The scRNA-seq Expression Profiling of the Receptor ACE2 and the Cellular Protease TMPRSS2 Reveals Human Organs Susceptible to SARS-CoV-2 Infection
出版年份 2021 全文链接
标题
The scRNA-seq Expression Profiling of the Receptor ACE2 and the Cellular Protease TMPRSS2 Reveals Human Organs Susceptible to SARS-CoV-2 Infection
作者
关键词
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出版物
International Journal of Environmental Research and Public Health
Volume 18, Issue 1, Pages 284
出版商
MDPI AG
发表日期
2021-01-04
DOI
10.3390/ijerph18010284
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells
- (2020) Zhiyuan Hu et al. CANCER CELL
- Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
- (2020) Yushun Wan et al. JOURNAL OF VIROLOGY
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Decoding the development of the human hippocampus
- (2020) Suijuan Zhong et al. NATURE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- (2020) Nature Microbiology
- Digestive Symptoms in COVID-19 Patients With Mild Disease Severity
- (2020) Chaoqun Han et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses
- (2020) Furong Qi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- ACE2 Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2 Infection
- (2020) Furong Liu et al. Clinical Gastroenterology and Hepatology
- COVID-19 and Smoking. Is Nicotine the Hidden Link?
- (2020) Patrizia Russo et al. EUROPEAN RESPIRATORY JOURNAL
- ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
- (2020) Janice M. Leung et al. EUROPEAN RESPIRATORY JOURNAL
- Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis
- (2020) Xiu-wu Pan et al. INTENSIVE CARE MEDICINE
- Smoking-Mediated Upregulation of the Androgen Pathway Leads to Increased SARS-CoV-2 Susceptibility
- (2020) Jaideep Chakladar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic
- (2020) Elissa Driggin et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Gastrointestinal and Liver Manifestations in Patients with COVID-19
- (2020) I-Cheng Lee et al. Journal of the Chinese Medical Association
- Kidney disease is associated with in-hospital death of patients with COVID-19
- (2020) Yichun Cheng et al. KIDNEY INTERNATIONAL
- Construction of a human cell landscape at single-cell level
- (2020) Xiaoping Han et al. NATURE
- Virological assessment of hospitalized patients with COVID-2019
- (2020) Roman Wölfel et al. NATURE
- COVID-19: faecal–oral transmission?
- (2020) Jordan Hindson Nature Reviews Gastroenterology & Hepatology
- Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
- (2020) Shutoku Matsuyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
- (2020) Xiuyuan Ou et al. Nature Communications
- TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?
- (2020) Konrad H. Stopsack et al. Cancer Discovery
- Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection
- (2020) Xin Zou et al. Frontiers of Medicine
- scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells
- (2020) Zhengpin Wang et al. Cells
- Liver injury in COVID-19: management and challenges
- (2020) Chao Zhang et al. Lancet Gastroenterology & Hepatology
- Single-cell RNA Expression Profiling of ACE2, The Receptor of SARS-CoV-2
- (2020) Yu Zhao et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies
- (2020) Georgia Ragia et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Case series of headache characteristics in COVID‐19; Headache can be an isolated symptom
- (2020) Tuğçe Toptan et al. HEADACHE
- Potential fecal transmission of SARS-CoV-2: Current evidence and implications for public health
- (2020) E. Susan Amirian INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms
- (2020) Manuela Pennisi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Postmortem Kidney Pathology Findings in Patients with COVID-19
- (2020) Dominick Santoriello et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
- (2020) Benjamin T Bradley et al. LANCET
- Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor
- (2020) Yanwei Li et al. PHARMACOLOGICAL RESEARCH
- Anti‐androgens may protect against severe COVID‐19 outcomes: results from a prospective cohort study of 77 hospitalized men
- (2020) A. Goren et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- SARS-CoV-2 renal tropism associates with acute kidney injury
- (2020) Fabian Braun et al. LANCET
- ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection
- (2020) Lingli Zhou et al. Ocular Surface
- SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19
- (2020) Aristides Tsatsakis et al. FOOD AND CHEMICAL TOXICOLOGY
- Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2
- (2020) Yuanyuan Qiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart
- (2019) Yueli Cui et al. Cell Reports
- Single-cell reconstruction of follicular remodeling in the human adult ovary
- (2019) X. Fan et al. Nature Communications
- Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures
- (2019) Sandra Ruiz García et al. DEVELOPMENT
- Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils
- (2019) Akira Takeda et al. IMMUNITY
- Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway
- (2018) Tsing-Lee Tang-Huau et al. Nature Communications
- Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
- (2018) Paul A Reyfman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The adult human testis transcriptional cell atlas
- (2018) Jingtao Guo et al. CELL RESEARCH
- Impact of sequencing depth and read length on single cell RNA sequencing data of T cells
- (2017) Simone Rizzetto et al. Scientific Reports
- Revealing the vectors of cellular identity with single-cell genomics
- (2016) Allon Wagner et al. NATURE BIOTECHNOLOGY
- Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
- (2016) Marco Onorati et al. Cell Reports
- The promise of single-cell sequencing
- (2013) James Eberwine et al. NATURE METHODS
- Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments
- (2012) Andrew McDavid et al. BIOINFORMATICS
- Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor
- (2009) K. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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