A positive feedback loop between TAZ and miR-942-3p modulates proliferation, angiogenesis, epithelial-mesenchymal transition process, glycometabolism and ROS homeostasis in human bladder cancer

Oncogenic role of MIR516A in human bladder cancer was mediated by its attenuating PHLPP2 expression and BECN1-dependent autophagy

(2020) Honglei Jin et al.   Autophagy

miR‐190b promotes tumor growth and metastasis via suppressing NLRC3 in bladder carcinoma

(2020) Zhaohui Chen et al.   FASEB JOURNAL

Sodium butyrate inhibits migration and induces AMPK‐mTOR pathway‐dependent autophagy and ROS‐mediated apoptosis via the miR‐139‐5p/Bmi‐1 axis in human bladder cancer cells

(2020) Feifan Wang et al.   FASEB JOURNAL

LncRNA LUADT1 Promotes Oral Squamous Cell Carcinoma Cell Proliferation by Regulating miR-34a/GAS1 Axis

(2020) Lirong Gao et al.   Cancer Management and Research

BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

(2020) H. H. Pulkkinen et al.   ANGIOGENESIS

SIRT1 promotes GLUT1 expression and bladder cancer progression via regulation of glucose uptake

(2019) Jia Chen et al.   Human Cell

TAZ sensitizes EGFR wild-type non-small-cell lung cancer to gefitinib by promoting amphiregulin transcription

(2019) Weiwei Yuan et al.   Cell Death & Disease

YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells

(2019) Shannon M. White et al.   DEVELOPMENTAL CELL

LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation

(2019) Caitlin M. Braitsch et al.   PLOS BIOLOGY

Role of Hippo Pathway-YAP/TAZ Signaling in Angiogenesis

(2019) Gandhi T. K. Boopathy et al.   Frontiers in Cell and Developmental Biology

Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways

(2019) Hanna Karvonen et al.   Cells

FOXJ1 promotes bladder cancer cell growth and regulates Warburg effect

(2018) Shaozhong Xian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth

(2018) Laura Sánchez-Hernández et al.   GENE THERAPY

Sodium Butyrate Inhibits Colorectal Cancer Cell Migration by Downregulating Bmi-1 Through Enhanced miR-200c Expression

(2018) Zhiyao Xu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Hippo pathway in normal development and cancer

(2018) Marcello Maugeri-Saccà et al.   PHARMACOLOGY & THERAPEUTICS

EMT: Mechanisms and therapeutic implications

(2018) Mohini Singh et al.   PHARMACOLOGY & THERAPEUTICS

Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors

(2018) et al.   Cancers

Effects of Biguanides on Growth and Glycolysis of Bladder and Colon Cancer Cells

(2018) MICHAEL A. LEA et al.   ANTICANCER RESEARCH

Interplay between YAP/TAZ and Metabolism

(2018) Ja Hyun Koo et al.   Cell Metabolism

The role of YAP/TAZ activity in cancer metabolic reprogramming

(2018) Xiaodong Zhang et al.   Molecular Cancer

miR-665 promotes hepatocellular carcinoma cell migration, invasion, and proliferation by decreasing Hippo signaling through targeting PTPRB

(2018) Yuanchang Hu et al.   Cell Death & Disease

Microglia induces Gas1 expression in human brain tumor-initiating cells to reduce tumorigenecity

(2018) Susobhan Sarkar et al.   Scientific Reports

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

(2018) Andrew G Cox et al.   EMBO JOURNAL

miR-103 promotes the metastasis and EMT of hepatocellular carcinoma by directly inhibiting LATS2

(2018) Li-Li Han et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

(2018) Iván M. Moya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

(2017) Sebastien Antoni et al.   EUROPEAN UROLOGY

YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation

(2017) Jongshin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

(2017) Kimberly C. Lin et al.   NATURE CELL BIOLOGY

Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma

(2017) André Luis Giacometti Conceição et al.   ONCOLOGY REPORTS

Regulation of the Hippo Pathway Transcription Factor TEAD

(2017) Kimberly C. Lin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bladder cancer

(2017) Oner Sanli et al.   Nature Reviews Disease Primers

WT1 is involved in the Akt-JNK pathway dependent autophagy through directly regulating Gas1 expression in human osteosarcoma cells

(2016) Hao Mo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

YAP/TAZ at the Roots of Cancer

(2016) Francesca Zanconato et al.   CANCER CELL

Epithelial–mesenchymal transition (EMT) and metastasis: yes, no, maybe?

(2016) Maren Diepenbruck et al.   CURRENT OPINION IN CELL BIOLOGY

Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression

(2016) Yuhao Shi et al.   DEVELOPMENTAL CELL

Gender and Bladder Cancer: A Collaborative Review of Etiology, Biology, and Outcomes

(2016) Jakub Dobruch et al.   EUROPEAN UROLOGY

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma

(2016) Q. Li et al.   MOLECULAR CANCER RESEARCH

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Closing the Gender Gap: Can We Improve Bladder Cancer Survival in Women? - A Systematic Review of Diagnosis, Treatment and Outcomes

(2016) Frances Burge et al.   UROLOGIA INTERNATIONALIS

Gender-related differences in urothelial carcinoma of the bladder: a population-based study from the Swedish National Registry of Urinary Bladder Cancer

(2016) Andreas Thorstenson et al.   Scandinavian Journal of Urology

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

The Hippo transducer TAZ promotes epithelial to mesenchymal transition and cancer stem cell maintenance in oral cancer

(2015) Zhongwu Li et al.   Molecular Oncology

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

A soluble form of GAS1 inhibits tumor growth and angiogenesis in a triple negative breast cancer model

(2014) Adriana Jiménez et al.   EXPERIMENTAL CELL RESEARCH

MiR-942 Mediates Hepatitis C Virus-Induced Apoptosis via Regulation of ISG12a

(2014) Darong Yang et al.   PLoS One

MiR-34a targets GAS1 to promote cell proliferation and inhibit apoptosis in papillary thyroid carcinoma via PI3K/Akt/Bad pathway

(2013) Yanfei Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Aberrant expression of microRNAs in bladder cancer

(2013) Hirofumi Yoshino et al.   Nature Reviews Urology

Lack of progress in bladder cancer—what are the obstacles?

(2012) Mark S. Soloway   Nature Reviews Urology

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

MicroRNAs as potential cancer therapeutics

(2009) P Trang et al.   ONCOGENE

TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

(2008) Q.-Y. Lei et al.   MOLECULAR AND CELLULAR BIOLOGY