标题
A comprehensive review on potential therapeutics interventions for COVID-19
作者
关键词
COVID-19, SARS-CoV-2, Therapeutic targets, Re-purposed drugs, Vaccines
出版物
EUROPEAN JOURNAL OF PHARMACOLOGY
Volume 890, Issue -, Pages 173741
出版商
Elsevier BV
发表日期
2020-11-20
DOI
10.1016/j.ejphar.2020.173741
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses
- (2020) Tuan M. Nguyen et al. CELL RESEARCH
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
- (2020) Manli Wang et al. CELL RESEARCH
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
- (2020) Hussin A. Rothan et al. JOURNAL OF AUTOIMMUNITY
- Emerging coronaviruses: Genome structure, replication, and pathogenesis
- (2020) Yu Chen et al. JOURNAL OF MEDICAL VIROLOGY
- Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle
- (2020) Hongzhou Lu et al. JOURNAL OF MEDICAL VIROLOGY
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- SARS-CoV-2 is an appropriate name for the new coronavirus
- (2020) Yuntao Wu et al. LANCET
- Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
- (2020) Guangdi Li et al. NATURE REVIEWS DRUG DISCOVERY
- First Case of 2019 Novel Coronavirus in the United States
- (2020) Michelle L. Holshue et al. NEW ENGLAND JOURNAL OF MEDICINE
- The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
- (2020) Matteo Chinazzi et al. SCIENCE
- Pathological findings of COVID-19 associated with acute respiratory distress syndrome
- (2020) Zhe Xu et al. Lancet Respiratory Medicine
- On the origin and continuing evolution of SARS-CoV-2
- (2020) Xiaolu Tang et al. National Science Review
- Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
- (2020) Michael Letko et al. Nature Microbiology
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
- (2020) Canrong Wu et al. Acta Pharmaceutica Sinica B
- Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks
- (2020) Hossam M. Ashour et al. Pathogens
- Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review
- (2020) N. M. Wilson et al. ANAESTHESIA
- COVID-19 infection and rheumatoid arthritis: Faraway, so close!
- (2020) Ennio Giulio Favalli et al. AUTOIMMUNITY REVIEWS
- Current pharmacological treatments for COVID‐19: What's next?
- (2020) Cristina Scavone et al. BRITISH JOURNAL OF PHARMACOLOGY
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019‐nCoV Infection
- (2020) Yin‐Xiao Du et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak
- (2020) Tao Zhang et al. CURRENT BIOLOGY
- The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
- (2020) Francesca Coperchini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
- (2020) Chenguang Shen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Public Health Approach of Ayurveda and Yoga for COVID-19 Prophylaxis
- (2020) Girish Tillu et al. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
- Deployment of convalescent plasma for the prevention and treatment of COVID-19
- (2020) Evan M. Bloch et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in Patients With Coronavirus Disease 2019
- (2020) Qing-Lei Zeng et al. JOURNAL OF INFECTIOUS DISEASES
- Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial
- (2020) Richard O Phillips et al. LANCET
- A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
- (2020) Markus Hoffmann et al. MOLECULAR CELL
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- The proximal origin of SARS-CoV-2
- (2020) Kristian G. Andersen et al. NATURE MEDICINE
- Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
- (2020) Irani Thevarajan et al. NATURE MEDICINE
- The COVID-19 vaccine development landscape
- (2020) Tung Thanh Le et al. NATURE REVIEWS DRUG DISCOVERY
- COVID-19: faecal–oral transmission?
- (2020) Jordan Hindson Nature Reviews Gastroenterology & Hepatology
- Remdesivir for 5 or 10 Days in Patients with Severe Covid-19
- (2020) Jason D. Goldman et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
- (2020) Bin Cao et al. NEW ENGLAND JOURNAL OF MEDICINE
- Developing Covid-19 Vaccines at Pandemic Speed
- (2020) Nicole Lurie et al. NEW ENGLAND JOURNAL OF MEDICINE
- Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease
- (2020) Rachel M. Golonka et al. PHYSIOLOGICAL GENOMICS
- Cell entry mechanisms of SARS-CoV-2
- (2020) Jian Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effective treatment of severe COVID-19 patients with tocilizumab
- (2020) Xiaoling Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effectiveness of convalescent plasma therapy in severe COVID-19 patients
- (2020) Kai Duan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of an inactivated vaccine candidate for SARS-CoV-2
- (2020) Qiang Gao et al. SCIENCE
- Immunogenicity of a DNA vaccine candidate for COVID-19
- (2020) Trevor R. F. Smith et al. Nature Communications
- The hallmarks of COVID-19 disease
- (2020) Daolin Tang et al. PLoS Pathogens
- Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19)
- (2020) Samuel James Brake et al. Journal of Clinical Medicine
- Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study
- (2020) Qingxian Cai et al. Engineering
- Use of Remdesivir for Pregnant Patients with Severe Novel 2019 Coronavirus Disease
- (2020) Irogue Igbinosa et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19
- (2020) Samia Arshad et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Therapeutic potential of ciclesonide inhalation for COVID-19 pneumonia: Report of three cases
- (2020) Keisuke Iwabuchi et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- An mRNA Vaccine against SARS-CoV-2 — Preliminary Report
- (2020) Lisa A. Jackson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Quest for a COVID-19 Cure by Repurposing Small-Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply
- (2020) Chris De Savi et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study
- (2020) Ruocong Yang et al. PHARMACOLOGICAL RESEARCH
- Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19)
- (2020) Giuseppe Lippi et al. RESPIRATORY MEDICINE
- The inhaled steroid ciclesonide blocks SARS-CoV-2 RNA replication by targeting the viral replication-transcription complex in cultured cells
- (2020) Shutoku Matsuyama et al. JOURNAL OF VIROLOGY
- Ayurvedic treatment of COVID-19/SARS-CoV-2: A case report
- (2020) P.L.T. Girija et al. Journal of Ayurveda and Integrative Medicine
- RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux
- (2019) Leandro Silva da Costa et al. Cell Death & Disease
- The Molecular Aspect of Antitumor Effects of Protease Inhibitor Nafamostat Mesylate and Its Role in Potential Clinical Applications
- (2019) Xi Chen et al. Frontiers in Oncology
- Favipiravir as a potential countermeasure against neglected and emerging RNA viruses
- (2018) Leen Delang et al. ANTIVIRAL RESEARCH
- Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
- (2017) Timothy P. Sheahan et al. Science Translational Medicine
- Baricitinib in rheumatoid arthritis: evidence-to-date and clinical potential
- (2017) Bindee Kuriya et al. Therapeutic Advances in Musculoskeletal Disease
- Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
- (2016) Rudragouda Channappanavar et al. Cell Host & Microbe
- Baricitinib in Patients with Refractory Rheumatoid Arthritis
- (2016) Mark C. Genovese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol
- (2016) Rameshwar U. Kadam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Correction: Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea
- (2016) Daouda Sissoko et al. PLOS MEDICINE
- Combination therapy with lopinavir/ritonavir, ribavirin and interferon-alpha for Middle East respiratory syndrome: a case report
- (2015) Uh Jin Kim et al. ANTIVIRAL THERAPY
- Arbidol as a broad-spectrum antiviral: An update
- (2014) Julie Blaising et al. ANTIVIRAL RESEARCH
- Recent Advances on Plasmin Inhibitors for the Treatment of Fibrinolysis-Related Disorders
- (2014) Rami A. Al-Horani et al. MEDICINAL RESEARCH REVIEWS
- Indian Traditional Ayurvedic System of Medicine and Nutritional Supplementation
- (2013) M. M. Pandey et al. Evidence-based Complementary and Alternative Medicine
- Simultaneous Treatment of Human Bronchial Epithelial Cells with Serine and Cysteine Protease Inhibitors Prevents Severe Acute Respiratory Syndrome Coronavirus Entry
- (2012) M. Kawase et al. JOURNAL OF VIROLOGY
- Preadmission Use of Inhaled Corticosteroids Is Associated With a Reduced Risk of Direct Acute Lung Injury/Acute Respiratory Distress Syndrome
- (2011) Enrique Ortiz-Diaz et al. CHEST
- Early Use of Glucocorticoids Was a Risk Factor for Critical Disease and Death From pH1N1 Infection
- (2011) K. Han et al. CLINICAL INFECTIOUS DISEASES
- Tocilizumab
- (2010) Adith Venkiteshwaran mAbs
- Tocilizumab
- (2009) Vicki Oldfield et al. DRUGS
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