Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells

Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen

(2018) Takahiro USHIGUSA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Exosomes derived from tumor cells genetically modified to express Mycobacterium tuberculosis antigen: a novel vaccine for cancer therapy

(2016) Yoshiyuki Koyama et al.   BIOTECHNOLOGY LETTERS

Exosomes and tumor-mediated immune suppression

(2016) Theresa L. Whiteside   JOURNAL OF CLINICAL INVESTIGATION

Highly Effective Non-Viral Antitumor Gene Therapy System Comprised of Biocompatible Small Plasmid Complex Particles Consisting of pDNA, Anionic Polysaccharide, and Fully Deprotected Linear Polyethylenimine

(2015) Yoshiyuki Koyama et al.   Pharmaceutics

Novel Antitumor Strategy Utilizing a Plasmid Expressing a Mycobacterium tuberculosis Antigen as a “Danger Signal” to Block Immune Escape of Tumor Cells

(2015) Yoshiyuki Koyama et al.   Pharmaceutics

Acquired and intrinsic resistance in cancer immunotherapy

(2014) Sander Kelderman et al.   Molecular Oncology

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preparation of Calcium Phosphate Nanocapsule Including Deoxyribonucleic Acid–Polyethyleneimine–Hyaluronic Acid Ternary Complex for Durable Gene Delivery

(2013) Tomoko Ito et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

More efficient induction of antitumor T cell immunity by exosomes from CD40L gene-modified lung tumor cells

(2013) JIAOLI WANG et al.   Molecular Medicine Reports

Melanoma cell-derived exosomes alter macrophage and dendritic cell functions in vitro

(2012) Annamaria Marton et al.   IMMUNOLOGY LETTERS

Exosome-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma

(2011) Ning Bu et al.   JOURNAL OF NEURO-ONCOLOGY

DNA/polyethyleneimine/hyaluronic acid small complex particles and tumor suppression in mice

(2010) Tomoko Ito et al.   BIOMATERIALS

Proteomic and immunologic analyses of brain tumor exosomes

(2008) Michael W. Graner et al.   FASEB JOURNAL

Specificity in cancer immunotherapy

(2008) Andrea Schietinger et al.   SEMINARS IN IMMUNOLOGY