标题
Common germline-somatic variant interactions in advanced urothelial cancer
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-12-03
DOI
10.1038/s41467-020-19971-8
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Rucaparib for recurrent, locally advanced, or metastatic urothelial carcinoma (mUC): Results from ATLAS, a phase II open-label trial.
- (2020) Petros Grivas et al. JOURNAL OF CLINICAL ONCOLOGY
- Inherited causes of clonal haematopoiesis in 97,691 whole genomes
- (2020) Alexander G. Bick et al. NATURE
- Altered myogenesis and premature senescence underlie human TRIM32-related myopathy
- (2019) E. Servián-Morilla et al. Acta Neuropathologica Communications
- g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
- (2019) Uku Raudvere et al. NUCLEIC ACIDS RESEARCH
- Germline Variants Impact Somatic Events during Tumorigenesis
- (2019) Johnny R. Ramroop et al. TRENDS IN GENETICS
- Tumour lineage shapes BRCA-mediated phenotypes
- (2019) Philip Jonsson et al. NATURE
- Structural basis of TFIIH activation for nucleotide excision repair
- (2019) Goran Kokic et al. Nature Communications
- Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling
- (2019) Minglei Wang et al. CELL DEATH AND DIFFERENTIATION
- Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes
- (2019) Pamela Feliciano et al. npj Genomic Medicine
- 902OAn adaptive, biomarker directed platform study in metastatic urothelial cancer (BISCAY) with durvalumab in combination with targeted therapies
- (2019) T Powles et al. ANNALS OF ONCOLOGY
- LBA12_PRPROfound: Phase III study of olaparib versus enzalutamide or abiraterone for metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations
- (2019) M Hussain et al. ANNALS OF ONCOLOGY
- Prevalence of pathogenic germline cancer risk variants in high-risk urothelial carcinoma
- (2019) Amin H. Nassar et al. GENETICS IN MEDICINE
- Cancer Susceptibility Mutations in Patients With Urothelial Malignancies
- (2019) Maria I. Carlo et al. JOURNAL OF CLINICAL ONCOLOGY
- Germline mutations in DNA repair genes are associated with bladder cancer risk and unfavourable prognosis
- (2018) Rong Na et al. BJU INTERNATIONAL
- Pathogenic Germline Variants in 10,389 Adult Cancers
- (2018) Kuan-lin Huang et al. CELL
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
- (2018) Katherine A. Hoadley et al. CELL
- Somatic mutations precede acute myeloid leukemia years before diagnosis
- (2018) Pinkal Desai et al. NATURE MEDICINE
- Treatment resistance in urothelial carcinoma: an evolutionary perspective
- (2018) Panagiotis J. Vlachostergios et al. Nature Reviews Clinical Oncology
- Double agents: genes with both oncogenic and tumor-suppressor functions
- (2018) Libing Shen et al. Oncogenesis
- Accurate classification of BRCA1 variants with saturation genome editing
- (2018) Gregory M. Findlay et al. NATURE
- A universal SNP and small-indel variant caller using deep neural networks
- (2018) Ryan Poplin et al. NATURE BIOTECHNOLOGY
- CADD: predicting the deleteriousness of variants throughout the human genome
- (2018) Philipp Rentzsch et al. NUCLEIC ACIDS RESEARCH
- COSMIC: the Catalogue Of Somatic Mutations In Cancer
- (2018) John G Tate et al. NUCLEIC ACIDS RESEARCH
- Differences between germline and somatic mutation rates in humans and mice
- (2017) Brandon Milholland et al. Nature Communications
- Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations
- (2017) Franklin W. Huang et al. Cancer Discovery
- XPA: A key scaffold for human nucleotide excision repair
- (2016) Norie Sugitani et al. DNA REPAIR
- mutation3D: Cancer Gene Prediction Through Atomic Clustering of Coding Variants in the Structural Proteome
- (2016) Michael J. Meyer et al. HUMAN MUTATION
- Familial Risk and Heritability of Cancer Among Twins in Nordic Countries
- (2016) Lorelei A. Mucci et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Analysis of protein-coding genetic variation in 60,706 humans
- (2016) Monkol Lek et al. NATURE
- Clonal evolution of chemotherapy-resistant urothelial carcinoma
- (2016) Bishoy M Faltas et al. NATURE GENETICS
- Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors
- (2016) D. Williams Parsons et al. JAMA Oncology
- Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care
- (2016) Hanna Rennert et al. npj Genomic Medicine
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
- TP53: an oncogene in disguise
- (2015) T Soussi et al. CELL DEATH AND DIFFERENTIATION
- Oncotator: Cancer Variant Annotation Tool
- (2015) Alex H. Ramos et al. HUMAN MUTATION
- TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes
- (2015) Min Zhao et al. NUCLEIC ACIDS RESEARCH
- Comprehensive assessment of cancer missense mutation clustering in protein structures
- (2015) Atanas Kamburov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patterns and functional implications of rare germline variants across 12 cancer types
- (2015) Charles Lu et al. Nature Communications
- Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response
- (2015) Himisha Beltran et al. JAMA Oncology
- Clinical Evaluation of a Multiple-Gene Sequencing Panel for Hereditary Cancer Risk Assessment
- (2014) Allison W. Kurian et al. JOURNAL OF CLINICAL ONCOLOGY
- Realizing the promise of cancer predisposition genes
- (2014) Nazneen Rahman NATURE
- A general framework for estimating the relative pathogenicity of human genetic variants
- (2014) Martin Kircher et al. NATURE GENETICS
- Integrated analysis of germline and somatic variants in ovarian cancer
- (2014) Krishna L. Kanchi et al. Nature Communications
- Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins
- (2014) Shai Carmi et al. Nature Communications
- Organizing Principles of Mammalian Nonsense-Mediated mRNA Decay
- (2013) Maximilian Wei-Lin Popp et al. Annual Review of Genetics
- Integrated genomic characterization of endometrial carcinoma
- (2013) Gad Getz et al. NATURE
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
- Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
- (2012) Christopher T. Saunders et al. BIOINFORMATICS
- A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff
- (2012) Pablo Cingolani et al. FLY
- VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
- (2012) D. C. Koboldt et al. GENOME RESEARCH
- Shining a Light on Xeroderma Pigmentosum
- (2012) John J. DiGiovanna et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- SomaticSniper: identification of somatic point mutations in whole genome sequencing data
- (2011) David E. Larson et al. BIOINFORMATICS
- A framework for variation discovery and genotyping using next-generation DNA sequencing data
- (2011) Mark A DePristo et al. NATURE GENETICS
- Genetic Heterogeneity in Human Disease
- (2010) Jon McClellan et al. CELL
- The EPHB6 Receptor Tyrosine Kinase Is a Metastasis Suppressor That Is Frequently Silenced by Promoter DNA Hypermethylation in Non-Small Cell Lung Cancer
- (2010) J. Yu et al. CLINICAL CANCER RESEARCH
- Somatic mutations and germline sequence variants in patients with familial colorectal cancer
- (2010) Alexandra E. Gylfe et al. INTERNATIONAL JOURNAL OF CANCER
- XPA Gene Mutations Resulting in Subtle Truncation of Protein in Xeroderma Pigmentosum Group A Patients with Mild Skin Symptoms
- (2010) Yoshito Takahashi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A Tumor-Protective Role for Human Kallikrein-Related Peptidase 6 in Breast Cancer Mediated by Inhibition of Epithelial-to-Mesenchymal Transition
- (2009) G. Pampalakis et al. CANCER RESEARCH
- EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells
- (2009) B P Fox et al. ONCOGENE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now