Visible-light-mediated deuteration of aldehydes with D2O via polarity-matched reversible hydrogen atom transfer

Deuteration of Formyl Groups via a Catalytic Radical H/D Exchange Approach

(2020) Yueteng Zhang et al.   ACS Catalysis

Practical synthesis of C1 deuterated aldehydes enabled by NHC catalysis

(2019) Huihui Geng et al.   Nature Catalysis

Palladium/Rhodium Cooperative Catalysis for the Production of Aryl Aldehydes and Their Deuterated Analogues Using the Water-Gas Shift Reaction

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Selective α-Monomethylation by an Amine-Borane/N,N-Dimethylformamide System as the Methyl Source

(2018) Hui-Min Xia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Functionalisation for Hydrogen Isotope Exchange

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals

(2018) J. Luke Koniarczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

Controllable deuteration of halogenated compounds by photocatalytic D2O splitting

(2018) Cuibo Liu et al.   Nature Communications

General and Practical Potassium Methoxide/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides

(2018) Xin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deoxygenative Deuteration of Carboxylic Acids with D2 O

(2018) Muliang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Toolbox Approach To Construct Broadly Applicable Metal-Free Catalysts for Photoredox Chemistry: Deliberate Tuning of Redox Potentials and Importance of Halogens in Donor–Acceptor Cyanoarenes

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Selective sp3 C–H alkylation via polarity-match-based cross-coupling

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Catalytic Deuteration of Aldehydes with D2O

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Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis

(2016) Markus D. Kärkäs et al.   CHEMICAL REVIEWS

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

(2016) Tim Cernak et al.   CHEMICAL SOCIETY REVIEWS

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoretentive Deuteration of α-Chiral Amines with D2O

(2016) Lillian V. A. Hale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-catalysed tritiation of pharmaceuticals

(2016) Renyuan Pony Yu et al.   NATURE

Deuterated drugs draw heavier backing

(2016) Asher Mullard   NATURE REVIEWS DRUG DISCOVERY

Donor–Acceptor Fluorophores for Visible-Light-Promoted Organic Synthesis: Photoredox/Ni Dual Catalytic C(sp3)–C(sp2) Cross-Coupling

(2016) Jian Luo et al.   ACS Catalysis

Divergent CH Insertion-Cyclization Cascades ofN-Allyl Ynamides

(2015) Holly V. Adcock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isotope chemistry; a useful tool in the drug discovery arsenal

(2015) Charles S. Elmore et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Computational Tools To Model Halogen Bonds in Medicinal Chemistry

(2015) Melissa Coates Ford et al.   JOURNAL OF MEDICINAL CHEMISTRY

Experimental and Theoretical Mechanistic Investigation of the Iridium-Catalyzed Dehydrogenative Decarbonylation of Primary Alcohols

(2015) Esben P. K. Olsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiyl Radicals in Organic Synthesis

(2014) Fabrice Dénès et al.   CHEMICAL REVIEWS

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

(2013) Christopher K. Prier et al.   CHEMICAL REVIEWS

Using Deuterium in Drug Discovery: Leaving the Label in the Drug

(2013) Thomas G. Gant   JOURNAL OF MEDICINAL CHEMISTRY

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

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Isotopic labelling studies for a gold-catalysed skeletal rearrangement of alkynyl aziridines

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Hydrogen-Deuterium Exchange Reactions of Aromatic Compounds and Heterocycles by NaBD4-Activated Rhodium, Platinum and Palladium Catalysts

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