Inhibition of PTEN Ameliorates Secondary Hippocampal Injury and Cognitive Deficits after Intracerebral Hemorrhage: Involvement of AKT/FoxO3a/ATG-Mediated Autophagy

Secondary injury to distal regions after intracerebral hemorrhage influence neurological functional outcome

(2020) Kangping Song et al.   Aging-US

Stroke accelerates and uncouples intrinsic and synaptic excitability maturation of mouse hippocampal DCX+ adult-born granule cells

(2019) Mihai Ceanga et al.   JOURNAL OF NEUROSCIENCE

Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway

(2019) Abubakar Wani et al.   Autophagy

Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy

(2019) Shi-Jie Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting GPER1 to suppress autophagy as a male-specific therapeutic strategy for iron-induced striatal injury

(2019) Tzu-Yun Chen et al.   Scientific Reports

Chronic inflammation, cognitive impairment, and distal brain region alteration following intracerebral hemorrhage

(2019) Elaine Shi et al.   FASEB JOURNAL

Experimental cortical stroke induces aberrant increase of sharp-wave-associated ripples in the hippocampus and disrupts cortico-hippocampal communication

(2019) Ji-Wei He et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Valproic acid attenuates sepsis-induced myocardial dysfunction in rats by accelerating autophagy through the PTEN/AKT/mTOR pathway

(2019) Xiaohui Shi et al.   LIFE SCIENCES

Increased perihematomal neuron autophagy and plasma thrombin–antithrombin levels in patients with intracerebral hemorrhage

(2019) Chenghan Wu et al.   MEDICINE

PTEN Inhibition Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury Through PTEN/E2F1/β-Catenin Pathway

(2019) Dan Zhao et al.   Frontiers in Molecular Neuroscience

FOXO3 links autophagy to apoptosis

(2018) Brent E. Fitzwalter et al.   Autophagy

Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage

(2018) Dan Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Changes in motor function, cognition, and emotion-related behavior after right hemispheric intracerebral hemorrhage in various brain regions of mouse

(2018) Wei Zhu et al.   BRAIN BEHAVIOR AND IMMUNITY

CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy

(2018) Junchao Cai et al.   NATURE CELL BIOLOGY

The functions and regulation of the PTEN tumour suppressor: new modes and prospects

(2018) Yu-Ru Lee et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Axonal autophagy: Mini-review for autophagy in the CNS

(2018) Andrea K.H. Stavoe et al.   NEUROSCIENCE LETTERS

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

(2018) Haiying Li et al.   PROGRESS IN NEUROBIOLOGY

Ultrastructural Characteristics of Neuronal Death and White Matter Injury in Mouse Brain Tissues After Intracerebral Hemorrhage: Coexistence of Ferroptosis, Autophagy, and Necrosis

(2018) Qian Li et al.   Frontiers in Neurology

Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy

(2018) Jin-Hwan Kim et al.   CELL DEATH AND DIFFERENTIATION

The social hippocampus

(2017) Alison Montagrin et al.   HIPPOCAMPUS

Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory phenotype

(2017) Jie Wu et al.   Journal of Neuroinflammation

Deciphering the promiscuous interactions between intrinsically disordered transactivation domains and the KIX domain

(2017) Yongqi Huang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

PTEN: Local and Global Modulation of Neuronal Function in Health and Disease

(2017) Shira Knafo et al.   TRENDS IN NEUROSCIENCES

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

(2016) Shira Knafo et al.   NATURE NEUROSCIENCE

ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells

(2015) Jing-Hong Chen et al.   Autophagy

Transcriptional and epigenetic regulation of autophagy in aging

(2015) Louis R Lapierre et al.   Autophagy

Impaired adult hippocampal neurogenesis and cognitive ability in a mouse model of intrastriatal hemorrhage

(2015) Yuan Yang et al.   NEUROSCIENCE LETTERS

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

(2014) You-Tong Wu et al.   Autophagy

The role of the hippocampus in flexible cognition and social behavior

(2014) Rachael D. Rubin et al.   Frontiers in Human Neuroscience

Functioning of long-term survivors of first-ever intracerebral hemorrhage

(2013) A. Tveiten et al.   ACTA NEUROLOGICA SCANDINAVICA

FOXO3A directs a protective autophagy program in haematopoietic stem cells

(2013) Matthew R. Warr et al.   NATURE

Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage

(2012) Chiu-Wei Chen et al.   Autophagy

Cognitive Impairment and Dementia After Intracerebral Hemorrhage: A Cross-sectional Study of a Hospital-based Series

(2012) Pierre Yves Garcia et al.   Journal of Stroke & Cerebrovascular Diseases

Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis

(2010) Charlotte JJ van Asch et al.   LANCET NEUROLOGY