Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-δ in sepsis-associated liver injury

Activated protein C inhibits LPS-mediated acetylation and secretion of HMGB1 in endothelial cells

(2019) Xiaofeng Cai et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Glycyrrhizin suppresses the expressions of HMGB1 and ameliorates inflammative effect after acute subarachnoid hemorrhage in rat model

(2018) Chengcheng Ieong et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Liver dysfunction in sepsis

(2018) Ewa Woźnica et al.   Advances in Clinical and Experimental Medicine

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

(2018) Meihong Deng et al.   IMMUNITY

HMGB1 is a promising therapeutic target for acute liver failure

(2017) Tetsu Yamamoto et al.   Expert Review of Gastroenterology & Hepatology

Sphingosine kinase 1 inhibition improves lipopolysaccharide/D-galactosamine-induced acute liver failure by inhibiting mitogen-activated protein kinases pathway

(2016) Tao Tian et al.   United European Gastroenterology Journal

Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1β, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death

(2015) Yusuke Toki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group box 1 cytoplasmic translocation in liver cells

(2015) Yan-Chang Lei   WORLD JOURNAL OF GASTROENTEROLOGY

Sphingosine kinase 1 dependent protein kinase C-δ activation plays an important role in acute liver failure in mice

(2015) Yan-Chang Lei   WORLD JOURNAL OF GASTROENTEROLOGY

PARP-1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation

(2014) Zhiyong Yang et al.   JOURNAL OF IMMUNOLOGY

JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

(2014) B. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC4: mechanism of regulation and biological functions

(2014) Zhengke Wang et al.   Epigenomics

The Role of Sphingosine Kinase 1 in Patients With Severe Acute Pancreatitis

(2012) Qiurong Li et al.   ANNALS OF SURGERY

Sphingosine Kinase 1 Is Required for Mesothelioma Cell Proliferation: Role of Histone Acetylation

(2012) Satish Kalari et al.   PLoS One

Dengue Virus Infection Mediates HMGB1 Release from Monocytes Involving PCAF Acetylase Complex and Induces Vascular Leakage in Endothelial Cells

(2012) Siew Pei Ong et al.   PLoS One

HMGB1 cytoplasmic translocation in patients with acute liver failure

(2011) Rong-Rong Zhou et al.   BMC GASTROENTEROLOGY

Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma

(2011) Meiyan Bao et al.   LIVER INTERNATIONAL

Gadolinium Chloride Augments Tumor-Specific Imaging of Targeted Quantum Dots In Vivo

(2010) Parmeswaran Diagaradjane et al.   ACS Nano

Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-β

(2010) Minggang Zhang et al.   HEPATOLOGY

High Mobility Group Box 1 Release from Hepatocytes during Ischemia and Reperfusion Injury Is Mediated by Decreased Histone Deacetylase Activity

(2010) John Evankovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective Effect of High-Mobility Group Box 1 Blockade on Acute Liver Failure in Rats

(2010) Kiminori Takano et al.   SHOCK

Synthesis and Evaluation of Sphingosine Analogues as Inhibitors of Sphingosine Kinases

(2009) Lingkai Wong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

(2009) D. Nayak et al.   NEUROSCIENCE

The   isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

(2009) J. Backs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

14-3-3 regulates the nuclear import of class IIa histone deacetylases

(2008) Tomonori G. Nishino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages

(2007) Samar M. Hammad et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS