Governing transport principles for nanotherapeutic application in the brain

Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

(2020) Song Ih Ahn et al.   Nature Communications

Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles

(2020) Eugene P. Chung et al.   Pharmaceutics

Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Effect of Cell Sex on Uptake of Nanoparticles: The Overlooked Factor at the Nanobio Interface

(2018) Vahid Serpooshan et al.   ACS Nano

Super-Resolution Imaging of the Extracellular Space in Living Brain Tissue

(2018) Jan Tønnesen et al.   CELL

Crossing the blood-brain barrier with nanoparticles

(2018) Yiqun Zhou et al.   JOURNAL OF CONTROLLED RELEASE

G5G2.5 core-shell tecto-dendrimer specifically targets reactive glia in brain ischemia

(2018) Veronica Murta et al.   JOURNAL OF NEUROCHEMISTRY

Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

(2018) Yossef Alnasser et al.   MOLECULES

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

(2018) Humberto Mestre et al.   eLife

Effect of anesthetics on microglial activation and nanoparticle uptake: Implications for drug delivery in traumatic brain injury

(2017) Gokul Kannan et al.   JOURNAL OF CONTROLLED RELEASE

Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic–ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia

(2017) Christina L. Nemeth et al.   Nanomedicine-Nanotechnology Biology and Medicine

Uptake of silica nanoparticles in the brain and effects on neuronal differentiation using different in vitro models

(2017) Angélique D. Ducray et al.   Nanomedicine-Nanotechnology Biology and Medicine

The Glymphatic Pathway: Waste Removal from the CNS via Cerebrospinal Fluid Transport

(2017) Helene Benveniste et al.   NEUROSCIENTIST

Surface chemistry governs cellular tropism of nanoparticles in the brain

(2017) Eric Song et al.   Nature Communications

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

(2017) Alex J Smith et al.   eLife

Blood-Brain Glucose Transfer in Alzheimer’s disease: Effect of GLP-1 Analog Treatment

(2017) Michael Gejl et al.   Scientific Reports

High-content analysis of factors affecting gold nanoparticle uptake by neuronal and microglial cells in culture

(2016) A. Stojiljković et al.   Nanoscale

Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain

(2016) Antoine G. Godin et al.   Nature Nanotechnology

The Age of Cortical Neural Networks Affects Their Interactions with Magnetic Nanoparticles

(2016) Andy Tay et al.   Small

Systems-level thinking for nanoparticle-mediated therapeutic delivery to neurological diseases

(2016) Chad Curtis et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Strategies for transporting nanoparticles across the blood–brain barrier

(2016) Tian-Tian Zhang et al.   Biomaterials Science

Omega 3 Fatty Acids: Novel Neurotherapeutic Targets for Cognitive Dysfunction in Mood Disorders and Schizophrenia?

(2015) Christian Knochel et al.   Current Neuropharmacology

Intranasal delivery: circumventing the iron curtain to treat neurological disorders

(2015) Yongjun Jiang et al.   Expert Opinion on Drug Delivery

Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives?

(2015) Norman R. Saunders et al.   Frontiers in Neuroscience

Non-invasive delivery of stealth, brain-penetrating nanoparticles across the blood−brain barrier using MRI-guided focused ultrasound

(2014) Elizabeth Nance et al.   JOURNAL OF CONTROLLED RELEASE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

(2012) E. A. Nance et al.   Science Translational Medicine

Principles of strategic drug delivery to the brain (SDDB): Development of anorectic and orexigenic analogs of leptin

(2011) W.A. Banks et al.   PHYSIOLOGY & BEHAVIOR

Calcium diffusion enhanced after cleavage of negatively charged components of brain extracellular matrix by chondroitinase ABC

(2009) Sabina Hrabětová et al.   JOURNAL OF PHYSIOLOGY-LONDON