Starvation Responses Throughout the Caenorhabditiselegans Life Cycle

The Rheb-TORC1 signaling axis functions as a developmental checkpoint

(2020) Tam Duong et al.   DEVELOPMENT

Insights Into the Hypometabolic Stage Caused by Prolonged Starvation in L4-Adult Caenorhabditis elegans Hermaphrodites

(2020) E. Carranza-García et al.   Frontiers in Cell and Developmental Biology

HLH-30/TFEB Is a Master Regulator of Reproductive Quiescence

(2020) Birgit Gerisch et al.   DEVELOPMENTAL CELL

Organismal Protein Homeostasis Mechanisms

(2020) Thorsten Hoppe et al.   GENETICS

Neurogenetics of nictation, a dispersal strategy in nematodes

(2020) Heeseung Yang et al.   JOURNAL OF NEUROGENETICS

A Natural Mutational Event Uncovers a Life History Trade-Off via Hormonal Pleiotropy

(2020) Bénédicte Billard et al.   CURRENT BIOLOGY

Behavioral States

(2020) Steven W. Flavell et al.   GENETICS

Feeding state sculpts a circuit for sensory valence in Caenorhabditis elegans

(2019) Sophie Rengarajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans

(2019) Elif Sarinay Cenik et al.   DEVELOPMENTAL CELL

Cell Non-autonomous Function of daf-18/PTEN in the Somatic Gonad Coordinates Somatic Gonad and Germline Development in C. elegans Dauer Larvae

(2019) Claudia C. Tenen et al.   CURRENT BIOLOGY

Plasticity of the Electrical Connectome of C. elegans

(2019) Abhishek Bhattacharya et al.   CELL

Short-term starvation stress at young adult stages enhances meiotic activity of germ cells to maintain spermatogenesis in aged male Caenorhabditis elegans

(2019) Wan-Yi Chou et al.   AGING CELL

Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans

(2019) Orkan Ilbay et al.   CURRENT BIOLOGY

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

(2019) John T. Murphy et al.   PLOS BIOLOGY

Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress

(2019) James M. Jordan et al.   CURRENT BIOLOGY

Apoptosis contributes to protect germ cells from the oogenic germline starvation response but is not essential for the gonad shrinking or recovery observed during adult reproductive diapause in C. elegans

(2019) E. Carranza-García et al.   PLoS One

Coelomocytes Regulate Starvation-Induced Fat Catabolism and Lifespan Extension through the Lipase LIPL-5 in Caenorhabditis elegans

(2019) Alexia Buis et al.   Cell Reports

AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway

(2019) Pratik Kadekar et al.   PLOS BIOLOGY

TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging

(2019) T. Keith Blackwell et al.   GENETICS

A hormone receptor pathway cell-autonomously delays neuron morphological aging by suppressing endocytosis

(2019) Claire E. Richardson et al.   PLOS BIOLOGY

Prolonged quiescence delays somatic stem cell‐like divisions in Caenorhabditis elegans and is controlled by insulin signaling

(2019) María Olmedo et al.   AGING CELL

Hedgehog-related genes regulate reactivation of quiescent neural progenitors in Caenorhabditis elegans

(2019) Masahiko Kume et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipase-like 5 enzyme controls mitochondrial activity in response to starvation in Caenorhabditis elegans

(2019) Felipe Macedo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biology of the Caenorhabditis elegans Germline Stem Cell System

(2019) E. Jane Albert Hubbard et al.   GENETICS

Requirement for translocon-associated protein (TRAP) α in insulin biogenesis

(2019) Xin Li et al.   Science Advances

NHR-49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting

(2018) Grace Y. S. Goh et al.   AGING CELL

Food-Dependent Plasticity inCaenorhabditis elegansStress-Induced Sleep Is Mediated by TOR-FOXA and TGF-β Signaling

(2018) Desiree L. Goetting et al.   GENETICS

PHA-4/FoxA senses nucleolar stress to regulate lipid accumulation in Caenorhabditis elegans

(2018) Jieyu Wu et al.   Nature Communications

Visible light reduces C. elegans longevity

(2018) C. Daniel De Magalhaes Filho et al.   Nature Communications

Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves

(2018) Celina Galles et al.   Scientific Reports

Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause

(2018) Bree Heestand et al.   Cell Reports

Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans

(2018) Susanne Skora et al.   Cell Reports

Early experiences mediate distinct adult gene expression and reproductive programs in Caenorhabditis elegans

(2018) Maria C. Ow et al.   PLoS Genetics

Food-Dependent Plasticity inCaenorhabditis elegansStress-Induced Sleep Is Mediated by TOR-FOXA and TGF-β Signaling

(2018) Desiree L. Goetting et al.   GENETICS

Non-selective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans

(2018) Jonathan D Hibshman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity inCaenorhabditis elegans

(2018) Amy K. Webster et al.   GENETICS

A functional study of all 40 C. elegans insulin-like peptides

(2018) Shanqing Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Past experience shapes sexually dimorphic neuronal wiring through monoaminergic signalling

(2018) Emily A. Bayer et al.   NATURE

Physiological Starvation PromotesCaenorhabditis elegansVulval Induction

(2018) Stéphanie Grimbert et al.   G3-Genes Genomes Genetics

Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans

(2018) Rebecca E. W. Kaplan et al.   BMC BIOLOGY

Sleep Counteracts Aging Phenotypes to Survive Starvation-Induced Developmental Arrest in C. elegans

(2018) Yin Wu et al.   CURRENT BIOLOGY

C. elegans PTEN and AMPK block neuroblast divisions by inhibiting a BMP-insulin-PP2A-MAPK pathway

(2018) Shanqing Zheng et al.   DEVELOPMENT

A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila

(2018) Naoki Okamoto et al.   DEVELOPMENTAL CELL

Pervasive Positive and Negative Feedback Regulation of Insulin-Like Signaling in Caenorhabditis elegans

(2018) Rebecca E. W. Kaplan et al.   GENETICS

Intergenerational and transgenerational epigenetic inheritance in animals

(2018) Marcos Francisco Perez et al.   NATURE CELL BIOLOGY

Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation inCaenorhabditis elegans

(2017) Warakorn Kulalert et al.   GENETICS

Endogenous RNAi Pathways Are Required in Neurons for Dauer Formation in Caenorhabditis elegans

(2017) Pallavi S. Bharadwaj et al.   GENETICS

The Natural Biotic Environment ofCaenorhabditis elegans

(2017) Hinrich Schulenburg et al.   GENETICS

Maternal age generates phenotypic variation in Caenorhabditis elegans

(2017) Marcos Francisco Perez et al.   NATURE

Phosphorylated glycosphingolipids essential for cholesterol mobilization in Caenorhabditis elegans

(2017) Sebastian Boland et al.   Nature Chemical Biology

AMPK blocks starvation-inducible transgenerational defects inCaenorhabditis elegans

(2017) Emilie Demoinet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Serotonin Transporter and Early Life Stress: Translational Perspectives

(2017) Danielle J. Houwing et al.   Frontiers in Cellular Neuroscience

Environmental stresses induce transgenerationally inheritable survival advantages via germline-to-soma communication in Caenorhabditis elegans

(2017) Saya Kishimoto et al.   Nature Communications

Genome-wide RNAi Screen for Fat Regulatory Genes in C. elegans Identifies a Proteostasis-AMPK Axis Critical for Starvation Survival

(2017) Christopher M. Webster et al.   Cell Reports

daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival

(2017) Jonathan D Hibshman et al.   eLife

Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation inCaenorhabditis elegans

(2017) Warakorn Kulalert et al.   GENETICS

Endogenous RNAi Pathways Are Required in Neurons for Dauer Formation in Caenorhabditis elegans

(2017) Pallavi S. Bharadwaj et al.   GENETICS

The Natural Biotic Environment ofCaenorhabditis elegans

(2017) Hinrich Schulenburg et al.   GENETICS

Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans

(2017) Eva Bang Harvald et al.   Cell Systems

Antioxidant response is a protective mechanism against nutrient deprivation in C. elegans

(2017) Jun Tao et al.   Scientific Reports

Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans

(2016) Antoine E. Roux et al.   Cell Metabolism

A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2 /insulin signaling and by the TGF-β/Sma/Mab pathway

(2016) Barbara Goszczynski et al.   DEVELOPMENTAL BIOLOGY

Cell cycle features of C. elegans germline stem/progenitor cells vary temporally and spatially

(2016) Debasmita Roy et al.   DEVELOPMENTAL BIOLOGY

Linking Gene Expression in the Intestine to Production of Gametes Through the Phosphate Transporter PITR-1 in Caenorhabditis elegans

(2016) Zita Balklava et al.   GENETICS

BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans

(2016) Moonjung Hyun et al.   GENETICS

Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans

(2016) Mingxue Cui et al.   GENETICS

Sex-specific pruning of neuronal synapses in Caenorhabditis elegans

(2016) Meital Oren-Suissa et al.   NATURE

A hybrid polyketide–nonribosomal peptide in nematodes that promotes larval survival

(2016) Qingyao Shou et al.   Nature Chemical Biology

C. elegans Body Cavity Neurons Are Homeostatic Sensors that Integrate Fluctuations in Oxygen Availability and Internal Nutrient Reserves

(2016) Emily Witham et al.   Cell Reports

A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans

(2016) Peter Erdelyi et al.   G3-Genes Genomes Genetics

Fluorescent Beads Are a Versatile Tool for Staging Caenorhabditis elegans in Different Life Histories

(2016) Liberta Nika et al.   G3-Genes Genomes Genetics

Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans

(2016) Edward E. Large et al.   PLoS Genetics

Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance

(2016) Jonathan D. Hibshman et al.   PLoS Genetics

Developmental programming modulates olfactory behavior in C. elegans via endogenous RNAi pathways

(2016) Jennie R Sims et al.   eLife

AMPK acts as a molecular trigger to coordinate glutamatergic signals and adaptive behaviours during acute starvation

(2016) Moloud Ahmadi et al.   eLife

Linking Gene Expression in the Intestine to Production of Gametes Through the Phosphate Transporter PITR-1 in Caenorhabditis elegans

(2016) Zita Balklava et al.   GENETICS

BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans

(2016) Moonjung Hyun et al.   GENETICS

Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans

(2016) Mingxue Cui et al.   GENETICS

Octopamine connects nutrient cues to lipid metabolism upon nutrient deprivation

(2016) J. Tao et al.   Science Advances

NAD+ Is a Food Component That Promotes Exit from Dauer Diapause in Caenorhabditis elegans

(2016) Mykola Mylenko et al.   PLoS One

Tissue-specific autophagy responses to aging and stress in C. elegans

(2015) Hannah C. Chapin et al.   Aging-US

Autophagy-mediated longevity is modulated by lipoprotein biogenesis

(2015) Nicole E. Seah et al.   Autophagy

Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster

(2015) Naoki Yamanaka et al.   CELL

The C. elegans Hypodermis Couples Progenitor Cell Quiescence to the Dietary State

(2015) Masamitsu Fukuyama et al.   CURRENT BIOLOGY

Zygotic Genome Activation Triggers Chromosome Damage and Checkpoint Signaling in C. elegans Primordial Germ Cells

(2015) Melina Butuči et al.   DEVELOPMENTAL CELL

A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans

(2015) Marina Kniazeva et al.   DEVELOPMENTAL CELL

Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans

(2015) M. A. Jobson et al.   GENETICS

Longevity Genes Revealed by Integrative Analysis of Isoform-Specificdaf-16/FoxOMutants ofCaenorhabditis elegans

(2015) Albert Tzong-Yang Chen et al.   GENETICS

Global Proteomics Analysis of the Response to Starvation inC. elegans

(2015) Mark Larance et al.   MOLECULAR & CELLULAR PROTEOMICS

Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies

(2015) G. Zadra et al.   MOLECULAR CANCER RESEARCH

miR-58 family and TGF-β pathways regulate each other inCaenorhabditis elegans

(2015) María Pilar de Lucas et al.   NUCLEIC ACIDS RESEARCH

Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans

(2015) Sider Penkov et al.   Nature Communications

Starvation-induced collective behavior in C. elegans

(2015) Alexander B. Artyukhin et al.   Scientific Reports

New genetic regulators question relevance of abundant yolk protein production in C. elegans

(2015) Liesbeth Van Rompay et al.   Scientific Reports

Co-chaperone p23 Regulates C. elegans Lifespan in Response to Temperature

(2015) Makoto Horikawa et al.   PLoS Genetics

dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest

(2015) Rebecca E. W. Kaplan et al.   PLoS Genetics

Correction: Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling

(2015) Scott J Neal et al.   eLife

C. elegans outside the Petri dish

(2015) Lise Frézal et al.   eLife

Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch

(2015) Hannah S Seidel et al.   eLife

Longevity Genes Revealed by Integrative Analysis of Isoform-Specificdaf-16/FoxOMutants ofCaenorhabditis elegans

(2015) Albert Tzong-Yang Chen et al.   GENETICS

Early life stress and hippocampal neurogenesis in the neonate: sexual dimorphism, long term consequences and possible mediators

(2015) Naima Lajud et al.   Frontiers in Molecular Neuroscience

High-Throughput Profiling of Caenorhabditis elegans Starvation-Responsive microRNAs

(2015) Laura Garcia-Segura et al.   PLoS One

Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans

(2014) Oded Rechavi et al.   CELL

Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan

(2014) Parag Mahanti et al.   Cell Metabolism

Cellular Stress Induces a Protective Sleep-like State in C. elegans

(2014) Andrew J. Hill et al.   CURRENT BIOLOGY

A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication

(2014) W. L. Hung et al.   DEVELOPMENT

Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest

(2014) Yutao Chen et al.   DEVELOPMENTAL BIOLOGY

DRE-1/FBXO11-Dependent Degradation of BLMP-1/BLIMP-1 Governs C. elegans Developmental Timing and Maturation

(2014) Moritz Horn et al.   DEVELOPMENTAL CELL

Doxycyclin ameliorates a starvation-induced germline tumor in C. elegans daf-18/PTEN mutant background

(2014) Tim Wolf et al.   EXPERIMENTAL GERONTOLOGY

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

(2014) Randall M. Chin et al.   NATURE

Bacterial Fatty Acids Enhance Recovery from the Dauer Larva in Caenorhabditis elegans

(2014) Tiffany K. Kaul et al.   PLoS One

Humidity sensation requires both mechanosensory and thermosensory pathways in Caenorhabditis elegans

(2014) J. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo

(2014) N. S. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation

(2014) Shanshan Pang et al.   Nature Communications

Pol II Docking and Pausing at Growth and Stress Genes in C. elegans

(2014) Colin S. Maxwell et al.   Cell Reports

Reduced Insulin/IGF-1 Signaling Restores Germ Cell Immortality to Caenorhabditis elegans Piwi Mutants

(2014) Matt Simon et al.   Cell Reports

Identification of Late Larval Stage Developmental Checkpoints in Caenorhabditis elegans Regulated by Insulin/IGF and Steroid Hormone Signaling Pathways

(2014) Adam J. Schindler et al.   PLoS Genetics

An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology

(2014) Diana Andrea Fernandes de Abreu et al.   PLoS Genetics

Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions

(2014) Katherine A. Cunningham et al.   PLoS Genetics

The conserved Mediator subunit MDT-15 is required for oxidative stress responses inCaenorhabditis elegans

(2013) Grace Y. S. Goh et al.   AGING CELL

PQM-1 Complements DAF-16 as a Key Transcriptional Regulator of DAF-2-Mediated Development and Longevity

(2013) Ronald G. Tepper et al.   CELL

The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation

(2013) Gabriel Leprivier et al.   CELL

The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans

(2013) Daniel B. Magner et al.   Cell Metabolism

Direct and Indirect Gene Regulation by a Life-Extending FOXO Protein in C. elegans: Roles for GATA Factors and Lipid Gene Regulators

(2013) Peichuan Zhang et al.   Cell Metabolism

The Unfolded Protein Response in a Pair of Sensory Neurons Promotes Entry of C. elegans into Dauer Diapause

(2013) Warakorn Kulalert et al.   CURRENT BIOLOGY

Dauer-Specific Dendrite Arborization in C. elegans Is Regulated by KPC-1/Furin

(2013) Nathan E. Schroeder et al.   CURRENT BIOLOGY

The Tumor Suppressor Rb Critically Regulates Starvation-Induced Stress Response in C. elegans

(2013) Mingxue Cui et al.   CURRENT BIOLOGY

DAF-2 and ERK Couple Nutrient Availability to Meiotic Progression during Caenorhabditis elegans Oogenesis

(2013) Andrew L. Lopez et al.   DEVELOPMENTAL CELL

 -6 Polyunsaturated fatty acids extend life span through the activation of autophagy

(2013) E. J. O'Rourke et al.   GENES & DEVELOPMENT

TheC. elegansTIA-1/TIAR homolog TIAR-1 is required to induce germ cell apoptosis

(2013) Silva-García Carlos Giovanni et al.   GENESIS

To Grow or Not to Grow: Nutritional Control of Development During Caenorhabditis elegans L1 Arrest

(2013) L. R. Baugh   GENETICS

Complex expression dynamics and robustness in C. elegans insulin networks

(2013) A. D. Ritter et al.   GENOME RESEARCH

Succinylated Octopamine Ascarosides and a New Pathway of Biogenic Amine Metabolism inCaenorhabditis elegans

(2013) Alexander B. Artyukhin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The microRNA miR-235 couples blast-cell quiescence to the nutritional state

(2013) Hidefumi Kasuga et al.   NATURE

TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

(2013) Carmine Settembre et al.   NATURE CELL BIOLOGY

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

(2013) Eyleen J. O’Rourke et al.   NATURE CELL BIOLOGY

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

(2013) Christian G. Riedel et al.   NATURE CELL BIOLOGY

WormSizer: High-throughput Analysis of Nematode Size and Shape

(2013) Brad T. Moore et al.   PLoS One

Insulin/IGF-1 Signaling, including Class II/III PI3Ks, β-Arrestin and SGK-1, Is Required in C. elegans to Maintain Pharyngeal Muscle Performance during Starvation

(2013) Donard S. Dwyer et al.   PLoS One

Functional Loss of Two Ceramide Synthases Elicits Autophagy-Dependent Lifespan Extension in C. elegans

(2013) Mai-Britt Mosbech et al.   PLoS One

Control of cell-fate plasticity and maintenance of multipotency by DAF-16/FoxO in quiescent Caenorhabditis elegans

(2013) X. Karp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans

(2013) S. E. Hall et al.   RNA

Density dependence in Caenorhabditis larval starvation

(2013) Alexander B. Artyukhin et al.   Scientific Reports

Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition

(2013) Michael Stadler et al.   PLoS Genetics

A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans

(2013) Huanhu Zhu et al.   eLife

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

(2013) William S Kruesi et al.   eLife

Physiological function, expression pattern, and transcriptional regulation of a Caenorhabditis elegans insulin-like peptide, INS-18

(2012) Yohei Matsunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

(2012) János Barna et al.   BMC DEVELOPMENTAL BIOLOGY

HSF-1 Regulators DDL-1/2 Link Insulin-like Signaling to Heat-Shock Responses and Modulation of Longevity

(2012) Wei-Chung Chiang et al.   CELL

Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response

(2012) Jennifer Paek et al.   Cell Metabolism

Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans

(2012) X. Karp et al.   DEVELOPMENT

S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells

(2012) D. Z. Korta et al.   DEVELOPMENT

Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans

(2012) C. S. Maxwell et al.   GENOME RESEARCH

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality

(2012) Bethany A. Buckley et al.   NATURE

Caenorhabditis elegans Battling Starvation Stress: Low Levels of Ethanol Prolong Lifespan in L1 Larvae

(2012) Paola V. Castro et al.   PLoS One

Metabolic Rate Regulates L1 Longevity in C. elegans

(2012) Inhwan Lee et al.   PLoS One

ASM-3 Acid Sphingomyelinase Functions as a Positive Regulator of the DAF-2/AGE-1 Signaling Pathway and Serves as a Novel Anti-Aging Target

(2012) Yongsoon Kim et al.   PLoS One

Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans

(2012) D. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Connectome of a Decision-Making Neural Network

(2012) T. A. Jarrell et al.   SCIENCE

A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity

(2012) Joshua Wollam et al.   PLOS BIOLOGY

Hormonal Signal Amplification Mediates Environmental Conditions during Development and Controls an Irreversible Commitment to Adulthood

(2012) Oren N. Schaedel et al.   PLOS BIOLOGY

C. elegansAMPKs promote survival and arrest germline development during nutrient stress

(2012) Masamitsu Fukuyama et al.   Biology Open

pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans

(2011) José M. Monje et al.   AGING CELL

Insulin/IGF-1 Receptor Signaling Enhances Biosynthetic Activity and Fat Mobilization in the Initial Phase of Starvation in Adult Male C. elegans

(2011) Kien Thiam Tan et al.   Cell Metabolism

Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation

(2011) Cihan Erkut et al.   CURRENT BIOLOGY

Specific insulin-like peptides encode sensory information to regulate distinct developmental processes

(2011) A. Cornils et al.   DEVELOPMENT

Reconsidering Movement of Eukaryotic mRNAs between Polysomes and P Bodies

(2011) Joshua A. Arribere et al.   MOLECULAR CELL

Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes

(2011) Patrick T. McGrath et al.   NATURE

Sensitive and Precise Quantification of Insulin-Like mRNA Expression in Caenorhabditis elegans

(2011) L. Ryan Baugh et al.   PLoS One

All Eggs Are Not Equal: The Maternal Environment Affects Progeny Reproduction and Developmental Fate in Caenorhabditis elegans

(2011) Simon C. Harvey et al.   PLoS One

The Oogenic Germline Starvation Response in C. elegans

(2011) Hannah S. Seidel et al.   PLoS One

microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause

(2011) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and Immunity

(2011) Claire E. Richardson et al.   PLoS Genetics

PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism

(2011) Sri Devi Narasimhan et al.   PLoS Genetics

Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism

(2011) Peter Meister et al.   GENOME BIOLOGY

Maradolipids: Diacyltrehalose Glycolipids Specific to Dauer Larva in Caenorhabditis elegans

(2010) Sider Penkov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

EAK-7 Controls Development and Life Span by Regulating Nuclear DAF-16/FoxO Activity

(2010) Hena Alam et al.   Cell Metabolism

A Cellular Memory of Developmental History Generates Phenotypic Diversity in C. elegans

(2010) Sarah E. Hall et al.   CURRENT BIOLOGY

Insulin signaling promotes germline proliferation in C. elegans

(2010) D. Michaelson et al.   DEVELOPMENT

The C. elegans developmental timing protein LIN-42 regulates diapause in response to environmental cues

(2010) J. M. Tennessen et al.   DEVELOPMENT

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan

(2010) Kathleen J. Dumas et al.   DEVELOPMENTAL BIOLOGY

The Developmental Timing Regulator hbl-1 Modulates the Dauer Formation Decision in Caenorhabditis elegans

(2010) X. Karp et al.   GENETICS

Reversal of Salt Preference Is Directed by the Insulin/PI3K and Gq/PKC Signaling in Caenorhabditis elegans

(2010) T. Adachi et al.   GENETICS

Insulin Signaling Plays a Dual Role in Caenorhabditis elegans Memory Acquisition and Memory Retrieval

(2010) C. H. A. Lin et al.   JOURNAL OF NEUROSCIENCE

TBC-2 Is Required for Embryonic Yolk Protein Storage and Larval Survival during L1 Diapause in Caenorhabditis elegans

(2010) Laëtitia Chotard et al.   PLoS One

Insulin Signaling and Dietary Restriction Differentially Influence the Decline of Learning and Memory with Age

(2010) Amanda L. Kauffman et al.   PLOS BIOLOGY

Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response

(2010) Mei Zhong et al.   PLoS Genetics

A PP2A Regulatory Subunit Regulates C. elegans Insulin/IGF-1 Signaling by Modulating AKT-1 Phosphorylation

(2009) Srivatsan Padmanabhan et al.   CELL

A C. elegans LSD1 Demethylase Contributes to Germline Immortality by Reprogramming Epigenetic Memory

(2009) David J. Katz et al.   CELL

IRE-1 and HSP-4 Contribute to Energy Homeostasis via Fasting-Induced Lipases in C. elegans

(2009) Hyunsun Jo et al.   Cell Metabolism

Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans

(2009) J. Thomas Hannich et al.   DEVELOPMENTAL CELL

Starvation Protects Germline Stem Cells and Extends Reproductive Longevity in C. elegans

(2009) G. Angelo et al.   SCIENCE

RNA Pol II Accumulates at Promoters of Growth Genes During Developmental Arrest

(2009) L. Ryan Baugh et al.   SCIENCE

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans

(2008) Sunhee Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

C. elegans Anaplastic Lymphoma Kinase Ortholog SCD-2 Controls Dauer Formation by Modulating TGF-β Signaling

(2008) David J. Reiner et al.   CURRENT BIOLOGY

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans

(2008) D. S. Patel et al.   DEVELOPMENT

Plasticity and Errors of a Robust Developmental System in Different Environments

(2008) Christian Braendle et al.   DEVELOPMENTAL CELL

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT

A branched-chain fatty acid is involved in post-embryonic growth control in parallel to the insulin receptor pathway and its biosynthesis is feedback-regulated in C. elegans

(2008) M. Kniazeva et al.   GENES & DEVELOPMENT

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans

(2008) A. J. Bretscher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TRPV Channel Modulates C. elegans Neurosecretion, Larval Starvation Survival, and Adult Lifespan

(2008) Brian H. Lee et al.   PLoS Genetics