Arsenic-induced HER2 promotes proliferation, migration and angiogenesis of bladder epithelial cells via activation of multiple signaling pathways in vitro and in vivo

Health effects inflicted by chronic low‐level arsenic contamination in groundwater: A global public health challenge

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Enrichment of genes associated with squamous differentiation in cancer initiating cells isolated from urothelial cells transformed by the environmental toxicant arsenite

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Association and risk of five miRNAs with arsenic-induced multiorgan damage

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Trends and Challenges in Tumor Anti-Angiogenic Therapies

(2019) József Jászai et al.   Cells

Chronic exposure to submicromolar arsenite promotes the migration of human esophageal Het1A cells induced by heparin-binding EGF-like growth factor

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Akt Regulated Phosphorylation of GSK-3β/Cyclin D1, p21 and p27 Contributes to Cell Proliferation Through Cell Cycle Progression From G1 to S/G2M Phase in Low-Dose Arsenite Exposed HaCat Cells

(2019) Yao Chen et al.   Frontiers in Pharmacology

Estimating the risk of bladder and kidney cancer from exposure to low-levels of arsenic in drinking water, Nova Scotia, Canada

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Mechanisms of receptor tyrosine kinase activation in cancer

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Nuclear factor 90 promotes angiogenesis by regulating HIF-1α/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer

(2018) Wenqian Zhang et al.   Cell Death & Disease

HER2/EGFR-AKT signaling switches TGF-β from inhibiting cell proliferation to promoting cell migration in breast cancer

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HER2 and Src co-regulate proliferation, migration and transformation by downstream signaling pathways in arsenite-treated human uroepithelial cells

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Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

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Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer

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Cyclooxygenase-2 in cancer: A review

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B7-H3 promotes multiple myeloma cell survival and proliferation by ROS-dependent activation of Src/STAT3 and c-Cbl-mediated degradation of SOCS3

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Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo

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Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic

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Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic

(2016) Dalsu Baris et al.   JNCI-Journal of the National Cancer Institute

Compromised MAPK signaling in human diseases: an update

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Inhibition of the autocrine IL-6–JAK2–STAT3–calprotectin axis as targeted therapy for HR−/HER2+breast cancers

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DMAVin Drinking Water Activated NF-κB Signal Pathway and Increased TGF-βand IL-1βExpressions in Bladder Epithelial Cells of Rats

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Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells

(2015) Rachel J. Person et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics

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Dimethylarsinic acid (DMAV) changed the expressions of proliferative related factors and secretion of inflammatory cytokines in rat bladder

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Targeting JAK1/STAT3 Signaling Suppresses Tumor Progression and Metastasis in a Peritoneal Model of Human Ovarian Cancer

(2014) W. Wen et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Oxidative stress and MAPK involved into ATF2 expression in immortalized human urothelial cells treated by arsenic

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The ErbB/HER family of protein-tyrosine kinases and cancer

(2013) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Angiogenesis, mediated by miR-21, is involved arsenite-induced carcinogenesis

(2013) Yue Zhao et al.   TOXICOLOGY LETTERS

Hallmarks of Cancer: The Next Generation

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Akt Activation Is Responsible for Enhanced Migratory and Invasive Behavior of Arsenic-Transformed Human Bronchial Epithelial Cells

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p38 Mitogen-Activated Protein Kinase-Driven MAPKAPK2 Regulates Invasion of Bladder Cancer by Modulation of MMP-2 and MMP-9 Activity

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Lapatinib: A dual inhibitor of human epidermal growth factor receptor tyrosine kinases

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