Role of VapBC12 Toxin-Antitoxin Locus in Cholesterol-Induced Mycobacterial Persistence

Granulocytes act as a niche for Mycobacterium tuberculosis growth

(2020) Rustin R. Lovewell et al.   Mucosal Immunology

How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication

(2019) Wolfgang Eisenreich et al.   Frontiers in Cellular and Infection Microbiology

Publisher Correction: Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy

(2019) Qiyao Chai et al.   Nature Communications

Characterising resuscitation promoting factor fluorescent-fusions in mycobacteria

(2018) Iria Uhía et al.   BMC MICROBIOLOGY

System-Wide Analysis Unravels the Differential Regulation and In Vivo Essentiality of Virulence-Associated Proteins B and C Toxin-Antitoxin Systems of Mycobacterium tuberculosis

(2018) Sakshi Agarwal et al.   JOURNAL OF INFECTIOUS DISEASES

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

Quorum Sensing Extracellular Death Peptides Enhance the Endoribonucleolytic Activities of Mycobacterium tuberculosis MazF Toxins

(2018) Akanksha Nigam et al.   mBio

Distinct mechanisms coordinate transcription and translation under carbon and nitrogen starvation in Escherichia coli

(2018) Sukanya Iyer et al.   Nature Microbiology

Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria

(2018) Alexandra Sakatos et al.   Science Advances

Homologous VapC Toxins Inhibit Translation and Cell Growth by Sequence-Specific Cleavage of tRNA fMet

(2017) Lauren R. Walling et al.   JOURNAL OF BACTERIOLOGY

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Why so narrow: Distribution of anti-sense regulated, type I toxin-antitoxin systems compared with type II and type III systems

(2017) Dorien S. Coray et al.   RNA Biology

ATP-Dependent Persister Formation in Escherichia coli

(2017) Yue Shan et al.   mBio

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

VapCs of Mycobacterium tuberculosis cleave RNAs essential for translation

(2016) Kristoffer Winther et al.   NUCLEIC ACIDS RESEARCH

Separable roles forMycobacterium tuberculosisESX-3 effectors in iron acquisition and virulence

(2016) JoAnn M. Tufariello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure, Evolution, and Functions of Bacterial Type III Toxin-Antitoxin Systems

(2016) Nathalie Goeders et al.   Toxins

Tuberculosis

(2016) Madhukar Pai et al.   Nature Reviews Disease Primers

Persister formation in Staphylococcus aureus is associated with ATP depletion

(2016) Brian P. Conlon et al.   Nature Microbiology

Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase

(2015) Jonathan W. Cruz et al.   Nature Communications

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

(2015) Brian C. VanderVen et al.   PLoS Pathogens

Energy Metabolism and Drug Efflux in Mycobacterium tuberculosis

(2014) P. A. Black et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial persisters: formation, eradication, and experimental systems

(2014) Sophie Helaine et al.   TRENDS IN MICROBIOLOGY

Metabolism in Fungal Pathogenesis

(2014) I. V. Ene et al.   Cold Spring Harbor Perspectives in Medicine

Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress

(2013) Hsin-Yao Cheng et al.   ENVIRONMENTAL MICROBIOLOGY

A problem of persistence: still more questions than answers?

(2013) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Role of Oxidative Stress in Persister Tolerance

(2012) Yanxia Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting Persisters for Tuberculosis Control

(2012) Ying Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

(2011) David G. Russell   IMMUNOLOGICAL REVIEWS

Regulation of growth and death in Escherichia coli by toxin–antitoxin systems

(2011) Yoshihiro Yamaguchi et al.   NATURE REVIEWS MICROBIOLOGY

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

VapC Toxins from Mycobacterium tuberculosis Are Ribonucleases that Differentially Inhibit Growth and Are Neutralized by Cognate VapB Antitoxins

(2011) Bintou Ahmadou Ahidjo et al.   PLoS One

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Letting Sleeping dos Lie: Does Dormancy Play a Role in Tuberculosis?

(2010) Michael C. Chao et al.   Annual Review of Microbiology

Mycobacterium tuberculosis Wears What It Eats

(2010) David G. Russell et al.   Cell Host & Microbe

Metabolomics of Mycobacterium tuberculosis Reveals Compartmentalized Co-Catabolism of Carbon Substrates

(2010) Luiz Pedro S. de Carvalho et al.   CHEMISTRY & BIOLOGY

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array

(2010) V. L. Arcus et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The vapBC Operon from Mycobacterium smegmatis Is An Autoregulated Toxin–Antitoxin Module That Controls Growth via Inhibition of Translation

(2009) Jennifer Robson et al.   JOURNAL OF MOLECULAR BIOLOGY

The resuscitation-promoting factors ofMycobacterium tuberculosisare required for virulence and resuscitation from dormancy but are collectively dispensable for growthin vitro

(2009) Bavesh D. Kana et al.   MOLECULAR MICROBIOLOGY

Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis

(2009) Noel H. Smith et al.   NATURE REVIEWS MICROBIOLOGY

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

(2009) Holly R. Ramage et al.   PLoS Genetics

(p)ppGpp: Still Magical?

(2008) Katarzyna Potrykus et al.   Annual Review of Microbiology

The Extracellular Death Factor: Physiological and Genetic Factors Influencing Its Production and Response in Escherichia coli

(2008) I. Kolodkin-Gal et al.   JOURNAL OF BACTERIOLOGY

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

(2008) S. P. S. Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The case for hypervirulence through gene deletion in Mycobacterium tuberculosis

(2008) Annemieke M.C. ten Bokum et al.   TRENDS IN MICROBIOLOGY