MiR‐22 modulates the expression of lipogenesis‐related genes and promotes hepatic steatosis in vitro

Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity by miR-181/SIRT1/PGC-1α/Nrf2 signaling pathway in human neuroblastoma SH-SY5Y cells: Implication for association between chlorpyrifos and Parkinson's

(2019) Meng-Wen Zhao et al.   ENVIRONMENTAL TOXICOLOGY

Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy

(2019) Alessandra Stacchiotti et al.   Cells

New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease

(2017) Mireia López-Riera et al.   Frontiers in Pharmacology

MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals

(2017) Benedetta Donati et al.   Scientific Reports

NAFLD and liver transplantation: Current burden and expected challenges

(2016) Raluca Pais et al.   JOURNAL OF HEPATOLOGY

MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1

(2015) J.-H. Lee et al.   CANCER RESEARCH

Correction: Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

(2015) Laura Bordone et al.   PLOS BIOLOGY

MiR-132 Inhibits Expression of SIRT1 and Induces Pro-inflammatory Processes of Vascular Endothelial Inflammation through Blockade of the SREBP-1c Metabolic Pathway

(2014) Liwei Zhang et al.   CARDIOVASCULAR DRUGS AND THERAPY

miR-22 inhibits proliferation and invasion in estrogen receptor α-positive endometrial endometrioid carcinomas cells

(2014) SHAORU LI et al.   Molecular Medicine Reports

MicroRNA-223 coordinates cholesterol homeostasis

(2014) Kasey C. Vickers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-22 in cardiac remodeling and disease

(2014) Zhan-Peng Huang et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Elevated microRNA-34a in obesity reduces NAD+levels and SIRT1 activity by directly targeting NAMPT

(2013) Sung-E Choi et al.   AGING CELL

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia

(2012) Kasey C. Vickers et al.   HEPATOLOGY

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

(2012) Shu-hao Hsu et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

(2012) Wei-Chih Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Upregulation of miR-22 Promotes Osteogenic Differentiation and Inhibits Adipogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells by Repressing HDAC6 Protein Expression

(2012) Shan Huang et al.   STEM CELLS AND DEVELOPMENT

Tumor Suppressor miR-22 Determines p53-Dependent Cellular Fate through Post-transcriptional Regulation of p21

(2011) N. Tsuchiya et al.   CANCER RESEARCH

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets

(2011) Deepti Ramachandran et al.   FEBS Journal

miR-22 represses cancer progression by inducing cellular senescence

(2011) Dan Xu et al.   JOURNAL OF CELL BIOLOGY

Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β

(2011) Nicole Schonrock et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Frequent Downregulation of miR-34 Family in Human Ovarian Cancers

(2010) D. C. Corney et al.   CLINICAL CANCER RESEARCH

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

(2010) Carolina Tarantino et al.   FASEB JOURNAL

An inhibitory effect of miR-22 on cell migration and invasion in ovarian cancer

(2010) Jun Li et al.   GYNECOLOGIC ONCOLOGY

Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22

(2010) J B Patel et al.   ONCOGENE

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells

(2008) Yasunori Fujita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA