Cellular and molecular pathobiology of heart failure with preserved ejection fraction
出版年份 2021 全文链接
标题
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
作者
关键词
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出版物
Nature Reviews Cardiology
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-01-11
DOI
10.1038/s41569-020-00480-6
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- IL‐11 in cardiac and renal fibrosis: Late to the party but a central player
- (2020) Benjamin Corden et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mechanistic Effects of Spironolactone on Cardiovascular and Renal Biomarkers in Heart Failure With Preserved Ejection Fraction
- (2020) Peder L. Myhre et al. Circulation-Heart Failure
- Identification of novel pheno-groups in heart failure with preserved ejection fraction using machine learning
- (2020) Åsa K Hedman et al. HEART
- Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity
- (2020) Ying H. Lin et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Unfolding Discoveries in Heart Failure
- (2020) Walter J. Paulus NEW ENGLAND JOURNAL OF MEDICINE
- HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
- (2020) Markus Wallner et al. Science Translational Medicine
- Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction
- (2020) Jordana B. Cohen et al. JACC-Heart Failure
- Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)
- (2020) James E. Udelson et al. AMERICAN HEART JOURNAL
- Research Priorities for Heart Failure With Preserved Ejection Fraction
- (2020) Sanjiv J. Shah et al. CIRCULATION
- Covariate adjusted reanalysis of the I-Preserve trial
- (2020) João Pedro Ferreira et al. Clinical Research in Cardiology
- Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future
- (2020) Jan Wintrich et al. Clinical Research in Cardiology
- Multiple Plasma Biomarkers for Risk Stratification in Patients With Heart Failure and Preserved Ejection Fraction
- (2020) Julio A. Chirinos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Treatment With Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
- (2020) Longfei Wang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Extended‐Release Oral Milrinone for the Treatment of Heart Failure With Preserved Ejection Fraction
- (2020) Shane Nanayakkara et al. Journal of the American Heart Association
- Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Prevalence of Cardiac Amyloidosis
- (2020) Virginia S. Hahn et al. JACC-Heart Failure
- Efficacy of Dapagliflozin on Renal Function and Outcomes in Patients with Heart Failure with Reduced Ejection Fraction: Results of DAPA-HF
- (2020) Pardeep S. Jhund et al. CIRCULATION
- Proteomic Evaluation of the Comorbidity-Inflammation Paradigm in Heart Failure with Preserved Ejection Fraction:Results from the PROMIS-HFpEF Study
- (2020) Sandra Sanders-van Wijk et al. CIRCULATION
- Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure
- (2020) Milton Packer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reduced Right Ventricular Sarcomere Contractility in HFpEF with Severe Obesity
- (2020) M. Imran Aslam et al. CIRCULATION
- Myocardial Gene Expression Signatures in Human Heart Failure With Preserved Ejection Fraction
- (2020) Virginia S. Hahn et al. CIRCULATION
- Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling
- (2019) Takeshi Suetomi et al. CIRCULATION
- The β-Adrenergic Agonist Albuterol Improves Pulmonary Vascular Reserve in Heart Failure With Preserved Ejection Fraction
- (2019) Yogesh N.V. Reddy et al. CIRCULATION RESEARCH
- Relationship Between Focal and Diffuse Fibrosis Assessed by CMR and Clinical Outcomes in Heart Failure With Preserved Ejection Fraction
- (2019) Prathap Kanagala et al. JACC-Cardiovascular Imaging
- PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
- (2019) Mark J. Ranek et al. NATURE
- Combining Circulating MicroRNA and NT-proBNP to Detect and Categorize Heart Failure Subtypes
- (2019) Lee Lee Wong et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Heart Failure With Preserved Ejection Fraction and Diabetes
- (2019) Kelly McHugh et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- CaMKII signaling in heart diseases: Emerging role in diabetic cardiomyopathy
- (2019) Bence Hegyi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Heart Failure With Preserved Ejection Fraction Infrequently Evolves Toward a Reduced Phenotype in Long-Term Survivors
- (2019) Josep Lupón et al. Circulation-Heart Failure
- Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency
- (2019) Kim L Ho et al. CARDIOVASCULAR RESEARCH
- The Impact of APOL1 on Chronic Kidney Disease and Hypertension
- (2019) Todd W. Robinson et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- Cardiorenal syndrome in heart failure with preserved ejection fraction—an under-recognized clinical entity
- (2019) Akanksha Agrawal et al. HEART FAILURE REVIEWS
- Exercise Intolerance in Patients With Heart Failure
- (2019) Marco Giuseppe Del Buono et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Nitrosative stress drives heart failure with preserved ejection fraction
- (2019) Gabriele G. Schiattarella et al. NATURE
- In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
- (2019) Brian Leei Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arterial Remodeling and Dysfunction in the ZSF1 Rat Model of Heart Failure With Preserved Ejection Fraction
- (2019) Sara Leite et al. Circulation-Heart Failure
- Rationale and design of the EMPERIAL-Preserved and EMPERIAL-Reduced trials of empagliflozin in patients with chronic heart failure
- (2019) William T. Abraham et al. EUROPEAN JOURNAL OF HEART FAILURE
- Pulmonary hypertension and right ventricular remodeling in HFpEF and HFrEF
- (2019) Stefano Ghio et al. HEART FAILURE REVIEWS
- Inflammation in non-ischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling
- (2019) Takeshi Suetomi et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis
- (2019) Yang Xiao et al. GENES & DEVELOPMENT
- CaMKII Activity in the Inflammatory Response of Cardiac Diseases
- (2019) Maria Rosaria Rusciano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hemodynamic, Hormonal, and Renal Actions of Phosphodiesterase-9 Inhibition in Experimental Heart Failure
- (2019) Nicola J.A. Scott et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction
- (2019) Scott D. Solomon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chronic Kidney Disease as a Risk Factor for Heart Failure With Preserved Ejection Fraction: A Focus on Microcirculatory Factors and Therapeutic Targets
- (2019) Jens van de Wouw et al. Frontiers in Physiology
- Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction
- (2019) Dan Tong et al. CIRCULATION
- Myocardial Energetics in Heart Failure With Preserved Ejection Fraction
- (2019) Omar F. AbouEzzeddine et al. Circulation-Heart Failure
- Is Heart Failure with Preserved Ejection Fraction a Kidney Disorder?
- (2019) Kevin S. Shah et al. CURRENT HYPERTENSION REPORTS
- Optimizing The Management of Obese HFpEF Phenotype: Can We Mind Both The Heart and The Kidney?
- (2019) Bharathi Upadhya et al. JOURNAL OF CARDIAC FAILURE
- Myocardial Phosphodiesterases and their Role in cGMP Regulation
- (2019) Brittany Dunkerly-Eyring et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Prior Heart Failure Hospitalization, Clinical Outcomes, and Response to Sacubitril/Valsartan Compared with Valsartan in HFpEF
- (2019) Muthiah Vaduganathan et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
- (2019) Domenico D’Amario et al. Frontiers in Physiology
- Endothelium‐dependent and independent coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction
- (2019) Jeong Hoon Yang et al. EUROPEAN JOURNAL OF HEART FAILURE
- A new algorithm for optimization of rate‐adaptive pacing improves exercise tolerance in patients with HFpEF
- (2019) Maria Serova et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- Heart Failure with Reduced Ejection Fraction (HFrEF) and Preserved Ejection Fraction (HFpEF): The Diagnostic Value of Circulating MicroRNAs
- (2019) Yei-Tsung Chen et al. Cells
- Effect of Spironolactone on Myocardial Fibrosis and Other Clinical Variables in Patients with Hypertrophic Cardiomyopathy
- (2018) Martin S. Maron et al. AMERICAN JOURNAL OF MEDICINE
- Characterization of a mouse model of obesity-related fibrotic cardiomyopathy that recapitulates features of human Heart Failure with Preserved Ejection Fraction
- (2018) Linda Alex et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Heart Failure with Preserved Ejection Fraction
- (2018) James D. Gladden et al. Annual Review of Medicine
- Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening
- (2018) Oana Sorop et al. CARDIOVASCULAR RESEARCH
- A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction
- (2018) Yogesh N. V. Reddy et al. CIRCULATION
- Diabetes-Induced Cardiomyocyte Passive Stiffening Is Caused by Impaired Insulin-Dependent Titin Modification and Can Be Modulated by Neuregulin-1Novelty and Significance
- (2018) Anna-Eliane Hopf et al. CIRCULATION RESEARCH
- Diabetic Cardiomyopathy
- (2018) Guanghong Jia et al. CIRCULATION RESEARCH
- Mortality associated with heart failure with preserved vs. reduced ejection fraction in a prospective international multi-ethnic cohort study
- (2018) Carolyn S P Lam et al. EUROPEAN HEART JOURNAL
- Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease
- (2018) Thomas M Gorter et al. EUROPEAN HEART JOURNAL
- Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial
- (2018) Susana Ravassa et al. EUROPEAN JOURNAL OF HEART FAILURE
- Heart failure with preserved ejection fraction: controversies, challenges and future directions
- (2018) Rosita Zakeri et al. HEART
- Mechanisms of the Improvement in Peak VO 2 With Exercise Training in Heart Failure With Reduced or Preserved Ejection Fraction
- (2018) Wesley J. Tucker et al. Heart Lung and Circulation
- Captopril Attenuates Cardiovascular and Renal Disease in a Rat Model of Heart Failure With Preserved Ejection Fraction
- (2018) Eman M. Salah et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
- (2018) Xing Fu et al. JOURNAL OF CLINICAL INVESTIGATION
- Defining the molecular signatures of human right heart failure
- (2018) Jordan L. Williams et al. LIFE SCIENCES
- Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction
- (2018) Natasha Fillmore et al. MOLECULAR MEDICINE
- Nitric oxide signalling in cardiovascular health and disease
- (2018) Charlotte Farah et al. Nature Reviews Cardiology
- Mechanisms of physiological and pathological cardiac hypertrophy
- (2018) Michinari Nakamura et al. Nature Reviews Cardiology
- Cardiac metabolism — A promising therapeutic target for heart failure
- (2018) Hannah Noordali et al. PHARMACOLOGY & THERAPEUTICS
- Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism
- (2018) Mark Y. Jeong et al. Science Translational Medicine
- High Right Ventricular Stroke Work Index Is Associated with Worse Kidney Function in Patients with Heart Failure with Preserved Ejection Fraction
- (2018) Napatt Kanjanahattakij et al. CardioRenal Medicine
- Pro‐Inflammatory Biomarkers in Stable Versus Acutely Decompensated Heart Failure With Preserved Ejection Fraction
- (2018) Abraham Abernethy et al. Journal of the American Heart Association
- Association of APOL1 With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women
- (2018) Nora Franceschini et al. JAMA Cardiology
- Association of Cardiovascular Biomarkers With Incident Heart Failure With Preserved and Reduced Ejection Fraction
- (2018) Rudolf A. de Boer et al. JAMA Cardiology
- IL-1 Blockade in Patients With Heart Failure With Preserved Ejection Fraction
- (2018) Benjamin W. Van Tassell et al. Circulation-Heart Failure
- Heart failure with preserved ejection fraction in Asia
- (2018) Jasper Tromp et al. EUROPEAN JOURNAL OF HEART FAILURE
- Effects of Endurance Training on Detrimental Structural, Cellular, and Functional Alterations in Skeletal Muscles of Heart Failure With Preserved Ejection Fraction
- (2018) T. Scott Bowen et al. JOURNAL OF CARDIAC FAILURE
- High-sensitivity C-reactive protein in heart failure with preserved ejection fraction
- (2018) Hilary M. DuBrock et al. PLoS One
- Pulmonary vascular disease in the setting of heart failure with preserved ejection fraction
- (2018) Andrea R. Levine et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Plasma levels of heart failure biomarkers are primarily a reflection of extracardiac production
- (2018) Weijie Du et al. Theranostics
- Weighty Matters in HFpEF and Aging ∗
- (2018) Daniel E. Forman et al. JACC-Heart Failure
- Randomized Evaluation of Heart Failure With Preserved Ejection Fraction Patients With Acute Heart Failure and Dopamine
- (2018) Kavita Sharma et al. JACC-Heart Failure
- Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction
- (2018) Masaru Obokata et al. EUROPEAN HEART JOURNAL
- Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction
- (2018) Barry A. Borlaug et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Coronary microvascular dysfunction and future risk of heart failure with preserved ejection fraction
- (2017) Viviany R Taqueti et al. EUROPEAN HEART JOURNAL
- Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) study
- (2017) Burkert Pieske et al. EUROPEAN HEART JOURNAL
- The prognostic value of highly sensitive cardiac troponin assays for adverse events in men and women with stable heart failure and a preserved vs. reduced ejection fraction
- (2017) Aisha Gohar et al. EUROPEAN JOURNAL OF HEART FAILURE
- Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology
- (2017) Thomas M. Gorter et al. EUROPEAN JOURNAL OF HEART FAILURE
- Effect of ivabradine in patients with heart failure with preserved ejection fraction: the EDIFY randomized placebo-controlled trial
- (2017) Michel Komajda et al. EUROPEAN JOURNAL OF HEART FAILURE
- Skeletal muscle inflammation and insulin resistance in obesity
- (2017) Huaizhu Wu et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction
- (2017) Xiaochen He et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The diabetic heart utilizes ketone bodies as an energy source
- (2017) Yuji Mizuno et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Spironolactone Metabolites in TOPCAT — New Insights into Regional Variation
- (2017) Simon de Denus et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bariatric Surgery-Induced Cardiac and Lipidomic Changes in Obesity-Related Heart Failure with Preserved Ejection Fraction
- (2017) Deana Mikhalkova et al. Obesity
- Cardiac oxidative stress in diabetes: Mechanisms and therapeutic potential
- (2017) Alyssa Faria et al. PHARMACOLOGY & THERAPEUTICS
- T cell costimulation blockade blunts pressure overload-induced heart failure
- (2017) Marinos Kallikourdis et al. Nature Communications
- Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection FractionCLINICAL PERSPECTIVE
- (2017) Camilla Hage et al. Circulation-Cardiovascular Genetics
- Heart Failure with Preserved Ejection Fraction and Future Pharmacological Strategies: a Glance in the Crystal Ball
- (2017) Carsten Tschöpe et al. Current Cardiology Reports
- Factors Associated With and Prognostic Implications of Cardiac Troponin Elevation in Decompensated Heart Failure With Preserved Ejection Fraction
- (2017) Ambarish Pandey et al. JAMA Cardiology
- Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy
- (2017) Nicolas Diguet et al. CIRCULATION
- Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure])
- (2017) Ted Feldman et al. CIRCULATION
- Global Pulmonary Vascular Remodeling in Pulmonary Hypertension Associated With Heart Failure and Preserved or Reduced Ejection Fraction
- (2017) Ahmed U. Fayyaz et al. CIRCULATION
- Mitochondrial NAD+/NADH Redox State and Diabetic Cardiomyopathy
- (2017) Jessica M. Berthiaume et al. ANTIOXIDANTS & REDOX SIGNALING
- Diagnostic significance of serum galectin-3 levels in heart failure with preserved ejection fraction
- (2016) Veli Polat et al. ACTA CARDIOLOGICA
- Myocardial steatosis as a possible mechanistic link between diastolic dysfunction and coronary microvascular dysfunction in women
- (2016) Janet Wei et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal
- (2016) Olurotimi O. Mesubi et al. CARDIOVASCULAR RESEARCH
- Normalization of NAD+Redox Balance as a Therapy for Heart FailureClinical Perspective
- (2016) Chi Fung Lee et al. CIRCULATION
- SIRT3-AMPK Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)
- (2016) Yen-Chun Lai et al. CIRCULATION
- The Failing Heart Relies on Ketone Bodies as a Fuel
- (2016) Gregory Aubert et al. CIRCULATION
- CV Protection in the EMPA-REG OUTCOME Trial: A “Thrifty Substrate” Hypothesis
- (2016) Ele Ferrannini et al. DIABETES CARE
- Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction
- (2016) Uwe Primessnig et al. EUROPEAN JOURNAL OF HEART FAILURE
- Redox signaling in the cardiomyocyte: From physiology to failure
- (2016) Celio X.C. Santos et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Vascular and Microvascular Endothelial Function in Heart Failure With Preserved Ejection Fraction
- (2016) Sylvestre Maréchaux et al. JOURNAL OF CARDIAC FAILURE
- Effects of Milrinone on Rest and Exercise Hemodynamics in Heart Failure With Preserved Ejection Fraction
- (2016) David M. Kaye et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The HFpEF Obesity Phenotype
- (2016) Dalane W. Kitzman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure
- (2016) Wynn G. Hunter et al. Journal of the American Heart Association
- Skeletal Muscle Mitochondrial Content, Oxidative Capacity, and Mfn2 Expression Are Reduced in Older Patients With Heart Failure and Preserved Ejection Fraction and Are Related to Exercise Intolerance
- (2016) Anthony J.A. Molina et al. JACC-Heart Failure
- Impaired Pulmonary Diffusion in Heart Failure With Preserved Ejection Fraction
- (2016) Thomas P. Olson et al. JACC-Heart Failure
- Myocardial Microvascular Inflammatory Endothelial Activation in Heart Failure With Preserved Ejection Fraction
- (2016) Constantijn Franssen et al. JACC-Heart Failure
- Diffusion Capacity and Mortality in Patients With Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
- (2016) Marius M. Hoeper et al. JACC-Heart Failure
- Exercise training in chronic heart failure: improving skeletal muscle O2 transport and utilization
- (2015) Daniel M. Hirai et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction
- (2015) Michael Schwarzl et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The cGMP/PKG pathway as a common mediator of cardioprotection: translatability and mechanism
- (2015) Javier Inserte et al. BRITISH JOURNAL OF PHARMACOLOGY
- Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction
- (2015) Thenappan Thenappan et al. CANADIAN JOURNAL OF CARDIOLOGY
- Effect of Selective Heart Rate Slowing in Heart Failure With Preserved Ejection FractionCLINICAL PERSPECTIVE
- (2015) Nikhil Pal et al. CIRCULATION
- Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction: Contributions of Collagen and Titin
- (2015) M. R. Zile et al. CIRCULATION
- Upregulation of MG53 Induces Diabetic Cardiomyopathy Through Transcriptional Activation of Peroxisome Proliferation-Activated Receptor
- (2015) F. Liu et al. CIRCULATION
- Role of biomarkers in cardiac structure phenotyping in heart failure with preserved ejection fraction: critical appraisal and practical use
- (2015) Emilia D'Elia et al. EUROPEAN JOURNAL OF HEART FAILURE
- Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction
- (2015) S. Sanders-van Wijk et al. EUROPEAN JOURNAL OF HEART FAILURE
- Circulating microRNAs in heart failure with reduced and preserved left ventricular ejection fraction
- (2015) Lee Lee Wong et al. EUROPEAN JOURNAL OF HEART FAILURE
- Growth differentiation factor 15 in heart failure with preserved vs. reduced ejection fraction
- (2015) Michelle M.Y. Chan et al. EUROPEAN JOURNAL OF HEART FAILURE
- Evidence of microvascular dysfunction in heart failure with preserved ejection fraction
- (2015) Joshua F Lee et al. HEART
- Determinants of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction
- (2015) Mark J. Haykowsky et al. JOURNAL OF APPLIED PHYSIOLOGY
- Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
- (2015) Dong I. Lee et al. NATURE
- Myocardial pressure overload induces systemic inflammation through endothelial cell IL-33
- (2015) Wei-Yu Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction
- (2015) Beshay N. Zordoky et al. PLoS One
- Skeletal Muscle Composition and Its Relation to Exercise Intolerance in Older Patients With Heart Failure and Preserved Ejection Fraction
- (2014) Mark J. Haykowsky et al. AMERICAN JOURNAL OF CARDIOLOGY
- Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction
- (2014) Dalane W. Kitzman et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- CD4 + T Cells Promote the Transition From Hypertrophy to Heart Failure During Chronic Pressure Overload
- (2014) Fanny Laroumanie et al. CIRCULATION
- Right Ventricular Function in Heart Failure With Preserved Ejection Fraction
- (2014) Selma F. Mohammed et al. CIRCULATION
- Resting Ventricular–Vascular Function and Exercise Capacity in Heart Failure With Preserved Ejection Fraction
- (2014) Selma F. Mohammed et al. Circulation-Heart Failure
- Right heart dysfunction in heart failure with preserved ejection fraction
- (2014) Vojtech Melenovsky et al. EUROPEAN HEART JOURNAL
- PDE5 inhibitor efficacy is estrogen dependent in female heart disease
- (2014) Hideyuki Sasaki et al. JOURNAL OF CLINICAL INVESTIGATION
- Cardiovascular Phenotype in HFpEF Patients With or Without Diabetes
- (2014) Brian R. Lindman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Spironolactone for Heart Failure with Preserved Ejection Fraction
- (2014) Bertram Pitt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
- (2014) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Circulating Levels of Tumor Necrosis Factor-Alpha Receptor 2 Are Increased in Heart Failure with Preserved Ejection Fraction Relative to Heart Failure with Reduced Ejection Fraction: Evidence for a Divergence in Pathophysiology
- (2014) Brendan N. Putko et al. PLoS One
- Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities
- (2014) Michele Cavalera et al. Translational Research
- Preconditioning with soluble guanylate cyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice
- (2013) Walter Z. Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure
- (2013) Georgios Karamanlidis et al. Cell Metabolism
- Protein Kinase G Positively Regulates Proteasome-Mediated Degradation of Misfolded Proteins
- (2013) Mark J. Ranek et al. CIRCULATION
- Cardiac Metabolism in Heart Failure
- (2013) Torsten Doenst et al. CIRCULATION RESEARCH
- Mechanisms of Altered Ca 2+ Handling in Heart Failure
- (2013) Min Luo et al. CIRCULATION RESEARCH
- Plasma Free Fatty Acids and Risk of Heart Failure
- (2013) Luc Djoussé et al. Circulation-Heart Failure
- Myocardial Titin Hypophosphorylation Importantly Contributes to Heart Failure With Preserved Ejection Fraction in a Rat Metabolic Risk Model
- (2013) Nazha Hamdani et al. Circulation-Heart Failure
- Left Ventricular Mass and Hypertrophy by Echocardiography and Cardiac Magnetic Resonance: The Multi-Ethnic Study of Atherosclerosis
- (2013) Anderson C. Armstrong et al. ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
- Galectin-3 in heart failure with preserved ejection fraction
- (2013) Rudolf A. de Boer et al. EUROPEAN JOURNAL OF HEART FAILURE
- Increased cGMP promotes healthy expansion and browning of white adipose tissue
- (2013) Michaela M. Mitschke et al. FASEB JOURNAL
- Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction
- (2013) Margaret M. Redfield et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II
- (2013) Juan Shi et al. JOURNAL OF PHYSIOLOGY-LONDON
- A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
- (2013) Walter J. Paulus et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Impaired Aerobic Capacity and Physical Functional Performance in Older Heart Failure Patients With Preserved Ejection Fraction: Role of Lean Body Mass
- (2013) M. J. Haykowsky et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A heart–adipose tissue connection in the regulation of energy metabolism
- (2013) Sheila Collins Nature Reviews Endocrinology
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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- (2010) Dirk Westermann et al. Circulation-Heart Failure
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- (2010) Arantxa González et al. HYPERTENSION
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- (2010) Sadhana A. Samant et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Barry A. Borlaug et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2010) S. H. Francis et al. PHARMACOLOGICAL REVIEWS
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- (2009) Nina Kaludercic et al. CIRCULATION RESEARCH
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- (2009) Thanh Trung Phan et al. Circulation-Heart Failure
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- (2009) Norimichi Koitabashi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2009) Barry A. Borlaug et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2009) Thanh T. Phan et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2009) N. Sawada et al. MOLECULAR AND CELLULAR BIOLOGY
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- (2008) Tetsuro Ago et al. CELL
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- (2008) Takeshi Tokudome et al. CIRCULATION
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- (2008) Ying Xia et al. HISTOCHEMISTRY AND CELL BIOLOGY
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- (2007) Loek van Heerebeek et al. CIRCULATION
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