Role of HMGB1/TLR4 Axis in Ischemia/Reperfusion-Impaired Extracellular Glutamate Clearance in Primary Astrocytes

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

(2020) Philip Kitchen et al.   CELL

Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging

(2020) Mootaz M. Salman et al.   Frontiers in Bioengineering and Biotechnology

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release

(2019) Shaimaa Mahmoud et al.   Cells

The Role of High Mobility Group Box 1 in Ischemic Stroke

(2019) Yingze Ye et al.   Frontiers in Cellular Neuroscience

Disease modelling in human organoids

(2019) Madeline A. Lancaster et al.   Disease Models & Mechanisms

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

Glycyrrhizin mitigates radiation‐induced acute lung injury by inhibiting the HMGB1/TLR4 signalling pathway

(2019) Lei Zheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular Communication of a Dying Neuron in Stroke

(2018) Berta Puig et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Arctic ground squirrel resist peroxynitrite-mediated cell death in response to oxygen glucose deprivation

(2017) Saurav Bhowmick et al.   FREE RADICAL BIOLOGY AND MEDICINE

Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis, and glutamate efflux

(2017) Saurav Bhowmick et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 expression after oxygen-glucose deprivation and reoxygenation via TLR4 and NF-κB signaling in an IL-6-dependent manner

(2017) Lin Sun et al.   Journal of Neuroinflammation

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

(2017) Mootaz M. Salman et al.   Frontiers in Cellular Neuroscience

The dual role and therapeutic potential of high-mobility group box 1 in cancer

(2017) Si-Jia He et al.   Oncotarget

Hypothermia inhibits the propagation of acute ischemic injury by inhibiting HMGB1

(2016) Jung Ho Lee et al.   Molecular Brain

Stimulating ERK/PI3K/NFκB signaling pathways upon activation of mGluR2/3 restores OGD-induced impairment in glutamate clearance in astrocytes

(2013) Chia-Ho Lin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

HMGB1 in vascular diseases: Its role in vascular inflammation and atherosclerosis

(2012) A.W.S. de Souza et al.   AUTOIMMUNITY REVIEWS

Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion

(2012) Seung-Woo Kim et al.   NEUROBIOLOGY OF DISEASE

Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons

(2010) Jian Zou et al.   NEUROCHEMISTRY INTERNATIONAL

Increased High Mobility Group Box-1 Protein Levels are Associated With Impaired Cardiopulmonary and Echocardiographic Findings After Acute Myocardial Infarction

(2009) Plinio Cirillo et al.   JOURNAL OF CARDIAC FAILURE

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

Induction and subcellular localization of high-mobility group box–1 (HMGB1) in the postischemic rat brain

(2007) Jung-Bin Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH