Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling

Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling

(2020) Manish Kumar et al.   Nature Communications

Dietary Fructose Alters the Composition, Localization, and Metabolism of Gut Microbiota in Association With Worsening Colitis

(2020) David C. Montrose et al.   Cellular and Molecular Gastroenterology and Hepatology

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

Implications of the Westernized Diet in the Onset and Progression of IBD

(2019) Fernando Rizzello et al.   Nutrients

Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection

(2019) Martinna Bertolini et al.   PLoS Pathogens

Diet Rich in Animal Protein Promotes Pro-inflammatory Macrophage Response and Exacerbates Colitis in Mice

(2019) Klara Kostovcikova et al.   Frontiers in Immunology

Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

(2019) Kaitlyn Oliphant et al.   Microbiome

Additional Candida albicans administration enhances the severity of dextran sulfate solution induced colitis mouse model through leaky gut-enhanced systemic inflammation and gut-dysbiosis but attenuated by Lactobacillus rhamnosus L34

(2019) Wimonrat Panpetch et al.   Gut Microbes

Western Diet and the Immune System: An Inflammatory Connection

(2019) Anette Christ et al.   IMMUNITY

A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice

(2019) Michael Laffin et al.   Scientific Reports

The locus coeruleus neurotoxin, DSP4, and/or a high sugar diet induce behavioral and biochemical alterations in wild-type mice consistent with Alzheimers related pathology

(2018) Pooja Choudhary et al.   METABOLIC BRAIN DISEASE

High-Glucose or -Fructose Diet Cause Changes of the Gut Microbiota and Metabolic Disorders in Mice without Body Weight Change

(2018) Moon Do et al.   Nutrients

Enterobacteriaceae are essential for the modulation of colitis severity by fungi

(2018) Bruno Sovran et al.   Microbiome

A high‑fructose diet induces epithelial barrier dysfunction and exacerbates the severity of dextran sulfate sodium‑induced colitis

(2018) Katsuto Kawabata et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Maternal intake of sugar during pregnancy and childhood respiratory and atopic outcomes

(2017) Annabelle Bédard et al.   EUROPEAN RESPIRATORY JOURNAL

Clinical importance of IL-22 cascade in IBD

(2017) Atsushi Mizoguchi et al.   JOURNAL OF GASTROENTEROLOGY

NMRProcFlow: a graphical and interactive tool dedicated to 1D spectra processing for NMR-based metabolomics

(2017) D. Jacob et al.   Metabolomics

Akkermansia muciniphila and its role in regulating host functions

(2017) Muriel Derrien et al.   MICROBIAL PATHOGENESIS

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

(2017) Lukas Bajer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Adherence to Mediterranean Diet and Risk of Cancer: An Updated Systematic Review and Meta-Analysis

(2017) Lukas Schwingshackl et al.   Nutrients

Sugar intake from sweet food and beverages, common mental disorder and depression: prospective findings from the Whitehall II study

(2017) Anika Knüppel et al.   Scientific Reports

NLRP6 Protects Il10 −/− Mice from Colitis by Limiting Colonization of Akkermansia muciniphila

(2017) Sergey S. Seregin et al.   Cell Reports

Diet, Environments, and Gut Microbiota. A Preliminary Investigation in Children Living in Rural and Urban Burkina Faso and Italy

(2017) Carlotta De Filippo et al.   Frontiers in Microbiology

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

(2017) Patrice D. Cani et al.   Frontiers in Microbiology

Saturated fatty acids trigger TLR4-mediated inflammatory response

(2016) D.M. Rocha et al.   ATHEROSCLEROSIS

Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe

(2016) Antoine Racine et al.   INFLAMMATORY BOWEL DISEASES

A pathogenic role for T cell–derived IL-22BP in inflammatory bowel disease

(2016) Penelope Pelczar et al.   SCIENCE

Oscillospira : a Central, Enigmatic Component of the Human Gut Microbiota

(2016) Tom Konikoff et al.   TRENDS IN MICROBIOLOGY

Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation

(2016) Konrad Aden et al.   Cell Reports

Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes

(2016) Cheryn J. Couter et al.   Jove-Journal of Visualized Experiments

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

(2016) Allison Agus et al.   Scientific Reports

Low-grade inflammation, diet composition and health: current research evidence and its translation

(2015) Anne M. Minihane et al.   BRITISH JOURNAL OF NUTRITION

TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation

(2015) Licio A. Velloso et al.   ENDOCRINE REVIEWS

Carbohydrate Intake in the Etiology of Crohnʼs Disease and Ulcerative Colitis

(2014) Simon S. M. Chan et al.   INFLAMMATORY BOWEL DISEASES

Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn’s disease and healthy individuals

(2014) Jacob Tveiten Bjerrum et al.   Metabolomics

Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults

(2014) Quanhe Yang et al.   JAMA Internal Medicine

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Short exposure to a diet rich in both fat and sugar or sugar alone impairs place, but not object recognition memory in rats

(2013) Jessica E. Beilharz et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of “Western Diet” in Inflammatory Autoimmune Diseases

(2013) Arndt Manzel et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Topographic diversity of fungal and bacterial communities in human skin

(2013) Keisha Findley et al.   NATURE

Vitamin E prevents high-fat high-carbohydrates diet-induced memory impairment: The role of oxidative stress

(2013) Karem H. Alzoubi et al.   PHYSIOLOGY & BEHAVIOR

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Improved software detection and extraction of ITS1 and ITS2 from ribosomal ITS sequences of fungi and other eukaryotes for analysis of environmental sequencing data

(2013) Johan Bengtsson-Palme et al.   Methods in Ecology and Evolution

Bacteria, Colonic Fermentation, and Gastrointestinal Health

(2012) George T. Macfarlane et al.   JOURNAL OF AOAC INTERNATIONAL

Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies

(2012) Anna Klindworth et al.   NUCLEIC ACIDS RESEARCH

The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases

(2011) Helena Tlaskalová-Hogenová et al.   Cellular & Molecular Immunology

Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment

(2011) Zuzana Zakostelska et al.   PLoS One

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Negative regulation of Toll-like receptor signaling plays an essential role in homeostasis of the intestine

(2010) Amlan Biswas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Increased Fructose Intake as a Risk Factor For Dementia

(2010) B. C. M. Stephan et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Diet, gut microbiota and immune responses

(2010) Kendle M Maslowski et al.   NATURE IMMUNOLOGY

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A high fructose diet impairs spatial memory in male rats

(2009) A.P. Ross et al.   NEUROBIOLOGY OF LEARNING AND MEMORY