A Tbc1d1 Ser231Ala-knockin mutation partially impairs AICAR- but not exercise-induced muscle glucose uptake in mice

The Inactivation of RabGAP Function of AS160 Promotes Lysosomal Degradation of GLUT4 and Causes Postprandial Hyperglycemia and Hyperinsulinemia

(2016) Bingxian Xie et al.   DIABETES

Disruption of the AMPK–TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion

(2016) Liang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice

(2015) Stefan R. Hargett et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle

(2015) Jacqueline Stöckli et al.   DIABETES

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

(2014) Ida Moltke et al.   NATURE

Conventional Knockout ofTbc1d1in Mice Impairs Insulin- and AICAR-Stimulated Glucose Uptake in Skeletal Muscle

(2013) Janine Dokas et al.   ENDOCRINOLOGY

Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

(2012) Serge Ducommun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis

(2012) Melissa N. Lansey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

(2012) Ferenc Szekeres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

(2012) Hong Yu Wang et al.   BIOCHEMICAL JOURNAL

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

(2011) Shuai Chen et al.   Cell Metabolism

Insulin-stimulated GLUT4 Protein Translocation in Adipocytes Requires the Rab10 Guanine Nucleotide Exchange Factor Dennd4C

(2011) Hiroyuki Sano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

(2011) Shuai Chen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Kinetics of Contraction-Induced GLUT4 Translocation in Skeletal Muscle Fibers From Living Mice

(2010) H. P. M. M. Lauritzen et al.   DIABETES

TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

(2010) D. An et al.   DIABETES

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity

(2010) Gregory R. Steinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

(2009) Christian Pehmøller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AMPK and the biochemistry of exercise: implications for human health and disease

(2009) Erik A. Richter et al.   BIOCHEMICAL JOURNAL

AMPK: Lessons from transgenic and knockout animals

(2009) Benoit Viollet   Frontiers in Bioscience-Landmark

Insulin-stimulated Phosphorylation of the Rab GTPase-activating Protein TBC1D1 Regulates GLUT4 Translocation

(2009) Grantley R. Peck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia

(2009) S. Dash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

(2008) Kei Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

Gain-of-function R225Q Mutation in AMP-activated Protein Kinase γ3 Subunit Increases Mitochondrial Biogenesis in Glycolytic Skeletal Muscle

(2008) Pablo M. Garcia-Roves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

(2008) Alexandra Chadt et al.   NATURE GENETICS