Mapping Phosphodiesterase 4D (PDE4D) in Macaque Dorsolateral Prefrontal Cortex: Postsynaptic Compartmentalization in Layer III Pyramidal Cell Circuits

The Astrocytic cAMP Pathway in Health and Disease

(2019) Zhiwen Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of neuronal microtubule dynamics by tau: Implications for tauopathies

(2019) Anuradha Venkatramani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Therapeutic targeting of 3′,5′-cyclic nucleotide phosphodiesterases: inhibition and beyond

(2019) George S. Baillie et al.   NATURE REVIEWS DRUG DISCOVERY

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

(2019) Pascale Barbier et al.   Frontiers in Aging Neuroscience

Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia

(2018) Dibyadeep Datta et al.   ACS Chemical Neuroscience

Comparative ultrastructural features of excitatory synapses in the visual and frontal cortices of the adult mouse and monkey

(2017) Alexander Hsu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Transcriptome alterations of prefrontal cortical parvalbumin neurons in schizophrenia

(2017) J F Enwright III et al.   MOLECULAR PSYCHIATRY

A multiregional proteomic survey of the postnatal human brain

(2017) Becky C. Carlyle et al.   NATURE NEUROSCIENCE

Contacts between the endoplasmic reticulum and other membranes in neurons

(2017) Yumei Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners

(2016) Kirsty F. Houslay et al.   BIOCHEMICAL JOURNAL

Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling

(2016) Fikru B. Bedada et al.   Scientific Reports

Diversity of Glutamatergic Synaptic Strength in Lateral Prefrontal versus Primary Visual Cortices in the Rhesus Monkey

(2015) M. Medalla et al.   JOURNAL OF NEUROSCIENCE

Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder

(2015) D Arion et al.   MOLECULAR PSYCHIATRY

Stress weakens prefrontal networks: molecular insults to higher cognition

(2015) Amy F T Arnsten   NATURE NEUROSCIENCE

Cell type– and brain region–resolved mouse brain proteome

(2015) Kirti Sharma et al.   NATURE NEUROSCIENCE

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Perineuronal nets and schizophrenia: The importance of neuronal coatings

(2014) Byron K.Y. Bitanihirwe et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex

(2014) Becky C. Carlyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different mutations inPDE4Dassociated with developmental disorders with mirror phenotypes

(2013) Anna Lindstrand et al.   JOURNAL OF MEDICAL GENETICS

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

ERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertion

(2013) R. S. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perineuronal nets protect fast-spiking interneurons against oxidative stress

(2013) J.-H. Cabungcal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exome Sequencing Identifies PDE4D Mutations in Acrodysostosis

(2012) Hane Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Constellation of HCN Channels and cAMP Regulating Proteins in Dendritic Spines of the Primate Prefrontal Cortex: Potential Substrate for Working Memory Deficits in Schizophrenia

(2012) Constantinos D. Paspalas et al.   CEREBRAL CORTEX

Influence of Highly Distinctive Structural Properties on the Excitability of Pyramidal Neurons in Monkey Visual and Prefrontal Cortices

(2012) J. M. Amatrudo et al.   JOURNAL OF NEUROSCIENCE

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

The ageing cortical synapse: hallmarks and implications for cognitive decline

(2012) John H. Morrison et al.   NATURE REVIEWS NEUROSCIENCE

Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses

(2012) Amy F.T. Arnsten et al.   NEURON

Phosphorylation of cAMP-specific PDE4A5 (phosphodiesterase-4A5) by MK2 (MAPKAPK2) attenuates its activation through protein kinase A phosphorylation

(2011) Kirsty F. MacKenzie et al.   BIOCHEMICAL JOURNAL

PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts

(2011) Brigitte E. Blackman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal basis of age-related working memory decline

(2011) Min Wang et al.   NATURE

A review of the structural alterations in the cerebral hemispheres of the aging rhesus monkey

(2011) Alan Peters et al.   NEUROBIOLOGY OF AGING

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

The Evolution of the Brain, the Human Nature of Cortical Circuits, and Intellectual Creativity

(2011) Javier DeFelipe   Frontiers in Neuroanatomy

Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase 4D

(2010) H. Zhu et al.   MOLECULAR AND CELLULAR BIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

(2009) T.W. Robbins et al.   Annual Review of Neuroscience

Association Between Genes of Disrupted in Schizophrenia 1 (DISC1) Interactors and Schizophrenia Supports the Role of the DISC1 Pathway in the Etiology of Major Mental Illnesses

(2009) Liisa Tomppo et al.   BIOLOGICAL PSYCHIATRY

Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases

(2009) George S. Baillie   FEBS Journal

PKA Has a Critical Role in Synaptic Delivery of GluR1- and GluR4-Containing AMPARs During Initial Stages of Acquisition of In Vitro Classical Conditioning

(2009) Zhaoqing Zheng et al.   JOURNAL OF NEUROPHYSIOLOGY