标题
Genetic mutations in RNA-binding proteins and their roles in ALS
作者
关键词
-
出版物
HUMAN GENETICS
Volume 136, Issue 9, Pages 1193-1214
出版商
Springer Nature
发表日期
2017-07-31
DOI
10.1007/s00439-017-1830-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes
- (2017) Arianna Russo et al. HUMAN MOLECULAR GENETICS
- Effects of Mutations on the Aggregation Propensity of the Human Prion-Like Protein hnRNPA2B1
- (2017) Kacy R. Paul et al. MOLECULAR AND CELLULAR BIOLOGY
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- RNA phase transitions in repeat expansion disorders
- (2017) Ankur Jain et al. NATURE
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice
- (2017) Ting-Yuan Liu et al. Open Biology
- Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS
- (2016) Marisa Kamelgarn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis
- (2016) Yulei Shang et al. BRAIN RESEARCH
- C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
- (2016) Kyung-Ha Lee et al. CELL
- EWSR1 regulates mitosis by dynamically influencing microtubule acetylation
- (2016) Yi-Long Wang et al. CELL CYCLE
- FUS-linked essential tremor associated with motor dysfunction in Drosophila
- (2016) Murni Tio et al. HUMAN GENETICS
- Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins
- (2016) Antonia Ratti et al. JOURNAL OF NEUROCHEMISTRY
- Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors
- (2016) B. Kolisnyk et al. JOURNAL OF NEUROSCIENCE
- hnRNPA1 autoregulates its own mRNA expression to remain non-cytotoxic
- (2016) Hiroaki Suzuki et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Comprehensive Identification of RNA-Binding Domains in Human Cells
- (2016) Alfredo Castello et al. MOLECULAR CELL
- The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
- (2016) Wenzhang Wang et al. NATURE MEDICINE
- Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS
- (2016) Qing Liu et al. NEUROLOGY
- Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System
- (2016) Fernando J. Martinez et al. NEURON
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses
- (2016) Katannya Kapeli et al. Nature Communications
- ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
- (2016) Aarti Sharma et al. Nature Communications
- In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes
- (2016) Hermann Broder Schmidt et al. Cell Reports
- Pathogenesis of FUS-associated ALS and FTD: insights from rodent models
- (2016) Matthew Nolan et al. Acta Neuropathologica Communications
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
- (2015) Claudio R. Alarcón et al. CELL
- Inverse Size Scaling of the Nucleolus by a Concentration-Dependent Phase Transition
- (2015) Stephanie C. Weber et al. CURRENT BIOLOGY
- ALS-linked mutations in ubiquilin-2 or hnRNPA1 reduce interaction between ubiquilin-2 and hnRNPA1
- (2015) Kathleen M. Gilpin et al. HUMAN MOLECULAR GENETICS
- Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
- (2015) Yuan Lin et al. MOLECULAR CELL
- ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
- (2015) Tetsuro Murakami et al. NEURON
- Nucleic acid-binding specificity of human FUS protein
- (2015) Xueyin Wang et al. NUCLEIC ACIDS RESEARCH
- The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics
- (2015) Shana Elbaum-Garfinkle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
- (2015) J. Chew et al. SCIENCE
- RNA-binding proteins in neurodegeneration: Seq and you shall receive
- (2015) Julia K. Nussbacher et al. TRENDS IN NEUROSCIENCES
- ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
- (2015) Shuying Sun et al. Nature Communications
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- Programmed Translational Readthrough Generates Antiangiogenic VEGF-Ax
- (2014) Sandeepa M. Eswarappa et al. CELL
- TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1
- (2014) Fang He et al. HUMAN MOLECULAR GENETICS
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
- (2014) Haiyan Qiu et al. JOURNAL OF CLINICAL INVESTIGATION
- ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor
- (2014) L. Liu-Yesucevitz et al. JOURNAL OF NEUROSCIENCE
- Selective interactions of hnRNP M isoforms with the TET proteins TAF15 and TLS/FUS
- (2014) Marija Marko et al. MOLECULAR BIOLOGY REPORTS
- The role of FUS gene variants in neurodegenerative diseases
- (2014) Hao Deng et al. Nature Reviews Neurology
- No mutations in hnRNPA1 and hnRNPA2B1 in Dutch patients with amyotrophic lateral sclerosis, frontotemporal dementia, and inclusion body myopathy
- (2014) Meinie Seelen et al. NEUROBIOLOGY OF AGING
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP-43-positive inclusions
- (2014) Hiroyuki Honda et al. NEUROPATHOLOGY
- Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones
- (2014) J. Robin Highley et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- An essential role for Ewing sarcoma gene (EWS) in early white adipogenesis
- (2014) Jun Hong Park et al. Obesity
- hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains
- (2013) Ilmin Kwon et al. CELL
- A Multifunctional Protein, EWS, Is Essential for Early Brown Fat Lineage Determination
- (2013) Jun Hong Park et al. DEVELOPMENTAL CELL
- A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion proteins
- (2013) Christer Thomsen et al. FASEB JOURNAL
- Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma
- (2013) Eva Bentmann et al. FEBS Journal
- The diversity of soft tissue tumours withEWSR1gene rearrangements: a review
- (2013) Cyril Fisher HISTOPATHOLOGY
- ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN
- (2013) Ewout J.N. Groen et al. HUMAN MOLECULAR GENETICS
- ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
- (2013) Caroline Vance et al. HUMAN MOLECULAR GENETICS
- hnRNP A1: The Swiss Army Knife of Gene Expression
- (2013) Jacques Jean-Philippe et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stress granules as crucibles of ALS pathogenesis
- (2013) Yun R. Li et al. JOURNAL OF CELL BIOLOGY
- TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress
- (2013) Shinji Higashi et al. JOURNAL OF NEUROCHEMISTRY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
- (2013) Wen-Yuan Wang et al. NATURE NEUROSCIENCE
- hnRNPA2B1 and hnRNPA1 mutations are rare in patients with “multisystem proteinopathy” and frontotemporal lobar degeneration phenotypes
- (2013) Isabelle Le Ber et al. NEUROBIOLOGY OF AGING
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
- (2013) Carolina Villarroya-Beltri et al. Nature Communications
- Identification of In Vivo, Conserved, TAF15 RNA Binding Sites Reveals the Impact of TAF15 on the Neuronal Transcriptome
- (2013) Fadia Ibrahim et al. Cell Reports
- ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
- (2013) Yueqin Zhou et al. PLoS Genetics
- Misregulated RNA processing in amyotrophic lateral sclerosis
- (2012) Magdalini Polymenidou et al. BRAIN RESEARCH
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
- (2012) Tina W. Han et al. CELL
- Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
- (2012) Alfredo Castello et al. CELL
- Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice
- (2012) Amit Berson et al. EMBO Molecular Medicine
- FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
- (2012) J. C. Schwartz et al. GENES & DEVELOPMENT
- Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis
- (2012) Julien Couthouis et al. HUMAN MOLECULAR GENETICS
- RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations
- (2012) J. G. Daigle et al. HUMAN MOLECULAR GENETICS
- Accelerated Disease Onset with Stabilized Familial Amyotrophic Lateral Sclerosis (ALS)-linked Mutant TDP-43 Proteins
- (2012) Shoji Watanabe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells
- (2012) Claudia Colombrita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel TARDBP mutations in Nordic ALS patients
- (2012) Huei-Hsin Chiang et al. JOURNAL OF HUMAN GENETICS
- FUS/TLS-immunoreactive Neuronal and Glial Cell Inclusions Increase With Disease Duration in Familial Amyotrophic Lateral Sclerosis With an R521CFUS/TLSMutation
- (2012) Naoki Suzuki et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- RNA-mediated toxicity in neurodegenerative disease
- (2012) Veronique V. Belzil et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- hnRNP A1 Proofreads 3′ Splice Site Recognition by U2AF
- (2012) Joao Paulo Tavanez et al. MOLECULAR CELL
- Systematic discovery of structural elements governing stability of mammalian messenger RNAs
- (2012) Hani Goodarzi et al. NATURE
- Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
- (2012) Clotilde Lagier-Tourenne et al. NATURE NEUROSCIENCE
- Screening of the TARDBP gene in familial and sporadic amyotrophic lateral sclerosis patients of Chinese origin
- (2012) Zhang-Yu Zou et al. NEUROBIOLOGY OF AGING
- Extensive genetics of ALS: A population-based study in Italy
- (2012) A. Chio et al. NEUROLOGY
- FUS-NLS/Transportin 1 Complex Structure Provides Insights into the Nuclear Targeting Mechanism of FUS and the Implications in ALS
- (2012) Chunyan Niu et al. PLoS One
- Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
- (2012) Zi Chao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
- (2012) Shinsuke Ishigaki et al. Scientific Reports
- Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
- (2012) Boris Rogelj et al. Scientific Reports
- Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins
- (2012) Stephanie C. Huelga et al. Cell Reports
- Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation
- (2011) Ian R. A. Mackenzie et al. ACTA NEUROPATHOLOGICA
- The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene
- (2011) Julie S. Snowden et al. ACTA NEUROPATHOLOGICA
- Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis
- (2011) N. Ticozzi et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- PGC-1α Regulates Translocated in Liposarcoma Activity: Role in Oxidative Stress Gene Expression
- (2011) Cristina Sánchez-Ramos et al. ANTIOXIDANTS & REDOX SIGNALING
- A fraction of the transcription factor TAF15 participates in interactions with a subset of the spliceosomal U1 snRNP complex
- (2011) Michael Leichter et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
- (2011) Manuela Neumann et al. BRAIN
- High frequency of the TARDBP p.Ala382Thr mutation in Sardinian patients with amyotrophic lateral sclerosis
- (2011) S Orrù et al. CLINICAL GENETICS
- Spatial code recognition in neuronal RNA targeting: Role of RNA–hnRNP A2 interactions
- (2011) Ilham A. Muslimov et al. JOURNAL OF CELL BIOLOGY
- Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
- (2011) Lionel M. Igaz et al. JOURNAL OF CLINICAL INVESTIGATION
- UG Repeats/TDP-43 Interactions near 5′ Splice Sites Exert Unpredictable Effects on Splicing Modulation
- (2011) Monica Passoni et al. JOURNAL OF MOLECULAR BIOLOGY
- Local RNA Translation at the Synapse and in Disease
- (2011) L. Liu-Yesucevitz et al. JOURNAL OF NEUROSCIENCE
- RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS
- (2011) Shangxi Xiao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements
- (2011) Chandrasekhar S. Raju et al. MOLECULAR BIOLOGY OF THE CELL
- Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
- (2011) Han-Xiang Deng et al. NATURE
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
- (2011) Edward B. Lee et al. NATURE REVIEWS NEUROSCIENCE
- RNA targets of wild-type and mutant FET family proteins
- (2011) Jessica I Hoell et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- FUS and TDP43 genetic variability in FTD and CBS
- (2011) Edward D. Huey et al. NEUROBIOLOGY OF AGING
- Different clinical and neuropathologic phenotypes of familial ALS with A315E TARDBP mutation
- (2011) Y. Fujita et al. NEUROLOGY
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
- (2011) Fabienne C. Fiesel et al. NUCLEIC ACIDS RESEARCH
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A yeast functional screen predicts new candidate ALS disease genes
- (2011) J. Couthouis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis
- (2010) Brian C. Kraemer et al. ACTA NEUROPATHOLOGICA
- FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration
- (2010) Hazel Urwin et al. ACTA NEUROPATHOLOGICA
- Enlarging clinical spectrum of FALS with TARDBP gene mutations: S393L variant in an Italian family showing phenotypic variability and relevance for genetic counselling
- (2010) Paola Origone et al. Amyotrophic Lateral Sclerosis
- FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
- (2010) Han-Xiang Deng et al. ANNALS OF NEUROLOGY
- Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS
- (2010) Daisuke Ito et al. ANNALS OF NEUROLOGY
- Ewing sarcoma gene Ews regulates hematopoietic stem cell senescence
- (2010) J. Cho et al. BLOOD
- Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay
- (2010) Nicholas J McGlincy et al. BMC GENOMICS
- Association between novel TARDBP mutations and Chinese patients with amyotrophic lateral sclerosis
- (2010) Hui-Ling Xiong et al. BMC Medical Genetics
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
- (2010) Dorothee Dormann et al. EMBO JOURNAL
- Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
- (2010) Daryl A. Bosco et al. HUMAN MOLECULAR GENETICS
- TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
- (2010) C. Lagier-Tourenne et al. HUMAN MOLECULAR GENETICS
- Familial ALS with G298S Mutation in TARDBP: A Comparison of CSF Tau Protein Levels with those in Sporadic ALS
- (2010) Ichiro Nozaki et al. INTERNAL MEDICINE
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
- (2010) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyotrophic Lateral Sclerosis-associated Proteins TDP-43 and FUS/TLS Function in a Common Biochemical Complex to Co-regulate HDAC6 mRNA
- (2010) Sang Hwa Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prion-like disorders: blurring the divide between transmissibility and infectivity
- (2010) M. Cushman et al. JOURNAL OF CELL SCIENCE
- SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations
- (2010) S. Millecamps et al. JOURNAL OF MEDICAL GENETICS
- The clinical and neuroanatomical phenotype of FUS associated frontotemporal lobar degeneration
- (2010) J. D. Rohrer et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis
- (2010) S. J. Barmada et al. JOURNAL OF NEUROSCIENCE
- TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
- (2010) Ian RA Mackenzie et al. LANCET NEUROLOGY
- Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis
- (2010) Gracjan Michlewski et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- FUS, TARDBP, and SOD1 mutations in a Taiwanese cohort with familial ALS
- (2010) Ching-Paio Tsai et al. NEUROBIOLOGY OF AGING
- Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
- (2010) Jozsef Gal et al. NEUROBIOLOGY OF AGING
- Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese
- (2010) Aritoshi Iida et al. NEUROBIOLOGY OF AGING
- Genetic contribution of FUS to frontotemporal lobar degeneration
- (2010) T. Van Langenhove et al. NEUROLOGY
- Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies
- (2010) Felix Geser et al. NEUROPATHOLOGY
- Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations
- (2010) Yoshihiro Kino et al. NUCLEIC ACIDS RESEARCH
- TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity
- (2010) Aaron Voigt et al. PLoS One
- ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
- (2010) S.-C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
- (2010) C. V. Clower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease
- (2009) Manuela Neumann et al. ACTA NEUROPATHOLOGICA
- A new subtype of frontotemporal lobar degeneration with FUS pathology
- (2009) M. Neumann et al. BRAIN
- FUS-Immunoreactive Intranuclear Inclusions in Neurodegenerative Disease
- (2009) John Woulfe et al. BRAIN PATHOLOGY
- The role of RNP biogenesis in spinal muscular atrophy
- (2009) Ashwin Chari et al. CURRENT OPINION IN CELL BIOLOGY
- TARDBP(TDP-43) sequence analysis in patients with familial and sporadic ALS: identification of two novel mutations
- (2009) R. Del Bo et al. EUROPEAN JOURNAL OF NEUROLOGY
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- High frequency ofTARDBPgene mutations in Italian patients with amyotrophic lateral sclerosis
- (2009) Lucia Corrado et al. HUMAN MUTATION
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 M311V mutation in familial amyotrophic lateral sclerosis
- (2009) R Lemmens et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Analysis of Ewing Sarcoma (EWS)-Binding Proteins: Interaction with hnRNP M, U, and RNA-Helicases p68/72 within Protein−RNA Complexes
- (2009) Steffen Pahlich et al. JOURNAL OF PROTEOME RESEARCH
- Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
- (2009) Brian D. Freibaum et al. JOURNAL OF PROTEOME RESEARCH
- Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis
- (2009) Masaki Kamada et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Genome-wide Analysis of Alternative Pre-mRNA Splicing and RNA-Binding Specificities of the Drosophila hnRNP A/B Family Members
- (2009) Marco Blanchette et al. MOLECULAR CELL
- Mutational analysis of TARDBP in neurodegenerative diseases
- (2009) Nicola Ticozzi et al. NEUROBIOLOGY OF AGING
- Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis
- (2009) Janine Kirby et al. NEUROGENETICS
- Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
- (2009) A. D'Ambrogio et al. NUCLEIC ACIDS RESEARCH
- hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection
- (2009) J.-F. Fisette et al. RNA
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- The TET Family of Proteins: Functions and Roles in Disease
- (2009) A. Y. Tan et al. Journal of Molecular Cell Biology
- ALSOD: The Amyotrophic Lateral Sclerosis Online Database
- (2008) Richard Wroe et al. Amyotrophic Lateral Sclerosis
- TDP-43mutation in familial amyotrophic lateral sclerosis
- (2008) Akio Yokoseki et al. ANNALS OF NEUROLOGY
- TDP-43A315T mutation in familial motor neuron disease
- (2008) Michael A. Gitcho et al. ANNALS OF NEUROLOGY
- Two German Kindreds With Familial Amyotrophic Lateral Sclerosis Due to TARDBP Mutations
- (2008) Peter Kühnlein et al. ARCHIVES OF NEUROLOGY
- Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B
- (2008) Yaowu He et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function
- (2008) Laure Jobert et al. EXPERIMENTAL CELL RESEARCH
- Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation
- (2008) Matthew J. Winton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural determinants of the cellular localization and shuttling of TDP-43
- (2008) Y. M. Ayala et al. JOURNAL OF CELL SCIENCE
- TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
- (2008) I.-Fan Wang et al. JOURNAL OF NEUROCHEMISTRY
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
- (2008) Vivianna M Van Deerlin et al. LANCET NEUROLOGY
- Multiplexed Dendritic Targeting of α Calcium Calmodulin-dependent Protein Kinase II, Neurogranin, and Activity-regulated Cytoskeleton-associated Protein RNAs by the A2 Pathway
- (2008) Yuanzheng Gao et al. MOLECULAR BIOLOGY OF THE CELL
- Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops
- (2008) Gracjan Michlewski et al. MOLECULAR CELL
- Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
- (2008) Xiangting Wang et al. NATURE
- Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
- (2008) John C Castle et al. NATURE GENETICS
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression
- (2008) Y. M. Ayala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
- (2008) Nicola J. Rutherford et al. PLoS Genetics
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now