Article
Polymer Science
Erik Francisco Najera-Martinez, Elda A. Flores-Contreras, Rafael G. Araujo, Maricarmen Iniguez-Moreno, Juan Eduardo Sosa-Hernandez, Hafiz M. N. Iqbal, Lorenzo M. Pastrana, Elda M. Melchor-Martinez, Roberto Parra-Saldivar
Summary: The encapsulation of gallic acid using pectin and alginate through spray drying has been shown to enhance its stability and has potential applications in the food, pharmaceutical, and cosmetic industries.
Article
Chemistry, Applied
Guido Rolandelli, Silvio David Rodriguez, Maria del Pilar Buera
Summary: The effects of pectin (P), guar gum (GG), and gallic acid (GA) on the pasting properties and retrogradation kinetics of sweet potato starch (SPS) during storage were investigated. Results showed that the addition of GG increased viscosity, while P and GA had the opposite effect. GA effectively delayed retrogradation, resulting in lower turbidity and retrogradation degree. GG promoted retrogradation by breaking the structure of swollen starch granules.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Analytical
Huda M. Younis, A. O. Youssef, Said M. El-Sheikh, Sheta M. Sheta, Mohamed S. Attia
Summary: Fe-Gallic acid metal organic framework (MOF) was synthesized and characterized for use as a sensor to detect the antiviral drug Molnupiravir. The Fe-Gallic acid MOF sensor is highly sensitive and cost-effective, and does not require special equipment. It has potential applications in various settings, including clinical laboratories and point-of-care.
MICROCHEMICAL JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Dorota Wianowska, Malgorzata Olszowy-Tomczyk
Summary: Nature provides valuable anti-oxidants, such as gallic acid, which has been used for its healing properties since ancient times. Due to its beneficial properties, gallic acid has become essential in various industries, serving as a protection against UV radiation, an astringent in cosmetics, and a preservative in food products. This review updates the knowledge about gallic acid's biological activities and methods used for its isolation and determination.
Article
Materials Science, Multidisciplinary
Soo-Ah Jin, Tero Kamarainen, Patrick Rinke, Orlando J. Rojas, Milica Todorovic
Summary: In this study, machine learning was used to design particles of oxidized tannic acid (OTA) and correlate their size and shape with colloidal suspension conditions. The results showed that a small number of experiments were sufficient to build predictive models of OTA morphology, and multiple property landscapes were generated to infer solutions that met multiple design objectives.
Article
Polymer Science
Asmaa Sayed, Fatma Hany, Manar El-Sayed Abdel-Raouf, Ghada A. Mahmoud
Summary: In this study, bio-based hydrogels composed of pectin and polyacrylic acid were prepared by gamma radiation and reinforced with different ratios of gallic acid. The results showed that the incorporation of gallic acid enhanced the swelling performance of the hydrogel, reaching an optimum value before decreasing. The hydrogels displayed excellent antibacterial activity and efficient removal of lead ions.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Shohreh Jafarinejad, William H. C. Martin, Bayan Abu Ras, Mohammad Isreb, Badie Jacob, Abid Aziz, Zahra Adoul, Ruby Lagnado, Richard D. Bowen, Mojgan Najafzadeh
Summary: The compound TMBS shows a stronger anticancer effect compared to GA, suppressing the growth and proliferation of lung cancer cells. Furthermore, TMBS does not show cytotoxicity to healthy cells, suggesting its potential for cancer therapeutics.
Review
Materials Science, Paper & Wood
Hendryk Wuerfel, Katj A. Geitel, Haisong Qi, Thomas Heinze
Summary: Pectin, a sustainable biopolymer, has attracted increasing attention in various industries due to its potential applications beyond being a food additive. Recent research on chemical modifications of pectin has provided insights for designing novel biopolymer-based materials with tailored properties.
Article
Environmental Sciences
Yu Huang, Jiewen Yang
Summary: The presence of gallic acid (GA) was found to significantly promote the transformation of SMX by birnessite, especially at pH 6.0 compared to pH 4.0. The promotive effect was attributed to the addition reactions between SMX and GA quinones, as well as condensation reactions between -COOH of quinones and -NH2 of SMX or its transformation products.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Environmental
Liang Cai, Yuze Zhang, Xiaowu Peng, Fan Guo, Lianmin Ji, Lijuan Li
Summary: In this study, GA-LDH material was synthesized for borate acid adsorption and achieved a high adsorption capacity under optimized conditions, showing better adsorption performance compared to conventional materials. The research on adsorption mechanism and thermodynamics revealed the complex reaction process of boron adsorption by GA-LDH.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Nutrition & Dietetics
Lisard Iglesias-Carres, Lauren A. Essenmacher, Kathryn C. Racine, Andrew P. Neilson
Summary: The study aimed to develop a method to inhibit choline metabolism into TMA by gut microbiota using phenolic compounds. Results showed that DMB, gallic acid, and chlorogenic acid were effective TMA inhibitors that could significantly reduce TMA production, potentially through altering TMA-lyase activity or expression.
Article
Biochemistry & Molecular Biology
Damian Tarasek, Hubert Wojtasek, Khedidja Benarous, Mohamed Yousfi
Summary: Gallic acid and hispidin were previously described as inhibitors of horseradish peroxidase, but additional experiments showed that both compounds are rapidly oxidized by the enzyme. Although it was interpreted as enzyme inhibition, the activity of horseradish peroxidase is not affected by these compounds.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Polymer Science
Maria Marzano, Nicola Borbone, Felice Amato, Giorgia Oliviero, Pierpaolo Fucile, Teresa Russo, Filomena Sannino
Summary: Three-dimensional chitosan-gallic acid complexes were prepared by adsorbing gallic acid on three-dimensional chitosan structures. The complexes exhibited high antioxidant activity and antimicrobial capacity, making them suitable for nutraceutical, cosmeceutical, and pharmaceutical applications.
Article
Chemistry, Applied
Ying Li, Lezhen Dong, Yahui Liu, Qin Chen, Zufang Wu, Lingyi Liu, Mohamed A. Farag, Lianliang Liu
Summary: The effects of covalent binding of protocatechuic acid (PA) and gallic acid (GA) to lactoferrin (LF) on the structure, functional, and antioxidant properties of the protein conjugate were investigated. The LF-PA/GA conjugates showed altered hydrodynamic diameter and zeta-potential, but their antioxidant activities remained unchanged.
Article
Biochemistry & Molecular Biology
Ang-Tse Lee, Mon-Yuan Yang, Yi-Ju Lee, Tzu-Wei Yang, Chi-Chih Wang, Chau-Jong Wang
Summary: This study found that gallic acid (GA) can improve hepatic lipid metabolism and diabetic fatty liver by downregulating the expression of miR-34a-5p. GA improves the condition of high-fat diet-induced steatotic mice by increasing antioxidant enzyme activity and inhibiting lipid accumulation. In addition, silencing miR-34a-5p can also reduce lipid accumulation in hepatocytes.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)