Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
出版年份 2020 全文链接
标题
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
作者
关键词
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出版物
eLife
Volume 9, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2020-12-23
DOI
10.7554/elife.59073
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
- (2020) Julia Minderjahn et al. Nature Communications
- Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non–Small Cell Lung Carcinoma
- (2020) Shujie Song et al. MOLECULAR CANCER RESEARCH
- Re-assigning the histologic identities of COV434 and TOV-112D ovarian cancer cell lines
- (2020) Anthony N. Karnezis et al. GYNECOLOGIC ONCOLOGY
- CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary
- (2019) Yibo Xue et al. Nature Communications
- SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer
- (2019) Yibo Xue et al. Nature Communications
- The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting
- (2019) Joshua Pan et al. NATURE GENETICS
- Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4
- (2019) Fangjian Gao et al. MOLECULAR CELL
- Inhibition of MYC by the SMARCB1 tumor suppressor
- (2019) April M. Weissmiller et al. Nature Communications
- Epithelial keratins: Biology and implications as diagnostic markers for liquid biopsies
- (2019) Stefan Werner et al. MOLECULAR ASPECTS OF MEDICINE
- Frequent loss of claudin-4 expression in dedifferentiated and undifferentiated endometrial carcinomas
- (2018) Basile Tessier-Cloutier et al. HISTOPATHOLOGY
- Functions of EpCAM in physiological processes and diseases (Review)
- (2018) Li Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Epithelial-mesenchymal transition (EMT) signature is inversely associated with T-cell infiltration in non-small cell lung cancer (NSCLC)
- (2018) Young Kwang Chae et al. Scientific Reports
- The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas
- (2018) Ines Garces de los Fayos Alonso et al. Cancers
- Histone deacetylase inhibitors synergizes with catalytic inhibitors of EZH2 to exhibit anti-tumor activity in small cell carcinoma of the ovary, hypercalcemic type
- (2018) Yemin Wang et al. MOLECULAR CANCER THERAPEUTICS
- The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop
- (2018) Sherif Abd El-Fattah Ibrahim et al. Oncotarget
- RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management
- (2018) Kevin A. Kovalchik et al. JOURNAL OF PROTEOME RESEARCH
- A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
- (2018) Brittany C. Michel et al. NATURE CELL BIOLOGY
- The chromatin accessibility landscape of primary human cancers
- (2018) M. Ryan Corces et al. SCIENCE
- Comprehensive genomic profiling reveals inactivating SMARCA4 mutations and low tumor mutational burden in small cell carcinoma of the ovary, hypercalcemic-type
- (2017) Douglas I. Lin et al. GYNECOLOGIC ONCOLOGY
- Clinical, morphological and immunohistochemical evidence that small-cell carcinoma of the ovary of hypercalcaemic type (SCCOHT) may be a primitive germ-cell neoplasm
- (2017) W Glenn McCluggage et al. HISTOPATHOLOGY
- The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type
- (2017) Yemin Wang et al. JOURNAL OF PATHOLOGY
- Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease
- (2017) Malik Quasir Mahmood et al. MEDICAL ONCOLOGY
- Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas
- (2017) Inga-Marie Schaefer et al. MODERN PATHOLOGY
- AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection
- (2017) Thomas Vierbuchen et al. MOLECULAR CELL
- The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
- (2017) Burak H. Alver et al. Nature Communications
- Open chromatin profiling identifies AP1 as a transcriptional regulator in oesophageal adenocarcinoma
- (2017) Edward Britton et al. PLoS Genetics
- Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers
- (2017) Timothy W R Kelso et al. eLife
- An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites
- (2017) Peter J Skene et al. eLife
- Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics
- (2016) Blaise A Clarke et al. HISTOPATHOLOGY
- ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice
- (2016) Radhika Mathur et al. NATURE GENETICS
- Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type
- (2015) Anthony N Karnezis et al. JOURNAL OF PATHOLOGY
- Using Peptide-Level Proteomics Data for Detecting Differentially Expressed Proteins
- (2015) Tomi Suomi et al. JOURNAL OF PROTEOME RESEARCH
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes
- (2015) Jesse R. Raab et al. PLoS Genetics
- BRG1/SMARCA4 Inactivation Promotes Non-Small Cell Lung Cancer Aggressiveness by Altering Chromatin Organization
- (2014) T. Orvis et al. CANCER RESEARCH
- SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development
- (2014) Darmood Wei et al. MOLECULAR CANCER RESEARCH
- Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4
- (2014) Pilar Ramos et al. NATURE GENETICS
- Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type
- (2014) Leora Witkowski et al. NATURE GENETICS
- Recurrent SMARCA4 mutations in small cell carcinoma of the ovary
- (2014) Petar Jelinic et al. NATURE GENETICS
- Molecular mechanisms of epithelial–mesenchymal transition
- (2014) Samy Lamouille et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- AP-1/c-Jun transcription factors: Regulation and function in malignant melanoma
- (2013) Melanie Kappelmann et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions
- (2013) N. C. Sheffield et al. GENOME RESEARCH
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions
- (2013) Stephanie A Morris et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ovarian small cell carcinoma of hypercalcemic type – evidence of germline origin and smarca4 gene inactivation. a pilot study
- (2013) Jolanta Kupryjańczyk et al. POLISH JOURNAL OF PATHOLOGY
- Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters
- (2013) M. Y. Tolstorukov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small cell carcinoma of the ovary of the hypercalcaemic type: an analysis of clinical and prognostic aspects of a rare disease on the basis of cases published in the literature
- (2011) Rebecca Estel et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1
- (2011) G. Hu et al. GENOME RESEARCH
- Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding
- (2011) Simon C. Biddie et al. MOLECULAR CELL
- A Dominant-Negative c-jun Mutant Inhibits Lung Carcinogenesis in Mice
- (2010) J. W. Tichelaar et al. Cancer Prevention Research
- Biomarkers for epithelial-mesenchymal transitions
- (2009) Michael Zeisberg et al. JOURNAL OF CLINICAL INVESTIGATION
- Useful Immunohistochemical Markers of Tumor Differentiation
- (2009) J.T. Painter et al. TOXICOLOGIC PATHOLOGY
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