Article
Infectious Diseases
Michela Galgano, Paolo Capozza, Francesco Pellegrini, Marco Cordisco, Alessio Sposato, Sabina Sblano, Michele Camero, Gianvito Lanave, Giuseppe Fracchiolla, Marialaura Corrente, Francesco Cirone, Adriana Trotta, Maria Tempesta, Domenico Buonavoglia, Annamaria Pratelli
Summary: The study found that essential oils such as lemon, pine, fennel, basil, melissa, thyme, and ginger have broad-spectrum antimicrobial activity. The activity of ginger oil against Staphylococcus aureus strains showed a dose-effect correlation, while fennel oil showed low activity. Pine, melissa, and basil oils showed bactericidal effects against S. aureus, and lemon oil had different effects on different strains. Thyme oil showed complete inhibition of growth for both E. coli and S. aureus.
Article
Biochemistry & Molecular Biology
Yeseul Kim, Sanghun Kim, Kiu-Hyung Cho, Jin-Hyung Lee, Jintae Lee
Summary: Bacterial biofilm formation can be effectively inhibited by cinnamaldehyde and its derivatives, especially 4-nitrocinnamaldehyde. These compounds exhibit strong antibiofilm activities against UPEC and S. aureus, making them promising candidates for the treatment of biofilm-associated diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Fabio Camacho-Alonso, Jesus Salinas, Mariano Sanchez-Siles, Jesus Pato-Mourelo, Brian Davis Cotrina-Veizaga, Nieves Ortega
Summary: The combination of PDT and chitosan shows a synergistic antimicrobial effect against bacteria related to peri-implantitis, with PDT + chitosan being the most effective treatment among the three bacteria studied. Further in vivo studies are needed to validate these findings in clinical settings.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Merilin Rosenberg, Meeri Visnapuu, Kristjan Saal, Dmytro Danilian, Rainer Parna, Angela Ivask, Vambola Kisand
Summary: In the context of healthcare-acquired infections and the spread of antibiotic resistance, additional passive measures are urgently needed to prevent pathogen carryover. Antimicrobial high-touch surfaces, such as photocatalytic nano-ZnO and nano-ZnO/Ag-based surfaces with significant reduction in bacterial viability, show potential for mitigating the spread of bacteria. It is important to critically evaluate and select appropriate efficacy assessment methods based on end-use conditions for these surfaces.
Article
Biochemistry & Molecular Biology
Huan Peng, Gang Zhou, Xi-Miao Yang, Guo-Jun Chen, Hai-Bin Chen, Zhen-Lin Liao, Qing-Ping Zhong, Li Wang, Xiang Fang, Jie Wang
Summary: Lactobacillus rhamnosus SCB0119 and its cell-free culture supernatant (CFS) could be used as a biocontrol agent against Escherichia coli and Staphylococcus aureus, with mechanisms involving induction of oxidative stress, disruption of cell wall and membrane structure, and alteration of key genes at the transcriptional level.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Multidisciplinary
Zhang Hui-lin, Zhao Yi-yang, Zhou Zi-chong, Ding Huan-zhong
Summary: In this study, the susceptibility breakpoints of cefquinome against E. coli and S. aureus in pigs were determined, with low resistance rates observed. Pharmacokinetic/pharmacodynamic cut-off values were established, providing guidance for effective treatment of infections caused by these bacteria strains. Adjustment of dosing regimen showed increased effectiveness for S. aureus infections, highlighting the importance of surveillance and dosage guidance for cefquinome in pigs.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2021)
Article
Chemistry, Applied
Lili Li, Ping Zhou, Yidi Wang, Ying Pan, Min Chen, Ye Tian, Hua Zhou, Baoru Yang, Hecheng Meng, Jie Zheng
Summary: Enzymatic acylation of anthocyanin with fatty acid improves its lipophilic solubility and this study demonstrates that the resulting acylated anthocyanin, C3G-LA, exhibits strong antibacterial activity against Staphylococcus aureus and moderate activity against Escherichia coli. The mechanism of action involves disruption of cell membrane integrity, intracellular ATP concentration, intracellular pH, and changes in cellular morphology.
Article
Chemistry, Applied
Yu-gang Shi, Run-run Zhang, Chen-min Zhu, Ming-feng Xu, Qing Gu, Rammile Ettelaie, Shan Lin, Yi-fan Wang, Xin-yi Leng
Summary: This study found that the length of alkyl gallates plays a crucial role in their antibacterial activity, with octyl gallate exhibiting excellent bactericidal activity through a multiple bactericidal mechanism and unique advantages in maintaining food freshness.
Article
Chemistry, Inorganic & Nuclear
Shafiyeh Abdollahzadeh, Mohammad Hossein Sayadi, Hossein Shekari
Summary: This research focuses on synthesizing a metal-organic framework nanocomposite supported by chitosan and graphene oxide to investigate its antibacterial properties and pollutant degradation ability. The synthesized MOF-CS/GO nanocomposite exhibits high antibacterial activity against Staphylococcus aureus and Escherichia coli, and also shows efficient degradation of methyl orange dye through photocatalysis. The results suggest that MOF-CS/GO is a promising and environmentally friendly nanocomposite in the fields of antibacterial and pollutant degradation.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
C. Guerra, A. Ringuede, M. I. Azocar, M. Walter, C. Galarce, F. Bedioui, M. Cassir, M. Sancy
Summary: AISI 430 stainless steel is an attractive material for use in the healthcare industry, but shows clear signs of corrosion after two weeks of exposure in a sterile medium.
Article
Food Science & Technology
Hong Yan, Yingying Lu, Xin Li, Yanglei Yi, Xin Wang, Yuanyuan Shan, Bianfang Liu, Yuan Zhou, Xin Lu
Summary: Bacteriocin BM1829 has antimicrobial activity against both Gram-positive and Gram-negative bacteria, and exhibits good stability against various environmental factors. It can disrupt membrane integrity, arrest the cell cycle, and reduce bacterial populations during food storage, suggesting its potential as a food preservative or antibacterial agent.
Article
Food Science & Technology
N. Aziman, M. Jawaid, N. A. Abdul Mutalib, N. L. Yusof, A. H. Nadrah, U. K. Nazatul, V. V. Tverezovskiy, O. A. Tverezovskaya, H. Fouad, R. M. Braganca, P. W. Baker, S. Selbie, A. Ali
Summary: This study demonstrated the effectiveness of films added with sage extracts in inhibiting bacterial growth and extending the storage time of refrigerated chicken meat, without compromising the quality of the product.
Article
Engineering, Environmental
Li-Ting Yen, Chih-Huang Weng, Nhu Anh Thi Than, Jing-Hua Tzeng, Astrid R. Jacobson, Kesinee Iamsaard, Van Dien Dang, Yao-Tung Lin
Summary: This study characterized the mode of inactivation of S. aureus and E. coli via biocalcium oxide (BCO) using various microscopy and spectroscopy techniques. The results demonstrated that BCO altered bacterial cell permeability, leading to sustained inactivation. BCO exhibited superior disinfection capacity compared to other shell-derived disinfectants, making it a cost-effective option for pathogen control.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Materials Science, Ceramics
Jose Domingo Trujillo-Casarreal, Jesus Morales-Jimenez, V Rodriguez-Gonzalez
Summary: Metallic nanoparticles (NPs) with size and morphology that enable a large surface-to-volume ratio exhibit antibacterial properties. The surface functionalization of copper sulfide NPs on mesoporous SiO2 spheres (PMSi) was successfully achieved. The antibacterial activity of PMSi loaded with sulfamethoxazole (SMX) against Escherichia coli and Staphylococcus aureus was studied. CuS and Cu functionalized on PMSi exhibited a good spectrum of antimicrobial activity against Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Biochemistry & Molecular Biology
Ahmed Emadelddin Mohamed, Amro Shetta, James Kegere, Wael Mamdouh
Summary: In this study, nanofibers embedded with Chicory root extract (CRE) in the Polyvinyl alcohol (PVA)/Chitosan (CS) nanocomposite were proposed as a safe and effective antibacterial solution. The optimum extraction solvent and drying method were determined, as well as the optimal electrospinner parameters for smooth nanofibers. The results showed that the PVA/CS/CRE-50 mg nanofibers exhibited potent antibacterial and antioxidant properties, surpassing the pure extract by 50 times and the PVA/CS nanofibers by 23 times in terms of antibacterial and antioxidant activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biology
Kristinn Gudnason, Sven Sigurdsson, Bergthora S. Snorradottir, Mar Masson, Fjola Jonsdottir
MATHEMATICAL BIOSCIENCES
(2018)
Article
Biochemistry & Molecular Biology
Priyanka Sahariah, Mar Masson, Rikke Louise Meyer
Article
Biochemistry & Molecular Biology
Priyanka Sahariah, Dorota Cibor, Dorota Zielinska, Martha A. Hjalmarsdottir, Dawid Stawski, Mar Masson
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Chemistry, Medicinal
Amogh Kulkarni, Isha Soni, Dhanashree S. Kelkar, Allimuthu T. Dharmaraja, Rathinam K. Sankar, Gaurav Beniwal, Abinaya Rajendran, Sharvari Tamhankar, Sidharth Chopra, Siddhesh S. Kamat, Harinath Chakrapani
JOURNAL OF MEDICINAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Abhilash D. Pandya, Anders Overbye, Priyanka Sahariah, Vivek S. Gaware, Hakon Hogset, Mar Masson, Anders Hogset, Gunhild M. Maelandsmo, Tore Skotland, Kirsten Sandvig, Tore-Geir Iversen
Article
Ophthalmology
Helena P. Filipe, Dimitriya Bozukova, Andreia Pimenta, Ana Paula Vieira, Andreia Sofia Oliveira, Raquel Galante, Ana Topete, Mar Masson, Patricia Alves, Patricia Coimbra, M. Helena Gil, A. Jorge Guiomar, Jose Mata, Rogerio Colaco, Benilde Saramago, Liliana Werner, Nick Mamalis, Ana Paula Serro
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2019)
Article
Biochemistry & Molecular Biology
Sankar Rathinam, Sigriour Olafsdottir, Sigriour Jonsdottir, Martha A. Hjalmarsdottir, Mar Masson
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Chemistry, Applied
Priyanka Sahariah, Ana Paula Vieira, Antonio Jorge Guiomar, Patricia Alves, Mar Masson
REACTIVE & FUNCTIONAL POLYMERS
(2020)
Article
Chemistry, Applied
Mousumi Sukul, Priyanka Sahariah, Helene L. Lauzon, Joao Borges, Mar Masson, Joao F. Mano, Havard J. Haugen, Janne E. Reseland
Summary: The DDA and Mw of chitosan sponges affect adhesion, growth, and differentiation of primary human osteoblasts. Higher DDA promotes the secretion of bone growth factors, while lower DDA promotes the secretion of other proteins. The variations in cellular responses to different chitosan sponges suggest potential for individual tailoring of desired responses in guided bone regeneration.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Sankar Rathinam, Martha A. Hjalmarsdottir, Mikkel B. Thygesen, Mar Masson
Summary: This study presents a novel synthesis method for a new type of polysaccharides derived from chitosan, by quantitatively replacing the 2-amino group on the pyranose ring with an aromatic 1,2,3-triazole moiety and converting it to triazoles through a copper-catalysed Huisgen cycloaddition reaction. Triazole derivatives with specific substituents showed solubility in water under neutral or basic conditions and exhibited high activity against Staphylococcus aureus and Escherichia coli.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Medicinal
Guglielmo Vesco, Martino Brambati, Luca Scapinello, Andrea Penoni, Massimo Mella, Mar Masson, Vivek Gaware, Angelo Maspero, Luca Nardo
Summary: This study synthesized two asymmetric curcumin analogs with improved fluorescent stability through introducing molecular structural asymmetry. The electronic structure and proton transfer propensity of the asymmetric compounds were investigated through electronic structure calculations and nuclear magnetic resonance experiments. Moreover, their singlet oxygen-generation efficiency was compared to that of curcumin.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)