Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability
出版年份 2020 全文链接
标题
Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability
作者
关键词
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出版物
NUCLEIC ACIDS RESEARCH
Volume 49, Issue 2, Pages 954-968
出版商
Oxford University Press (OUP)
发表日期
2020-12-11
DOI
10.1093/nar/gkaa1241
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Consequences of epigenetic derepression in facioscapulohumeral muscular dystrophy
- (2020) Anna Greco et al. CLINICAL GENETICS
- Yeast Genome Maintenance by the Multifunctional PIF1 DNA Helicase Family
- (2020) Julius Muellner et al. Genes
- CRISPR/Cas Derivatives as Novel Gene Modulating Tools: Possibilities and In Vivo Applications
- (2020) Xingbo Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations
- (2019) Grégoire Cullot et al. Nature Communications
- Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
- (2019) Benjamin P. Kleinstiver et al. NATURE BIOTECHNOLOGY
- Transcription-mediated replication hindrance: a major driver of genome instability
- (2019) Belén Gómez-González et al. GENES & DEVELOPMENT
- DNA Copy Number Variations as Markers of Mutagenic Impact
- (2019) Galina Hovhannisyan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nuclease dead Cas9 is a programmable roadblock for DNA replication
- (2019) Kelsey S. Whinn et al. Scientific Reports
- NanoPack: visualizing and processing long-read sequencing data
- (2018) Wouter De Coster et al. BIOINFORMATICS
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation
- (2018) Emilie Ma et al. eLife
- Highly efficient genome editing by CRISPR-Cpf1 using CRISPR RNA with a uridinylate-rich 3′-overhang
- (2018) Su Bin Moon et al. Nature Communications
- R-loop formation by dCas9 is mutagenic in Saccharomyces cerevisiae
- (2018) Marian F Laughery et al. NUCLEIC ACIDS RESEARCH
- Properties of Mitotic and Meiotic Recombination in the Tandemly-RepeatedCUP1Gene Cluster in the YeastSaccharomyces cerevisiae
- (2017) Ying Zhao et al. GENETICS
- Ctf4 Prevents Genome Rearrangements by Suppressing DNA Double-Strand Break Formation and Its End Resection at Arrested Replication Forks
- (2017) Mariko Sasaki et al. MOLECULAR CELL
- Mechanism of tandem duplication formation in BRCA1-mutant cells
- (2017) Nicholas A. Willis et al. NATURE
- Environmental change drives accelerated adaptation through stimulated copy number variation
- (2017) Ryan M. Hull et al. PLOS BIOLOGY
- Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication
- (2017) Carl A Morrow et al. eLife
- Properties of Mitotic and Meiotic Recombination in the Tandemly-RepeatedCUP1Gene Cluster in the YeastSaccharomyces cerevisiae
- (2017) Ying Zhao et al. GENETICS
- More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance
- (2016) Kimiko Saka et al. NUCLEIC ACIDS RESEARCH
- Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells
- (2016) Sarah R Hengel et al. eLife
- Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers
- (2015) Gurushankar Chandramouly et al. CHEMISTRY & BIOLOGY
- The 100-genomes strains, anS. cerevisiaeresource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen
- (2015) Pooja K. Strope et al. GENOME RESEARCH
- Extrachromosomal circular DNA is common in yeast
- (2015) Henrik D. Møller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
- (2014) Yuki Naito et al. BIOINFORMATICS
- The Escherichia coli Tus–Ter replication fork barrier causes site-specific DNA replication perturbation in yeast
- (2014) Nicolai B. Larsen et al. Nature Communications
- Structures of Naturally Evolved CUP1 Tandem Arrays in Yeast Indicate That These Arrays Are Generated by Unequal Nonhomologous Recombination
- (2014) Ying Zhao et al. G3-Genes Genomes Genetics
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
- (2013) Baohui Chen et al. CELL
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Functional analyses of the C-terminal half of the Saccharomyces cerevisiae Rad52 protein
- (2013) W. Kagawa et al. NUCLEIC ACIDS RESEARCH
- Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
- (2013) James E. DiCarlo et al. NUCLEIC ACIDS RESEARCH
- Competition, collaboration and coordination - determining how cells bypass DNA damage
- (2012) J. E. Sale JOURNAL OF CELL SCIENCE
- Amplification of the CUP1 gene is associated with evolution of copper tolerance in Saccharomyces cerevisiae
- (2012) G. M. Adamo et al. MICROBIOLOGY-SGM
- Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast
- (2011) Takehiko Kobayashi CELLULAR AND MOLECULAR LIFE SCIENCES
- Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae
- (2011) R. Scott McIsaac et al. MOLECULAR BIOLOGY OF THE CELL
- Repetitive DNA and next-generation sequencing: computational challenges and solutions
- (2011) Todd J. Treangen et al. NATURE REVIEWS GENETICS
- Repeat expansion in the budding yeast ribosomal DNA can occur independently of the canonical homologous recombination machinery
- (2011) Jonathan Houseley et al. NUCLEIC ACIDS RESEARCH
- OriDB, the DNA replication origin database updated and extended
- (2011) C. C. Siow et al. NUCLEIC ACIDS RESEARCH
- An improved method for whole protein extraction from yeast Saccharomyces cerevisiae
- (2011) Tingting Zhang et al. YEAST
- Origin-Dependent Inverted-Repeat Amplification: A Replication-Based Model for Generating Palindromic Amplicons
- (2011) Bonita J. Brewer et al. PLoS Genetics
- Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification
- (2010) B. M. Green et al. SCIENCE
- Role of the Rad52 Amino-terminal DNA Binding Activity in DNA Strand Capture in Homologous Recombination
- (2009) Idina Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Histone Code for Chromatin Assembly
- (2008) Jeffrey Fillingham et al. CELL
- Interaction with RPA Is Necessary for Rad52 Repair Center Formation and for Its Mediator Activity
- (2008) Iben Plate et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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