) Jia Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Secret Life of Exosomes

(2018) Eduardo Marbán   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CEST MRI of sepsis-induced acute kidney injury

(2018) Jing Liu et al.   NMR IN BIOMEDICINE

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells

(2018) Bohao Liu et al.   Nature Biomedical Engineering

Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

(2018) Travis J. Antes et al.   JOURNAL OF NANOBIOTECHNOLOGY

Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents

(2018) Rajendran JC Bose et al.   ACS Nano

Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics

(2017) Chonlada Charoenviriyakul et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmacokinetics of Exosomes—An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics

(2017) Masaki Morishita et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

Extracellular vesicles in renal disease

(2017) Diana Karpman et al.   Nature Reviews Nephrology

Nerolidol Protects Against LPS-induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Signaling

(2017) Lu Zhang et al.   PHYTOTHERAPY RESEARCH

A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice

(2017) Prakash Gangadaran et al.   Oncotarget

The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury

(2017) Andrea Ranghino et al.   Stem Cell Research & Therapy

Induced Pluripotent Stem Cell (iPSC)–Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair Than iPSCs

(2017) Marta Adamiak et al.   CIRCULATION RESEARCH

Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy

(2016) Hongzhao Qi et al.   ACS Nano

Exosomes and Cardiovascular Protection

(2016) Sean M. Davidson et al.   CARDIOVASCULAR DRUGS AND THERAPY

Transfer of microRNA-486-5p from human endothelial colony forming cell–derived exosomes reduces ischemic kidney injury

(2016) Jose L. Viñas et al.   KIDNEY INTERNATIONAL

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Sepsis-Induced Acute Kidney Injury

(2015) Johan Mårtensson et al.   CRITICAL CARE CLINICS

AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs

(2015) F. Collino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications

(2015) Sweta Rani et al.   MOLECULAR THERAPY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

In vivomagnetic resonance imaging of iron oxide-labeled, intravenous-injected mesenchymal stem cells in kidneys of rabbits with acute ischemic kidney injury: detection and monitoring at 1.5 T

(2015) Ruiping Zhang et al.   RENAL FAILURE

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using 99mTc-HMPAO

(2015) Do Won Hwang et al.   Scientific Reports

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging

(2014) CRISTINA GRANGE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Magnetic resonance imaging of melanoma exosomes in lymph nodes

(2014) Lingzhi Hu et al.   MAGNETIC RESONANCE IN MEDICINE

Maximizing exosome colloidal stability following electroporation

(2013) Joshua L. Hood et al.   ANALYTICAL BIOCHEMISTRY

Induced Pluripotent Stem Cells without c-Myc Attenuate Acute Kidney Injury via Downregulating the Signaling of Oxidative Stress and Inflammation in Ischemia–Reperfusion Rats

(2013) Pei-Ying Lee et al.   CELL TRANSPLANTATION

Improved MRIR2* relaxometry of iron-loaded liver with noise correction

(2013) Yanqiu Feng et al.   MAGNETIC RESONANCE IN MEDICINE

Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

(2013) Ying Zhou et al.   Stem Cell Research & Therapy

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Microvesicles Derived from Mesenchymal Stem Cells Enhance Survival in a Lethal Model of Acute Kidney Injury

(2012) Stefania Bruno et al.   PLoS One

Bone Marrow-Derived Mesenchymal Stem Cells Repaired but Did Not Prevent Gentamicin-Induced Acute Kidney Injury through Paracrine Effects in Rats

(2012) Luciana A. Reis et al.   PLoS One

Improving the Magnetic Resonance Imaging Contrast and Detection Methods with Engineered Magnetic Nanoparticles

(2012) Jing Huang et al.   Theranostics

Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy

(2012) Serena Rubina Baglio et al.   Frontiers in Physiology

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

(2011) Bin-Kuan Chou et al.   CELL RESEARCH

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury

(2009) S. Bruno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy

(2008) Massimiliano Gnecchi et al.   CIRCULATION RESEARCH

Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing

(2008) Liwen Chen et al.   PLoS One