The Interplay of ABC Transporters in Aβ Translocation and Cholesterol Metabolism: Implicating Their Roles in Alzheimer’s Disease
出版年份 2020 全文链接
标题
The Interplay of ABC Transporters in Aβ Translocation and Cholesterol Metabolism: Implicating Their Roles in Alzheimer’s Disease
作者
关键词
-
出版物
MOLECULAR NEUROBIOLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-11-20
DOI
10.1007/s12035-020-02211-x
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
- (2019) Arne De Roeck et al. ACTA NEUROPATHOLOGICA
- Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation
- (2018) Julien Saint-Pol et al. JOURNAL OF ALZHEIMERS DISEASE
- ABCG2- and ABCG4-Mediated Efflux of Amyloid-β Peptide 1-40 at the Mouse Blood-Brain Barrier
- (2018) Tuan Minh Do et al. JOURNAL OF ALZHEIMERS DISEASE
- The Role of ABCA1 Gene Sequence Variants on Risk of Alzheimer's Disease
- (2018) Michelle K. Lupton et al. JOURNAL OF ALZHEIMERS DISEASE
- Interaction Between Two Cholesterol Metabolism Genes Influences Memory: Findings from the Wisconsin Registry for Alzheimer's Prevention
- (2018) Corinne D. Engelman et al. JOURNAL OF ALZHEIMERS DISEASE
- ABC Transporters Are Key Players in Alzheimer’s Disease
- (2017) Cátia D. Pereira et al. JOURNAL OF ALZHEIMERS DISEASE
- Role of ABC transporters in the pathology of Alzheimer’s disease
- (2017) Yan Zhao et al. REVIEWS IN THE NEUROSCIENCES
- Pharmacological Treatment of Alzheimer Disease
- (2017) Fadi Massoud et al. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
- Impact of 27-Hydroxycholesterol on Amyloid-β Peptide Production and ATP-Binding Cassette Transporter Expression in Primary Human Neurons
- (2017) Woojin Scott Kim et al. JOURNAL OF ALZHEIMERS DISEASE
- Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein
- (2017) Pietra Candela et al. JOURNAL OF ALZHEIMERS DISEASE
- Increased ATP-Binding Cassette Transporter A1 Expression in Alzheimer's Disease Hippocampal Neurons
- (2017) Woojin Scott Kim et al. JOURNAL OF ALZHEIMERS DISEASE
- ABCA7 Genotypes Confer Alzheimer’s Disease Risk by Modulating Amyloid-β Pathology
- (2016) Qing-Fei Zhao et al. JOURNAL OF ALZHEIMERS DISEASE
- ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain
- (2016) YuHong Fu et al. JOURNAL OF ALZHEIMERS DISEASE
- Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models
- (2016) Michelle Bamji-Mirza et al. JOURNAL OF ALZHEIMERS DISEASE
- ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology
- (2016) Nobutaka Sakae et al. JOURNAL OF NEUROSCIENCE
- A 40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway
- (2016) A. M. S. Hartz et al. JOURNAL OF NEUROSCIENCE
- ABCG1 and ABCG4 Suppress γ-Secretase Activity and Amyloid β Production
- (2016) Osamu Sano et al. PLoS One
- ABC Transporter Subfamily D: Distinct Differences in Behavior between ABCD1–3 and ABCD4 in Subcellular Localization, Function, and Human Disease
- (2016) Kosuke Kawaguchi et al. Biomed Research International
- Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
- (2015) Liv Tybjærg Nordestgaard et al. Alzheimers & Dementia
- ABC transporter research: going strong 40 years on
- (2015) F. L. Theodoulou et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
- (2015) Hisham Qosa et al. BRAIN RESEARCH
- The ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene
- (2015) Warren Davis Jr. Current Alzheimer Research
- Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes
- (2015) Bing Ye et al. GLIA
- ATP-binding Cassette Transporter A7 (ABCA7) Loss of Function Alters Alzheimer Amyloid Processing
- (2015) Kanayo Satoh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thermodynamics of ABC transporters
- (2015) Xuejun C. Zhang et al. Protein & Cell
- Cerebral ABC Transporter-common Mechanisms May Modulate Neurodegenerative Diseases and Depression in Elderly Subjects
- (2014) Jens Pahnke et al. ARCHIVES OF MEDICAL RESEARCH
- Structural diversity of ABC transporters
- (2014) Josy ter Beek et al. JOURNAL OF GENERAL PHYSIOLOGY
- Aβ1–42 reduces P-glycoprotein in the blood–brain barrier through RAGE–NF-κB signaling
- (2014) R Park et al. Cell Death & Disease
- Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences
- (2014) Michelle Mielke et al. Clinical Epidemiology
- Exploring Myelin Dysfunction in Multiple System Atrophy
- (2014) Joanna H. Wong et al. Experimental Neurobiology
- A Complex Association of ABCA7 Genotypes With Sporadic Alzheimer Disease in Chinese Han Population
- (2013) Li-Hua Liu et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study
- (2013) Barbara Breitenstein et al. CNS SPECTRUMS
- Reduced Alzheimer’s Disease Pathology by St. John’s Wort Treatment is Independent of Hyperforin and Facilitated by ABCC1 and Microglia Activation in Mice
- (2013) Jacqueline Hofrichter et al. Current Alzheimer Research
- ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status
- (2013) Jared B. Vasquez et al. NEUROSCIENCE LETTERS
- Genetic Susceptibility for Alzheimer Disease Neuritic Plaque Pathology
- (2013) Joshua M. Shulman et al. JAMA Neurology
- Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease
- (2012) Alaa H. Abuznait et al. ACS Chemical Neuroscience
- Pregnane X receptor upregulates ABC-transporter Abcg2 and Abcb1 at the blood-brain barrier
- (2012) Julia Lemmen et al. BRAIN RESEARCH
- P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender
- (2012) Daniëlle M. E. van Assema et al. MOLECULAR IMAGING AND BIOLOGY
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- ABC Transporters and the Alzheimer’s Disease Enigma
- (2012) Andrea Wolf et al. Frontiers in Psychiatry
- Blood–brain barrier P-glycoprotein function in Alzheimer's disease
- (2011) Daniëlle M. E. van Assema et al. BRAIN
- Down-regulation of the ATP-binding Cassette Transporter 2 (Abca2) Reduces Amyloid-β Production by Altering Nicastrin Maturation and Intracellular Localization
- (2011) Vasiliki Michaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice
- (2011) Markus Krohn et al. JOURNAL OF CLINICAL INVESTIGATION
- Amyloid-β peptide(1-40) elimination from cerebrospinal fluid involves low-density lipoprotein receptor-related protein 1 at the blood-cerebrospinal fluid barrier
- (2011) Masachika Fujiyoshi et al. JOURNAL OF NEUROCHEMISTRY
- Critical Role of Astroglial Apolipoprotein E and Liver X Receptor- Expression for Microglial A Phagocytosis
- (2011) D. Terwel et al. JOURNAL OF NEUROSCIENCE
- Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease
- (2011) Alaa H. Abuznait et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
- (2011) Ramzi Shawahna et al. MOLECULAR PHARMACEUTICS
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
- (2011) Paul Hollingworth et al. NATURE GENETICS
- ATP-Binding Cassette Transporters and Their Roles in Protecting the Brain
- (2011) Ayman ElAli et al. NEUROSCIENTIST
- Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus
- (2010) Afia Akram et al. BRAIN RESEARCH
- ABC efflux transporters in brain vasculature of Alzheimer's subjects
- (2010) Hasini C. Wijesuriya et al. BRAIN RESEARCH
- The ATP-Binding Cassette Transporter-2 (ABCA2) Increases Endogenous Amyloid Precursor Protein Expression and Abeta Fragment Generation
- (2010) W. Davis Current Alzheimer Research
- ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice
- (2010) James J. Donkin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer’s disease
- (2010) Shanshan Shen et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis
- (2010) S. W. Pimplikar et al. JOURNAL OF NEUROSCIENCE
- Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid- in a Mouse Model of Alzheimer's Disease
- (2010) A. M. S. Hartz et al. MOLECULAR PHARMACOLOGY
- An investigation into the role of P-glycoprotein in Alzheimer's disease lesion pathogenesis
- (2010) Brian Jeynes et al. NEUROSCIENCE LETTERS
- Decreased Clearance of CNS -Amyloid in Alzheimer's Disease
- (2010) K. G. Mawuenyega et al. SCIENCE
- Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease
- (2009) Robert D. Bell et al. ACTA NEUROPATHOLOGICA
- Interaction between HMGCR and ABCA1 cholesterol-related genes modulates Alzheimer's disease risk
- (2009) Eloy Rodríguez-Rodríguez et al. BRAIN RESEARCH
- P-gp Transporter and its Role in Neurodegenerative Diseases
- (2009) Simona Rapposelli et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- A survey ofABCA1sequence variation confirms association with dementia
- (2009) Chandra A. Reynolds et al. HUMAN MUTATION
- P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β
- (2009) Leon M Tai et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood-Brain Barrier for A 1-40 Peptides
- (2009) H. Xiong et al. JOURNAL OF NEUROSCIENCE
- Liver X receptor activation restores memory in aged AD mice without reducing amyloid
- (2009) Tim Vanmierlo et al. NEUROBIOLOGY OF AGING
- ABC Transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) Expression in the Developing Human CNS
- (2009) M. Daood et al. NEUROPEDIATRICS
- The Precapillary Segment of the Blood-Brain Barrier and Its Relation to Perivascular Drainage in Alzheimer's Disease and Small Vessel Disease.
- (2009) Dietmar R. Thal TheScientificWorldJOURNAL
- The blood-brain barrier in brain homeostasis and neurological diseases
- (2008) Nicolas Weiss et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer's brain
- (2008) Yoshinari Uehara et al. BRAIN RESEARCH
- Clinico-Pathologic Function of Cerebral ABC Transporters – Implications for the Pathogenesis of Alzheimers Disease
- (2008) Jens Pahnke et al. Current Alzheimer Research
- A Comprehensive in Vitro and in Silico Analysis of Antibiotics That Activate Pregnane X Receptor and Induce CYP3A4 in Liver and Intestine
- (2008) K. Yasuda et al. DRUG METABOLISM AND DISPOSITION
- Regulation of ABC membrane transporters in glial cells: Relevance to the pharmacotherapy of brain HIV-1 infection
- (2008) Patrick T. Ronaldson et al. GLIA
- Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA
- (2008) A. L. Bartels et al. JOURNAL OF NEURAL TRANSMISSION
- ATP-binding cassette transporter A7 regulates processing of amyloid precursor proteinin vitro
- (2008) Sharon L. Chan et al. JOURNAL OF NEUROCHEMISTRY
- Role of ATP-binding cassette transporters in brain lipid transport and neurological disease
- (2008) Woojin Scott Kim et al. JOURNAL OF NEUROCHEMISTRY
- Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression
- (2008) Manfred Uhr et al. NEURON
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain
- (2007) Nan Wang et al. FASEB JOURNAL
- ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier
- (2007) Shin-ichi Akanuma et al. NEUROCHEMISTRY INTERNATIONAL
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