NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway

Fasting‐ and ghrelin‐induced food intake is regulated by NAMPT in the hypothalamus

(2020) Roldan M. Guia et al.   Acta Physiologica

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway

(2020) Igor Shats et al.   Cell Metabolism

Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage

(2019) Alanna M. Cameron et al.   NATURE IMMUNOLOGY

Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice

(2019) Yuan-yuan Kong et al.   ACTA PHARMACOLOGICA SINICA

Both gain and loss of Nampt function promote pressure-overload-induced heart failure

(2019) Jaemin Byun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

(2019) Fabiola Marín‐Aguilar et al.   AGING CELL

Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2)

(2019) Marin Kuntic et al.   EUROPEAN HEART JOURNAL

Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT–NAD+–SIRT1 pathway

(2019) Rui Ma et al.   NUCLEIC ACIDS RESEARCH

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

Telomere length and reactive oxygen species levels are positively associated with a high risk of mortality and recurrence in hepatocellular carcinoma

(2018) Eunkyong Ko et al.   HEPATOLOGY

Activation of TP receptors induces high release of PGI2 in coronary arteries of renal hypertensive rats

(2018) T.D. Paula et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

De novo NAD+ synthesis enhances mitochondrial function and improves health

(2018) Elena Katsyuba et al.   NATURE

Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity

(2017) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015

(2017) Mohammad H. Forouzanfar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ursodeoxycholic Acid Attenuates Acute Aortic Dissection Formation in Angiotensin II-Infused Apolipoprotein E-Deficient Mice Associated with Reduced ROS and Increased Nrf2 Levels

(2016) Wanjun Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Physiological and pathophysiological roles of NAMPT and NAD metabolism

(2015) Antje Garten et al.   Nature Reviews Endocrinology

NAMPT suppresses glucose deprivation-induced oxidative stress by increasing NADPH levels in breast cancer

(2015) S M Hong et al.   ONCOGENE

Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors

(2014) Pei Wang et al.   CARDIOVASCULAR RESEARCH

Mechanism of Inhibition of the Human Sirtuin Enzyme SIRT3 by Nicotinamide: Computational and Experimental Studies

(2014) Xiangying Guan et al.   PLoS One

NAD+ and sirtuins in aging and disease

(2014) Shin-ichiro Imai et al.   TRENDS IN CELL BIOLOGY

A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury

(2013) Rachel K. Stewart et al.   JOURNAL OF HEPATOLOGY

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes

(2013) Soo Jin Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology

(2012) Tuva B. Dahl et al.   Annual Review of Nutrition

Nicotinamide Phosphoribosyl Transferase (Nampt) Is Required for De Novo Lipogenesis in Tumor Cells

(2012) Sarah C. Bowlby et al.   PLoS One

SIRT1 links CIITA deacetylation to MHC II activation

(2011) Xiaoyan Wu et al.   NUCLEIC ACIDS RESEARCH

Vaspin and visfatin/Nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus

(2010) Hala O. El-Mesallamy et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

(2009) Frédéric Van Gool et al.   NATURE MEDICINE

Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR

(2008) Fatiha Tabet et al.   CIRCULATION RESEARCH