Mechanisms and functions of calcium microdomains produced by ORAI channels, d-myo-inositol 1,4,5-trisphosphate receptors, or ryanodine receptors

IP3 mediated global Ca2+ signals arise through two temporally and spatially distinct modes of Ca2+ release

(2020) Jeffrey T Lock et al.   eLife

NAADP ‐regulated two‐pore channels drive phagocytosis through endo‐lysosomal Ca 2+ nanodomains, calcineurin and dynamin

(2020) Lianne C Davis et al.   EMBO JOURNAL

Microglial calcium signaling is attuned to neuronal activity in awake mice

(2020) Anthony D Umpierre et al.   eLife

Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons

(2020) Julia Hermann et al.   Frontiers in Cell and Developmental Biology

Store-operated calcium entry in disease: Beyond STIM/Orai expression levels

(2019) Sven Kappel et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structure and Function of IP3 Receptors

(2019) David L. Prole et al.   Cold Spring Harbor Perspectives in Biology

Imaging elemental events of store-operated Ca2+ entry in invading cancer cells with plasmalemmal targeted sensors

(2019) Fujian Lu et al.   JOURNAL OF CELL SCIENCE

Signaling through Ca2+ Microdomains from Store-Operated CRAC Channels

(2019) Pradeep Barak et al.   Cold Spring Harbor Perspectives in Biology

Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion

(2019) Xianan Qin et al.   BIOPHYSICAL JOURNAL

The Ca2+ export pump PMCA clears near-membrane Ca2+ to facilitate store-operated Ca2+ entry and NFAT activation

(2019) Christina K. Go et al.   Science Signaling

Modulation of Orai1 by cationic peptides triggers their direct cytosolic uptake

(2019) Cristiane R. Zuconelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Noise analysis of cytosolic calcium image data

(2019) Divya Swaminathan et al.   CELL CALCIUM

Three-dimensional spatio-temporal modelling of store operated Ca 2+ entry: Insights into ER refilling and the spatial signature of Ca 2+ signals

(2018) Emma McIvor et al.   CELL CALCIUM

STIM1 activation of adenylyl cyclase 6 connects Ca 2+ and cAMP signaling during melanogenesis

(2018) Rajender K Motiani et al.   EMBO JOURNAL

Spatially restricted subcellular Ca2+ signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism

(2018) Raphael Courjaret et al.   Scientific Reports

Applications of FLIKA, a Python-based image processing and analysis platform, for studying local events of cellular calcium signaling

(2018) Kyle L. Ellefsen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation

(2018) Björn-Philipp Diercks et al.   Science Signaling

IP3 Receptors Preferentially Associate with ER-Lysosome Contact Sites and Selectively Deliver Ca2+ to Lysosomes

(2018) Peace Atakpa et al.   Cell Reports

Ca2+ tunnelling through the ER lumen as a mechanism for delivering Ca2+ entering via store-operated Ca2+ channels to specific target sites

(2017) Ole H Petersen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ca 2+ microdomains, NAADP and type 1 ryanodine receptor in cell activation

(2016) Andreas H. Guse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Ca2+-activated Cl−channel Ano1 controls microvilli length and membrane surface area in the oocyte

(2016) Raphael Courjaret et al.   JOURNAL OF CELL SCIENCE

Store-Operated Ca2+Entry in Oocytes Modulate the Dynamics of IP3-Dependent Ca2+Release From Oscillatory to Tonic

(2016) Raphaël Courjaret et al.   JOURNAL OF CELLULAR PHYSIOLOGY

New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo

(2016) Rahul Srinivasan et al.   NEURON

Calcium signaling at ER membrane contact sites

(2015) Thomas Burgoyne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Both RyRs and TPCs are required for NAADP-induced intracellular Ca2+ release

(2015) Julia V. Gerasimenko et al.   CELL CALCIUM

The STIM1–ORAI1 microdomain

(2015) Patrick G Hogan   CELL CALCIUM

Distinct Structural Domains of Caveolin-1 Independently Regulate Ca2+Release-Activated Ca2+Channels and Ca2+Microdomain-Dependent Gene Expression

(2015) Yi-Chun Yeh et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetically targeted single-channel optical recording reveals multiple Orai1 gating states and oscillations in calcium influx

(2015) Joseph L. Dynes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frontrunners of T cell activation: Initial, localized Ca2+signals mediated by NAADP and the type 1 ryanodine receptor

(2015) Insa M. A. Wolf et al.   Science Signaling

Ca2+ Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca2+-Dependent Nuclear Gene Expression

(2015) Krishna Samanta et al.   Cell Reports

Frontrunners of T cell activation: Initial, localized Ca2+signals mediated by NAADP and the type 1 ryanodine receptor

(2015) Insa M. A. Wolf et al.   Science Signaling

Dynamic Assembly of a Membrane Signaling Complex Enables Selective Activation of NFAT by Orai1

(2014) Pulak Kar et al.   CURRENT BIOLOGY

Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum–plasma membrane junctions

(2014) Minnie M. Wu et al.   MOLECULAR BIOLOGY OF THE CELL

Mid-range Ca2+ signalling mediated by functional coupling between store-operated Ca2+ entry and IP3-dependent Ca2+ release

(2014) Raphaël Courjaret et al.   Nature Communications

A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells

(2014) Pengxing Cao et al.   PLoS Computational Biology

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling and Arrhythmias in the Heart Evoked by β-Adrenergic Stimulation

(2013) Merle Nebel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Degradation by Alkaline Phosphatase

(2012) Frederike Schmid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

CD38: A NAADP degrading enzyme

(2011) Frederike Schmid et al.   FEBS LETTERS

Selective Activation of the Transcription Factor NFAT1 by Calcium Microdomains near Ca2+Release-activated Ca2+(CRAC) Channels

(2011) Pulak Kar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system

(2010) Chiara Cordiglieri et al.   BRAIN

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking

(2010) Margarida Ruas et al.   CURRENT BIOLOGY

Coupling of Ca2+Microdomains to Spatially and Temporally Distinct Cellular Responses by the Tyrosine Kinase Syk

(2009) Siaw-Wei Ng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

(2009) W. Dammermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NAADP: A Universal Ca2+ Trigger

(2008) A. H. Guse et al.   Science Signaling

Polarized Calcium Signaling in Exocrine Gland Cells

(2007) Ole H. Petersen et al.   Annual Review of Physiology