MeCP2 and Major Satellite Forward RNA Cooperate for Pericentric Heterochromatin Organization

Epigenetic Factors That Control Pericentric Heterochromatin Organization in Mammals

(2020) Salvatore Fioriniello et al.   Genes

Heterochromatin drives compartmentalization of inverted and conventional nuclei

(2019) Martin Falk et al.   NATURE

ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation

(2019) Domenico Marano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation

(2019) Xiangru Huo et al.   MOLECULAR CELL

MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

(2019) Alexia Martínez de Paz et al.   Epigenetics & Chromatin

Long non-coding RNA ChRO1 facilitates ATRX/DAXX-dependent H3.3 deposition for transcription-associated heterochromatin reorganization

(2018) Jinyoung Park et al.   NUCLEIC ACIDS RESEARCH

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

(2017) Rebekah Tillotson et al.   NATURE

Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation

(2017) Oscar Velazquez Camacho et al.   eLife

Characterization and dynamics of pericentromere-associated domains in mice

(2015) Patrick J. Wijchers et al.   GENOME RESEARCH

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

(2013) Matthew J Lyst et al.   NATURE NEUROSCIENCE

Chromatin context and ncRNA highlight targets of MeCP2 in brain

(2013) Scott S Maxwell et al.   RNA Biology

Heterochromatin Reorganization during Early Mouse Development Requires a Single-Stranded Noncoding Transcript

(2013) Miguel Casanova et al.   Cell Reports

Transcriptional Activation of Mouse Major Satellite Regions during Neuronal Differentiation

(2012) Yusuke Kishi et al.   CELL STRUCTURE AND FUNCTION

MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line

(2012) Bianca Bertulat et al.   PLoS One

Mutations in MECP2 exon 1 in classical rett patients disrupt MECP2_e1 transcription, but not transcription of MECP2_e2

(2011) Peter J. Gianakopoulos et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Long non-coding RNA modifies chromatin

(2011) Alka Saxena et al.   BIOESSAYS

Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes

(2011) Bredford Kerr et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

MeCP2 Rett mutations affect large scale chromatin organization

(2011) Noopur Agarwal et al.   HUMAN MOLECULAR GENETICS

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

(2011) Christèle Maison et al.   NATURE GENETICS

Heterochromatin maintenance and establishment: Lessons from the mouse pericentromere

(2011) Geneviève Almouzni et al.   Nucleus

A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development

(2010) Aline.V. Probst et al.   DEVELOPMENTAL CELL

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus

(2009) Shay Ben-Shachar et al.   HUMAN MOLECULAR GENETICS

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice

(2008) D. G.M. Jugloff et al.   HUMAN MOLECULAR GENETICS

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

(2008) A. Kumar et al.   JOURNAL OF CELL SCIENCE

MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG

(2008) Kok Lian Ho et al.   MOLECULAR CELL

Specific mutations in Methyl-CpG-Binding Protein 2 confer different severity in Rett syndrome

(2008) J. L. Neul et al.   NEUROLOGY

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE

High-Throughput Screening-Compatible Single-Step Protocol to Differentiate Embryonic Stem Cells in Neurons

(2008) Annalisa Fico et al.   STEM CELLS AND DEVELOPMENT