Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

(2020) Jonathan D. Mosley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A brief history of human disease genetics

(2020) Melina Claussnitzer et al.   NATURE

Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups

(2020) Ozan Dikilitas et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults

(2019) Luanluan Sun et al.   NATURE MEDICINE

2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary

(2019) Donna K. Arnett et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of communicating phenotypic and genetic risk of coronary heart disease alongside web-based lifestyle advice: the INFORM Randomised Controlled Trial

(2019) Barbora Silarova et al.   HEART

Stroke genetics: discovery, biology, and clinical applications

(2019) Martin Dichgans et al.   LANCET NEUROLOGY

Analysis of polygenic risk score usage and performance in diverse human populations

(2019) L. Duncan et al.   Nature Communications

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

(2019) Florian Wünnemann et al.   Circulation-Genomic and Precision Medicine

Genomic medicine for undiagnosed diseases

(2019) Anastasia L Wise et al.   LANCET

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

(2019) Gad Abraham et al.   Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Cardiovascular disease: The rise of the genetic risk score

(2018) Joshua W. Knowles et al.   PLOS MEDICINE

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies

(2018) Lisa Pennells et al.   EUROPEAN HEART JOURNAL

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult

(2016) Todd J. Anderson et al.   CANADIAN JOURNAL OF CARDIOLOGY

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults

(2016) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interpretation of the evidence for the efficacy and safety of statin therapy

(2016) Rory Collins et al.   LANCET

Data Resource Profile: Clinical Practice Research Datalink (CPRD)

(2015) Emily Herrett et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Tests of calibration and goodness-of-fit in the survival setting

(2015) Olga V. Demler et al.   STATISTICS IN MEDICINE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Net Reclassification Improvement: Computation, Interpretation, and Controversies

(2014) Maarten J.G. Leening et al.   ANNALS OF INTERNAL MEDICINE

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Net Reclassification Indices for Evaluating Risk Prediction Instruments

(2013) Kathleen F. Kerr et al.   EPIDEMIOLOGY

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

(2009) The Emerging Risk Factors Collaboration*   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

General Cardiovascular Risk Profile for Use in Primary Care

(2008) Ralph B. D’Agostino et al.   CIRCULATION