Glucagon: acute actions on hepatic metabolism

Recent progress in the development of small-molecule glucagon receptor antagonists

(2015) Matthew F. Sammons et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Evaluation of Efficacy and Safety of the Glucagon Receptor Antagonist LY2409021 in Patients With Type 2 Diabetes: 12- and 24-Week Phase 2 Studies

(2015) Christof M. Kazda et al.   DIABETES CARE

Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes

(2015) R. P. Kelly et al.   DIABETES OBESITY & METABOLISM

Calcium-dependent regulation of glucose homeostasis in the liver

(2014) Paula J. Bartlett et al.   CELL CALCIUM

Glucagon Regulation of Oxidative Phosphorylation Requires an Increase in Matrix Adenine Nucleotide Content through Ca2+Activation of the Mitochondrial ATP-Mg/PiCarrier SCaMC-3

(2013) Ignacio Amigo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

(2012) Roger H. Unger et al.   JOURNAL OF CLINICAL INVESTIGATION

Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist

(2012) James Mu et al.   PLoS One

Hormonal Regulation of Hepatic Glucose Production in Health and Disease

(2011) Hua V. Lin et al.   Cell Metabolism

Glucagonoma and the glucagonoma syndrome - cumulative experience with an elusive endocrine tumour

(2011) Roy Eldor et al.   CLINICAL ENDOCRINOLOGY

Chronic treatment with a glucagon receptor antagonist lowers glucose and moderately raises circulating glucagon and glucagon-like peptide 1 without severe alpha cell hypertrophy in diet-induced obese mice

(2011) J. Mu et al.   DIABETOLOGIA

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL