CReVIS-Seq: A Highly Accurate and Multiplexable Method for Genome-wide Mapping of Lentiviral Integration Sites

CRISPR Diagnosis and Therapeutics with Single Base Pair Precision

(2019) Seung Hwan Lee et al.   TRENDS IN MOLECULAR MEDICINE

Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection

(2018) Heon Seok Kim et al.   GENOME RESEARCH

Clinical use of lentiviral vectors

(2018) Michael C. Milone et al.   LEUKEMIA

CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets

(2017) Shengdar Q Tsai et al.   NATURE METHODS

Identifying and retargeting transcriptional hot spots in the human genome

(2016) Joseph K. Cheng et al.   Biotechnology Journal

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

(2016) Daesik Kim et al.   GENOME RESEARCH

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the βA(T87Q)-GlobinGene

(2016) Olivier Negre et al.   HUMAN GENE THERAPY

Identifying and retargeting transcriptional hot spots in the human genome

(2016) Joseph K. Cheng et al.   Biotechnology Journal

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

(2014) S. Bae et al.   BIOINFORMATICS

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

(2014) S. Kim et al.   GENOME RESEARCH

Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy

(2013) A. Biffi et al.   SCIENCE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

(2011) A. Biffi et al.   BLOOD

Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia

(2011) Keshet Ronen et al.   MOLECULAR THERAPY

The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy

(2009) Eugenio Montini et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells

(2009) Gary P Wang et al.   MOLECULAR THERAPY

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

Mechanisms Governing Lentivirus Integration Site Selection

(2008) Angela Ciuffi   CURRENT GENE THERAPY

Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors

(2008) M. Bokhoven et al.   JOURNAL OF VIROLOGY