Structural basis for multifunctional roles of human Ints3 C-terminal domain

The roles of RNA in DNA double-strand break repair

(2020) Aldo S. Bader et al.   BRITISH JOURNAL OF CANCER

Structures and regulations of ATM and ATR, master kinases in genome integrity

(2020) Rhys M Williams et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms

(2020) Meredith Corley et al.   MOLECULAR CELL

The PSIPRED Protein Analysis Workbench: 20 years on

(2019) Daniel W A Buchan et al.   NUCLEIC ACIDS RESEARCH

Benchmarking fold detection by DaliLite v.5

(2019) Liisa Holm   BIOINFORMATICS

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair

(2018) Aleem Syed et al.   Annual Review of Biochemistry

Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module

(2018) Todd R Albrecht et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of DNA damage, repair, and mutagenesis

(2017) Nimrat Chatterjee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

HEAT repeats – versatile arrays of amphiphilic helices working in crowded environments?

(2016) Shige H. Yoshimura et al.   JOURNAL OF CELL SCIENCE

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of ATM Activation

(2015) Tanya T. Paull   Annual Review of Biochemistry

Viral ssRNAs Are Indeed Compact

(2015) A. Ben-Shaul et al.   BIOPHYSICAL JOURNAL

Crystal structure of the V(D)J recombinase RAG1–RAG2

(2015) Min-Sung Kim et al.   NATURE

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation

(2014) Zuyao Ni et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA

(2014) Wendan Ren et al.   Cell Reports

Human single-stranded DNA binding proteins are essential for maintaining genomic stability

(2013) Nicholas W Ashton et al.   BMC MOLECULAR BIOLOGY

A core hSSB1-INTS complex participates in the DNA damage response

(2013) F. Zhang et al.   JOURNAL OF CELL SCIENCE

Structural basis for the modular recognition of single-stranded RNA by PPR proteins

(2013) Ping Yin et al.   NATURE

Structural basis for RNA recognition by a dimeric PPR-protein complex

(2013) Jiyuan Ke et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-Stranded DNA-Binding Proteins: Multiple Domains for Multiple Functions

(2013) Thayne H. Dickey et al.   STRUCTURE

The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1

(2012) Soo-Hyun Yang et al.   EMBO JOURNAL

An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation

(2012) J. Chen et al.   RNA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Nucleic acid recognition by tandem helical repeats

(2011) Emily H Rubinson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

(2011) Derek J. Richard et al.   NUCLEIC ACIDS RESEARCH

Multi-crystal anomalous diffraction for low-resolution macromolecular phasing

(2010) Qun Liu et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Subset of Drosophila Integrator Proteins Is Essential for Efficient U7 snRNA and Spliceosomal snRNA 3'-End Formation

(2010) N. Ezzeddine et al.   MOLECULAR AND CELLULAR BIOLOGY

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex

(2010) Derek J. Richard et al.   NUCLEIC ACIDS RESEARCH

Integrator3, a Partner of Single-stranded DNA-binding Protein 1, Participates in the DNA Damage Response

(2009) Feng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response

(2009) Yongjiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

INTS3 controls the hSSB1-mediated DNA damage response

(2009) Jeffrey R. Skaar et al.   JOURNAL OF CELL BIOLOGY

SOSS Complexes Participate in the Maintenance of Genomic Stability

(2009) Jun Huang et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

In Situ Proteolysis to Generate Crystals for Structure Determination: An Update

(2009) Amy Wernimont et al.   PLoS One

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs

(2009) S. Kosugi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-damage repair; the good, the bad, and the ugly

(2008) Razqallah Hakem   EMBO JOURNAL

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

(2008) Derek J. Richard et al.   NATURE

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY