N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

(2020) Linlin Zhang et al.   SCIENCE

N-Terminomics TAILS Identifies Host Cell Substrates of Poliovirus and Coxsackievirus B3 3C Proteinases That Modulate Virus Infection

(2018) Julienne M. Jagdeo et al.   JOURNAL OF VIROLOGY

RNA-virus proteases counteracting host innate immunity

(2017) Jian Lei et al.   FEBS LETTERS

Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2

(2017) Xinyu Zhu et al.   JOURNAL OF VIROLOGY

Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO

(2017) Xinyu Zhu et al.   VIROLOGY

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells

(2017) Michael Poppe et al.   PLoS Pathogens

Hydrophobic Tagging-Assisted N-Termini Enrichment for In-Depth N-Terminome Analysis

(2016) Lingfan Chen et al.   ANALYTICAL CHEMISTRY

The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

(2016) Marie Pourcelot et al.   BMC BIOLOGY

Ubiquitin signaling in immune responses

(2016) Hongbo Hu et al.   CELL RESEARCH

Improvement of Quantitative Measurements in Multiplex Proteomics Using High-Field Asymmetric Waveform Spectrometry

(2016) Sibylle Pfammatter et al.   JOURNAL OF PROTEOME RESEARCH

SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity

(2016) Tomonari Muramatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design

(2016) Fenghua Wang et al.   Scientific Reports

From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design

(2014) Rolf Hilgenfeld   FEBS Journal

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

Subsite cooperativity in protease specificity

(2009) Natasha M. Ng et al.   BIOLOGICAL CHEMISTRY

Primary human coculture model of alveolo-capillary unit to study mechanisms of injury to peripheral lung

(2009) Maria Iris Hermanns et al.   CELL AND TISSUE RESEARCH