A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity

(2011) Joshua Wollam et al.   AGING CELL

Sterol Regulation of Metabolism, Homeostasis, and Development

(2011) Joshua Wollam et al.   Annual Review of Biochemistry

N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans

(2011) Mark Lucanic et al.   NATURE

Fatty Acid Desaturation Links Germ Cell Loss to Longevity Through NHR-80/HNF4 in C. elegans

(2011) Jérôme Goudeau et al.   PLOS BIOLOGY

Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains

(2010) Magalie S. Leduc et al.   AGING CELL

Trehalose extends longevity in the nematode Caenorhabditis elegans

(2010) Yoko Honda et al.   AGING CELL

A pathway that links reproductive status to lifespan in Caenorhabditis elegans

(2010) Cynthia Kenyon   Annals of the New York Academy of Sciences

Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan

(2010) Kathleen J. Dumas et al.   DEVELOPMENTAL BIOLOGY

Structural diversity of cytochrome P450 enzyme system

(2010) Tsuneo Omura   JOURNAL OF BIOCHEMISTRY

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Database resources of the National Center for Biotechnology Information

(2010) E. W. Sayers et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans Generates Biologically Relevant Levels of Genotoxic Metabolites from Aflatoxin B1 but Not Benzo[a]pyrene In Vivo

(2010) Maxwell C. K. Leung et al.   TOXICOLOGICAL SCIENCES

The Somatic Reproductive Tissues of C. elegans Promote Longevity through Steroid Hormone Signaling

(2010) Tracy M. Yamawaki et al.   PLOS BIOLOGY

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

(2009) Seung-Jae Lee et al.   CURRENT BIOLOGY

Methylation of the Sterol Nucleus by STRM-1 Regulates Dauer Larva Formation in Caenorhabditis elegans

(2009) J. Thomas Hannich et al.   DEVELOPMENTAL CELL

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

In search for function of two human orphan SDR enzymes: Hydroxysteroid dehydrogenase like 2 (HSDL2) and short-chain dehydrogenase/reductase-orphan (SDR-O)

(2009) Dorota Kowalik et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Synthesis and Activity of Dafachronic Acid Ligands for theC. elegansDAF-12 Nuclear Hormone Receptor

(2009) Kamalesh K. Sharma et al.   MOLECULAR ENDOCRINOLOGY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Biosynthesis of theCaenorhabditis elegansdauer pheromone

(2009) Rebecca A. Butcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytochrome P450-dependent metabolism of eicosapentaenoic acid in the nematode Caenorhabditis elegans

(2008) Jana Kulas et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Medium- and short-chain dehydrogenase/reductase gene and protein families

(2008) K. L. Kavanagh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Conserved Endocrine Mechanism Controls the Formation of Dauer and Infective Larvae in Nematodes

(2008) Akira Ogawa et al.   CURRENT BIOLOGY

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans

(2008) D. S. Patel et al.   DEVELOPMENT

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT