标题
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 48, Pages 30566-30576
出版商
Proceedings of the National Academy of Sciences
发表日期
2020-11-18
DOI
10.1073/pnas.2009506117
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma
- (2020) Beatriz Salvador-Barbero et al. CANCER CELL
- Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer
- (2020) Anand Vasudevan et al. DEVELOPMENTAL CELL
- Acquisition of chromosome instability is a mechanism to evade oncogene addiction
- (2020) Lorena Salgueiro et al. EMBO Molecular Medicine
- p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer
- (2019) Xiao Fang et al. EXPERIMENTAL CELL RESEARCH
- Next-generation characterization of the Cancer Cell Line Encyclopedia
- (2019) Mahmoud Ghandi et al. NATURE
- Aneuploidy drives lethal progression in prostate cancer
- (2019) Konrad H. Stopsack et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Context is everything: aneuploidy in cancer
- (2019) Uri Ben-David et al. NATURE REVIEWS GENETICS
- Genomic and Functional Approaches to Understanding Cancer Aneuploidy
- (2018) Alison M. Taylor et al. CANCER CELL
- Genetic and transcriptional evolution alters cancer cell line drug response
- (2018) Uri Ben-David et al. NATURE
- Systematic identification of mutations and copy number alterations associated with cancer patient prognosis
- (2018) Joan C Smith et al. eLife
- Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
- (2017) Sydney M. Shaffer et al. NATURE
- A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
- (2017) Peter M Bruno et al. NATURE MEDICINE
- iBH3: simple, fixable BH3 profiling to determine apoptotic priming in primary tissue by flow cytometry
- (2016) Jeremy Ryan et al. BIOLOGICAL CHEMISTRY
- The presence of extra chromosomes leads to genomic instability
- (2016) Verena Passerini et al. Nature Communications
- No current evidence for widespread dosage compensation in S. cerevisiae
- (2016) Eduardo M Torres et al. eLife
- Selective advantage of trisomic human cells cultured in non-standard conditions
- (2016) Samuel D. Rutledge et al. Scientific Reports
- Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial
- (2015) M. Jamal-Hanjani et al. ANNALS OF ONCOLOGY
- Aneuploidy-induced cellular stresses limit autophagic degradation
- (2015) Stefano Santaguida et al. GENES & DEVELOPMENT
- Pan-cancer analysis of the extent and consequences of intratumor heterogeneity
- (2015) Noemi Andor et al. NATURE MEDICINE
- Short- and long-term effects of chromosome mis-segregation and aneuploidy
- (2015) Stefano Santaguida et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity
- (2015) Prabhat K. Singhal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset
- (2015) B. Seashore-Ludlow et al. Cancer Discovery
- Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes
- (2014) M. D. Hall et al. CANCER RESEARCH
- Aneuploidy: implications for protein homeostasis and disease
- (2014) A. B. Oromendia et al. Disease Models & Mechanisms
- HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells
- (2014) N. Donnelly et al. EMBO JOURNAL
- Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin
- (2014) Nasma D. Eljack et al. Metallomics
- Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles
- (2014) L. M. Zasadil et al. Science Translational Medicine
- Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast
- (2014) Noah Dephoure et al. eLife
- A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
- (2013) J. M. Sheltzer CANCER RESEARCH
- Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome
- (2013) Teresa Davoli et al. CELL
- Aneuploid yeast strains exhibit defects in cell growth and passage through START
- (2013) Rebecca R. Thorburn et al. MOLECULAR BIOLOGY OF THE CELL
- CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy
- (2012) A. Kathleen McClendon et al. CELL CYCLE
- p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3
- (2012) William H. Chappell et al. CELL CYCLE
- Cancer cells preferentially lose small chromosomes
- (2012) Pascal H.G. Duijf et al. INTERNATIONAL JOURNAL OF CANCER
- Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition
- (2012) Jeffry L. Dean et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
- (2012) Silvia Stingele et al. Molecular Systems Biology
- Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
- (2012) Wanjuan Yang et al. NUCLEIC ACIDS RESEARCH
- Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile
- (2012) Ga Young Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Karyotypic Determinants of Chromosome Instability in Aneuploid Budding Yeast
- (2012) Jin Zhu et al. PLoS Genetics
- Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
- (2011) N. J. Birkbak et al. CANCER RESEARCH
- Chromosomal Instability Confers Intrinsic Multidrug Resistance
- (2011) A. J. X. Lee et al. CANCER RESEARCH
- Aneuploidy Drives Genomic Instability in Yeast
- (2011) J. M. Sheltzer et al. SCIENCE
- Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells☆
- (2010) Sanjeevani Arora et al. DNA REPAIR
- Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
- (2008) B. R. Williams et al. SCIENCE
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