Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
出版年份 2020 全文链接
标题
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
作者
关键词
-
出版物
EMBO JOURNAL
Volume -, Issue -, Pages -
出版商
EMBO
发表日期
2020-12-23
DOI
10.15252/embj.2020105001
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
- (2020) Erik W. Martin et al. SCIENCE
- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation
- (2019) Brian Tsang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease
- (2019) Natalia B. Nedelsky et al. Nature Reviews Neurology
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
- (2019) Tae Hun Kim et al. SCIENCE
- Physiological, Pathological, and Targetable Membraneless Organelles in Neurons
- (2019) Veronica H. Ryan et al. TRENDS IN NEUROSCIENCES
- Targeting Fyn Kinase in Alzheimer’s Disease
- (2018) Haakon B. Nygaard BIOLOGICAL PSYCHIATRY
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
- (2018) Ailin Wang et al. EMBO JOURNAL
- Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior
- (2018) Titus Franzmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RGG/RG Motif Regions in RNA Binding and Phase Separation
- (2018) P. Andrew Chong et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation
- (2018) Veronica H. Ryan et al. MOLECULAR CELL
- Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model
- (2018) Levi M. Smith et al. NEUROPHARMACOLOGY
- Sequence determinants of protein phase behavior from a coarse-grained model
- (2018) Gregory L. Dignon et al. PLoS Computational Biology
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- The SH3 domain of Fyn kinase interacts with and induces liquid–liquid phase separation of the low-complexity domain of hnRNPA2
- (2018) Joshua Amaya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration
- (2018) Saba N. Baskoylu et al. PLoS Genetics
- Genetic mutations in RNA-binding proteins and their roles in ALS
- (2017) Katannya Kapeli et al. HUMAN GENETICS
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
- (2017) Keiko Imamura et al. Science Translational Medicine
- Determinants of affinity and specificity in RNA-binding proteins
- (2016) Stephanie Helder et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- mScarlet: a bright monomeric red fluorescent protein for cellular imaging
- (2016) Daphne S Bindels et al. NATURE METHODS
- Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System
- (2016) Fernando J. Martinez et al. NEURON
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
- (2015) Adam C. Kaufman et al. ANNALS OF NEUROLOGY
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition
- (2014) A. K. Lancaster et al. BIOINFORMATICS
- NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
- (2014) Woonghee Lee et al. BIOINFORMATICS
- Transport and translation of MBP mRNA is regulated differently by distinct hnRNP proteins
- (2014) J. Torvund-Jensen et al. JOURNAL OF CELL SCIENCE
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
- (2014) Peter V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- Fyn kinase inhibition as a novel therapy for Alzheimer’s disease
- (2014) Haakon B Nygaard et al. Alzheimers Research & Therapy
- The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules
- (2013) Kyota Yasuda et al. JOURNAL OF CELL BIOLOGY
- Forcefield_PTM: Ab Initio Charge and AMBER Forcefield Parameters for Frequently Occurring Post-Translational Modifications
- (2013) George A. Khoury et al. Journal of Chemical Theory and Computation
- A Simple Atomic-Level Hydrophobicity Scale Reveals Protein Interfacial Structure
- (2013) Lauren H. Kapcha et al. JOURNAL OF MOLECULAR BIOLOGY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Motor neuron involvement in multisystem proteinopathy: Implications for ALS
- (2013) M. Benatar et al. NEUROLOGY
- Making myelin basic protein -from mRNA transport to localized translation
- (2013) Christina Müller et al. Frontiers in Cellular Neuroscience
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- A TOG: -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
- (2012) P. Ayaz et al. SCIENCE
- Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
- (2012) Boris Rogelj et al. Scientific Reports
- Heterogeneous Nuclear Ribonucleoprotein (hnRNP) F Is a Novel Component of Oligodendroglial RNA Transport Granules Contributing to Regulation of Myelin Basic Protein (MBP) Synthesis
- (2011) Robin White et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K
- (2011) Lisbeth S. Laursen et al. JOURNAL OF CELL BIOLOGY
- Transient, Sparsely Populated Compact States of Apo and Calcium-Loaded Calmodulin Probed by Paramagnetic Relaxation Enhancement: Interplay of Conformational Selection and Induced Fit
- (2011) Nicholas J. Anthis et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements
- (2011) Chandrasekhar S. Raju et al. MOLECULAR BIOLOGY OF THE CELL
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- MosSCI and Gateway Compatible Plasmid Toolkit for Constitutive and Inducible Expression of Transgenes in the C. elegans Germline
- (2011) Eva Zeiser et al. PLoS One
- Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
- (2009) A. D'Ambrogio et al. NUCLEIC ACIDS RESEARCH
- The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia
- (2008) Ian RA Mackenzie et al. CURRENT OPINION IN NEUROLOGY
- Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules
- (2008) Robin White et al. JOURNAL OF CELL BIOLOGY
- Multiplexed Dendritic Targeting of α Calcium Calmodulin-dependent Protein Kinase II, Neurogranin, and Activity-regulated Cytoskeleton-associated Protein RNAs by the A2 Pathway
- (2008) Yuanzheng Gao et al. MOLECULAR BIOLOGY OF THE CELL
- Coarse-grained Models for Simulations of Multiprotein Complexes: Application to Ubiquitin Binding
- (2007) Young C. Kim et al. JOURNAL OF MOLECULAR BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search