AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis
出版年份 2020 全文链接
标题
AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-11-16
DOI
10.1038/s41467-020-19668-y
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
- (2018) Rohit Loomba et al. GASTROENTEROLOGY
- Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice
- (2018) Qian Zhao et al. MOLECULAR PHARMACEUTICS
- Liver inflammation and fibrosis
- (2017) Yukinori Koyama et al. JOURNAL OF CLINICAL INVESTIGATION
- A potent peptide as adiponectin receptor 1 agonist to against fibrosis
- (2017) Lingman Ma et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Structural insights into adiponectin receptors suggest ceramidase activity
- (2017) Ieva Vasiliauskaité-Brooks et al. NATURE
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Unraveling the Regulation of Hepatic Metabolism by Insulin
- (2017) Paul M. Titchenell et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The role of the extracellular matrix in primary myelofibrosis
- (2017) O Leiva et al. Blood Cancer Journal
- Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
- (2016) Matthew James Armstrong et al. LANCET
- Targeting hepatic glucose metabolism in the treatment of type 2 diabetes
- (2016) Amy K. Rines et al. NATURE REVIEWS DRUG DISCOVERY
- Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies
- (2016) Giovanni Musso et al. NATURE REVIEWS DRUG DISCOVERY
- Endoplasmic reticulum proteostasis in hepatic steatosis
- (2016) Andrei Baiceanu et al. Nature Reviews Endocrinology
- Developmental origins of NAFLD: a womb with a clue
- (2016) Stephanie R. Wesolowski et al. Nature Reviews Gastroenterology & Hepatology
- Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury
- (2016) Huafeng Wang et al. Scientific Reports
- Non-Alcoholic Steatohepatitis: Limited Available Treatment Options but Promising Drugs in Development and Recent Progress Towards a Regulatory Approval Pathway
- (2015) Claudia Filozof et al. DRUGS
- Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
- (2015) Michal Pawlak et al. JOURNAL OF HEPATOLOGY
- Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria
- (2015) Junqiu Xie et al. JOURNAL OF PEPTIDE SCIENCE
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Crystal structures of the human adiponectin receptors
- (2015) Hiroaki Tanabe et al. NATURE
- Adipocytokines and hepatic fibrosis
- (2015) Neeraj K. Saxena et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Is the adiponectin-AMPK-mitochondrial axis involved in progression of nonalcoholic fatty liver disease?
- (2014) Srinivasan Dasarathy HEPATOLOGY
- Role of Mitochondria in Nonalcoholic Fatty Liver Disease
- (2014) Fatiha Nassir et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Integrated physiology and systems biology of PPARα
- (2014) Sander Kersten Molecular Metabolism
- Comparative Effectiveness and Safety of Medications for Type 2 Diabetes: An Update Including New Drugs and 2-Drug Combinations
- (2013) Wendy L. Bennett et al. ANNALS OF INTERNAL MEDICINE
- Adiponectin Receptor as a Key Player in Healthy Longevity and Obesity-Related Diseases
- (2013) Toshimasa Yamauchi et al. Cell Metabolism
- Adiponectin receptor 1 enhances fatty acid metabolism and cell survival in palmitate-treated HepG2 cells through the PI3 K/AKT pathway
- (2013) I-Pin Chou et al. EUROPEAN JOURNAL OF NUTRITION
- Reduced adiponectin signaling due to weight gain results in nonalcoholic steatohepatitis through impaired mitochondrial biogenesis
- (2013) Priya Handa et al. HEPATOLOGY
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
- (2013) Miki Okada-Iwabu et al. NATURE
- Convergent pathways that cause hepatic fibrosis in NASH
- (2013) Scott L. Friedman Nature Reviews Gastroenterology & Hepatology
- PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
- (2012) T Verfaillie et al. CELL DEATH AND DIFFERENTIATION
- Crystal structure of a single-chain trimer of human adiponectin globular domain
- (2012) Xiaoshan Min et al. FEBS LETTERS
- A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis
- (2011) Vlad Ratziu et al. HEPATOLOGY
- Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
- (2010) Herbert Tilg et al. HEPATOLOGY
- Adiponectin-induced ERK and Akt Phosphorylation Protects against Pancreatic Beta Cell Apoptosis and Increases Insulin Gene Expression and Secretion
- (2010) Nadeeja Wijesekara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1
- (2010) Masato Iwabu et al. NATURE
- Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype
- (2009) Koji Ohashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice
- (2008) Kengo Tomita et al. HEPATOLOGY
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