标题
Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2016–2020)
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume -, Issue -, Pages -
出版商
Informa UK Limited
发表日期
2021-01-18
DOI
10.1080/13543776.2021.1874345
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Liposomal formulation of HIF-1α inhibitor echinomycin eliminates established metastases of triple-negative breast cancer
- (2020) Christopher M. Bailey et al. Nanomedicine-Nanotechnology Biology and Medicine
- Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells
- (2019) Joan Fernandez Esmerats et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Berberine and barberry (Berberis vulgaris ): A clinical review
- (2019) Mohsen Imenshahidi et al. PHYTOTHERAPY RESEARCH
- HIF Inhibitors: Status of Current Clinical Development
- (2019) Jaleh Fallah et al. Current Oncology Reports
- Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
- (2019) Strowitzki et al. Cells
- 3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
- (2019) Rui Xu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Allosteric inhibition of HIF-2α as a novel therapy for clear cell renal cell carcinoma
- (2019) Yancheng Yu et al. DRUG DISCOVERY TODAY
- Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges
- (2019) Muhammad Zaeem Noman et al. Cells
- Mechanisms of ischaemic neural progenitor proliferation: a regulatory role of the HIF‐1α‐CBX7 pathway
- (2019) H.‐Y. Chiu et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration
- (2018) Liwei Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
- (2018) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy
- (2018) Hongchan An et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)
- (2018) Paul M. Wehn et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit
- (2017) Matthew G. Costales et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth
- (2017) Hyun Seung Ban et al. Cell Death & Disease
- Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes
- (2016) Hyun Seung Ban et al. BIOCONJUGATE CHEMISTRY
- A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
- (2016) Eli M. Wallace et al. CANCER RESEARCH
- Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015)
- (2016) Hyun Seung Ban et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Heat Shock Proteins Promote Cancer: It's a Protection Racket
- (2016) Stuart K. Calderwood et al. TRENDS IN BIOCHEMICAL SCIENCES
- Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound
- (2016) Kyunghye Park et al. Oncotarget
- Total synthesis of (−)-deguelin via an iterative pyran-ring formation strategy
- (2015) Seungbeom Lee et al. CHEMICAL COMMUNICATIONS
- Structural Elucidation and Synthesis of Eudistidine A: An Unusual Polycyclic Marine Alkaloid that Blocks Interaction of the Protein Binding Domains of p300 and HIF-1α
- (2015) Susanna T. S. Chan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive component in Herba Epimedii
- (2015) Chenrui Li et al. LIFE SCIENCES
- The role of hypoxia-inducible factor-2 in digestive system cancers
- (2015) J Zhao et al. Cell Death & Disease
- Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis
- (2014) Yatrik M. Shah et al. GASTROENTEROLOGY
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth
- (2013) Noel A Warfel et al. CELL CYCLE
- Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors
- (2013) Hidemitsu Minegishi et al. ACS Medicinal Chemistry Letters
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage
- (2012) F. Relaix et al. DEVELOPMENT
- Design, Synthesis, and Biological Evaluation of Novel Deguelin-Based Heat Shock Protein 90 (HSP90) Inhibitors Targeting Proliferation and Angiogenesis
- (2012) Dong-Jo Chang et al. JOURNAL OF MEDICINAL CHEMISTRY
- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition
- (2010) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency
- (2009) Yatrik M. Shah et al. Cell Metabolism
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now