HER2 and Src co-regulate proliferation, migration and transformation by downstream signaling pathways in arsenite-treated human uroepithelial cells

Estimating the risk of bladder and kidney cancer from exposure to low-levels of arsenic in drinking water, Nova Scotia, Canada

(2018) Nathalie Saint-Jacques et al.   ENVIRONMENT INTERNATIONAL

DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells

(2018) Toshihiro Tajirika et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

N 6 -methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells

(2018) Shiyan Gu et al.   TOXICOLOGY LETTERS

Prognostic Value of Molecular Breast Cancer Subtypes based on Her2, ESR1, PGR and Ki67 mRNA-Expression in Muscle Invasive Bladder Cancer

(2018) M.C. Kriegmair et al.   Translational Oncology

Epidermal Growth Factor Receptor Family Inhibition Identifies P38 Mitogen-activated Protein Kinase as a Potential Therapeutic Target in Bladder Cancer

(2018) Regina Mora Vidal et al.   UROLOGY

Cyclooxygenase inhibitors potentiate receptor tyrosine kinase therapies in bladder cancer cells in vitro

(2018) Jennifer Bourn et al.   Drug Design Development and Therapy

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence

(2017) Chin-Chi Kuo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low concentration arsenite activated JAK2/STAT3 signal and increased proliferative factor expressions in SV-HUC-1cells after short and long time treatment

(2017) Li Mengdan et al.   ENVIRONMENTAL TOXICOLOGY

The expression of keratin 6 is regulated by the activation of the ERK1/2 pathway in arsenite transformed human urothelial cells

(2017) Andrea Slusser-Nore et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells

(2017) Chengzhi Chen et al.   TOXICOLOGY LETTERS

High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression

(2015) Elpetra P. M. Timmermans-Sprang et al.   BMC CANCER

Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of Antioxidants

(2015) Arif Jan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Sodium Arsenite on Mouse Skin Carcinogenesis

(2015) Mónica A. Palmieri et al.   TOXICOLOGIC PATHOLOGY

Interaction of CDCP1 with HER2 Enhances HER2-Driven Tumorigenesis and Promotes Trastuzumab Resistance in Breast Cancer

(2015) Abdullah Alajati et al.   Cell Reports

HIF-1α pathway: role, regulation and intervention for cancer therapy

(2015) Georgina N. Masoud et al.   Acta Pharmaceutica Sinica B

Src Drives Growth of Antiestrogen Resistant Breast Cancer Cell Lines and Is a Marker for Reduced Benefit of Tamoxifen Treatment

(2015) Sarah L. Larsen et al.   PLoS One

VEGF and Colon Cancer Growth Beyond Angiogenesis: Does VEGF Directly Mediate Colon Cancer Growth Via a Non-angiogenic Mechanism?

(2014) Amrita Ahluwalia et al.   CURRENT PHARMACEUTICAL DESIGN

Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence

(2014) Nathalie Saint-Jacques et al.   Environmental Health

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Arsenic induces the expressions of angiogenesis-related factors through PI3K and MAPK pathways in SV-HUC-1 human uroepithelial cells

(2013) Fei Wang et al.   TOXICOLOGY LETTERS

Prevalence, Clinicopathologic Associations, and Molecular Spectrum of ERBB2 (HER2) Tyrosine Kinase Mutations in Lung Adenocarcinomas

(2012) M. E. Arcila et al.   CLINICAL CANCER RESEARCH

Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes

(2012) Yuan Li et al.   TOXICOLOGY

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Assessing HER2 gene amplification as a potential target for therapy in invasive urothelial bladder cancer with a standardized methodology: results in 1005 patients

(2009) M. Lae et al.   ANNALS OF ONCOLOGY

Metabolism of arsenic in human liver: the role of membrane transporters

(2009) Zuzana Drobná et al.   ARCHIVES OF TOXICOLOGY

Understanding the Mechanisms Behind Trastuzumab Therapy for Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

(2009) Neil L. Spector et al.   JOURNAL OF CLINICAL ONCOLOGY

HER2Overexpression and Amplification in Urothelial Carcinoma of the Bladder Is Associated WithMYCCoamplification in a Subset of Cases

(2008) Donna E. Hansel et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

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(2008) Gengyun Wen et al.   MOLECULAR MEDICINE

Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis

(2007) Shengwen Shen et al.   MOLECULAR CARCINOGENESIS