Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-leukemia activities of selenium nanoparticles embedded in nanotube consisted of triple-helix β-d-glucan

(2020) Yanxia Jin et al.   CARBOHYDRATE POLYMERS

The novel thioredoxin reductase inhibitor A-Z2 triggers intrinsic apoptosis and shows efficacy in the treatment of acute myeloid leukemia

(2019) Dongdong Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway

(2019) Zhang Dongdong et al.   Frontiers in Pharmacology

Ubiquitin-dependent degradation of CDK2 drives the therapeutic differentiation of AML by targeting PRDX2

(2018) Meidan Ying et al.   BLOOD

Novel approaches to acute myeloid leukemia immunotherapy

(2018) Ofrat Beyar-Katz et al.   CLINICAL CANCER RESEARCH

Expression of reactive species related genes is associated with patient survival in luminal B breast cancer

(2018) Soumya Luthra et al.   FREE RADICAL BIOLOGY AND MEDICINE

Real-time detection and monitoring of the drug resistance of single myeloid leukemia cells by diffused total internal reflection

(2018) L. Liang et al.   LAB ON A CHIP

CAR T-cells targeting FLT3 have potent activity against FLT3−ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib

(2018) Hardikkumar Jetani et al.   LEUKEMIA

Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells

(2018) Rabindranath Bera et al.   NEOPLASIA

Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

(2018) Yanxia Jin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

FLT3 inhibitors in acute myeloid leukemia

(2018) Mei Wu et al.   Journal of Hematology & Oncology

Olfactory receptor 544 reduces adiposity by steering fuel preference toward fats

(2017) Chunyan Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Azelaic Acid Exerts Antileukemic Activity in Acute Myeloid Leukemia

(2017) Yunbao Pan et al.   Frontiers in Pharmacology

Optofluidic restricted imaging, spectroscopy and counting of nanoparticles by evanescent wave using immiscible liquids

(2016) L. Liang et al.   LAB ON A CHIP

Mitochondria in the Regulation of Innate and Adaptive Immunity

(2015) Samuel E. Weinberg et al.   IMMUNITY

Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells

(2014) S. Gill et al.   BLOOD

The ROS/SUMO Axis Contributes to the Response of Acute Myeloid Leukemia Cells to Chemotherapeutic Drugs

(2014) Guillaume Bossis et al.   Cell Reports

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling

(2013) P. S. Hole et al.   BLOOD

An Unexpected Link Between Notch Signaling and ROS in Restricting the Differentiation of Hematopoietic Progenitors in Drosophila

(2013) Chiyedza Small et al.   GENETICS

Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

(2013) Xinyuan Li et al.   Journal of Hematology & Oncology

Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia

(2013) Fuling Zhou et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells

(2012) Chuan-Xu Liu et al.   Nature Chemical Biology

Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy

(2011) Subash C. Gupta et al.   ANTIOXIDANTS & REDOX SIGNALING

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

(2011) S. Agrawal-Singh et al.   BLOOD

Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?

(2011) Federica Sotgia et al.   BMC Medicine

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Genetic instability in inherited and sporadic leukemias

(2010) Henning D. Popp et al.   GENES CHROMOSOMES & CANCER

Involvement of Oxidative Stress in the Relapse of Acute Myeloid Leukemia

(2010) Fu-Ling Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ras-induced reactive oxygen species promote growth factor-independent proliferation in human CD34+ hematopoietic progenitor cells

(2009) P. S. Hole et al.   BLOOD

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

Downregulation of thec-MYCtarget gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

(2009) Pablo E. Vivas-Mejía et al.   INTERNATIONAL JOURNAL OF CANCER

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

(2009) Paul J Boersema et al.   Nature Protocols

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML

(2008) A. Sallmyr et al.   BLOOD

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology