Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1

(2020) Jasenko Zivanov et al.   IUCrJ

Cryo-EM structures of inactive and active GABAB receptor

(2020) Chunyou Mao et al.   CELL RESEARCH

Mitigating local over-fitting during single particle reconstruction with SIDESPLITTER

(2020) Kailash Ramlaul et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cryo-EM structures of GPCRs coupled to Gs, Gi and Go

(2019) Javier García-Nafría et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Molecular basis for high-affinity agonist binding in GPCRs

(2019) Tony Warne et al.   SCIENCE

Cryo-EM structure of the native rhodopsin dimer in nanodiscs

(2019) Dorothy Yanling Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Molecular Basis of G Protein–Coupled Receptor Activation

(2018) William I. Weis et al.   Annual Review of Biochemistry

Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

(2018) Neil Andrew Brown et al.   Nature Microbiology

Advanced Data Acquisition From Electron Microscopes With SerialEM

(2018) David N. Mastronarde   MICROSCOPY AND MICROANALYSIS

Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go

(2018) Javier García-Nafría et al.   NATURE

A Local Agreement Filtering Algorithm for Transmission EM Reconstructions

(2018) Kailash Ramlaul et al.   JOURNAL OF STRUCTURAL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Recent developments in the CCP-EM software suite

(2017) Tom Burnley et al.   Acta Crystallographica Section D-Structural Biology

AceDRG: a stereochemical description generator for ligands

(2017) Fei Long et al.   Acta Crystallographica Section D-Structural Biology

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

(2017) Rony Nehmé et al.   PLoS One

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor

(2016) Richard B Cooley et al.   eLife

Cryo-EM single particle analysis with the Volta phase plate

(2016) Radostin Danev et al.   eLife

IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly

(2016) Javier García-Nafría et al.   Scientific Reports

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

Universal allosteric mechanism for Gα activation by GPCRs

(2015) Tilman Flock et al.   NATURE

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Generic GPCR residue numbers – aligning topology maps while minding the gaps

(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AliView: a fast and lightweight alignment viewer and editor for large datasets

(2014) Anders Larsson   BIOINFORMATICS

Guanine Nucleotide-binding Protein (Gα) Endocytosis by a Cascade of Ubiquitin Binding Domain Proteins Is Required for Sustained Morphogenesis and Proper Mating in Yeast

(2014) Gauri Dixit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Characterization of Protein Cavities within Molecular Simulation Trajectories: trj_cavity

(2014) Teresa Paramo et al.   Journal of Chemical Theory and Computation

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Critical analysis of the successes and failures of homology models of G protein-coupled receptors

(2013) Supriyo Bhattacharya et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Receptor oligomerization: from early evidence to current understanding in class B GPCRs

(2013) Stephanie Y. L. Ng et al.   Frontiers in Endocrinology

Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR

(2011) Kyeong-Man Kim et al.   PHARMACOLOGICAL RESEARCH

Activation mechanism of the  2-adrenergic receptor

(2011) R. O. Dror et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation

(2009) Nigel W. Moriarty et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of Amino Acids at Two Dimer Interface Regions of the α-Factor Receptor (Ste2)

(2009) Hong X. Wang et al.   BIOCHEMISTRY

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Molecular simulation of multistate peptide dynamics: A comparison between microsecond timescale sampling and multiple shorter trajectories

(2008) Luca Monticelli et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY