Article
Clinical Neurology
Menghua Wang, Zhongyu Jian, Yucheng Ma, Xi Jin, Hong Li, Kunjie Wang
Summary: This study found that depression might be associated with an increased risk of kidney stones through observational study and Mendelian randomization. Further large prospective cohort studies are needed to validate this finding.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Public, Environmental & Occupational Health
Xing-peng Di, Xiao-shuai Gao, Li-yuan Xiang, Xin Wei
Summary: This study investigated the prevalence of kidney stone disease (KSD) in the US population and examined the association between thiamine and riboflavin intake and KSD. The results showed that higher riboflavin intake was negatively associated with KSD, especially in males. No significant association was found between thiamine intake and KSD.
Article
Urology & Nephrology
Amro A. Harb, David S. Han, Justin A. Lee, Michael L. Schulster, Ojas Shah
Summary: Urinary stone disease is common, affecting approximately 10% of American adults. This study aimed to investigate the role of micronutrient inadequacy in stone formation. The analysis revealed that inadequate intake of vitamin A was associated with stone formation, and inadequate intake of vitamin A and pyridoxine was associated with a higher number of recurrent stones. Further research is needed to understand the roles of these micronutrients and their potential for evaluation and treatment in stone-formers.
Article
Public, Environmental & Occupational Health
Yang Chen, Xudong Shen, Hu Liang, Guoxiang Li, Kexing Han, Chaozhao Liang, Zongyao Hao
Summary: This study aims to explore the effects of HCV on the prevalence rate of kidney stones in US women. The results show a positive relationship between HCV infection and kidney stones, especially among other races and individuals with a BMI within the range of 25-29.9 kg/m2.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Pharmacology & Pharmacy
Xingpeng Di, Liyuan Xiang, Menghua Wang, Xin Wei
Summary: The objective of this investigation was to determine if regular marijuana use is associated with a history of kidney stones in the US population. The study found that regular male marijuana users had a negative association with kidney stones. Consumption of marijuana one to six times per week was negatively related to the risk of kidney stones in males.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Urology & Nephrology
Ye Yuan, Wei Tan, Yinchao Huang, Hao Huang, Yadong Li, Yuanqing Gou, Shengjie Zeng, Zili Hu
Summary: This study found an association between hysterectomy and kidney stone disease through analyzing data from the National Health and Nutrition Examination Survey from 2007 to 2018. After adjusting for potential confounders, hysterectomy was positively associated with the prevalence of kidney stone disease, while younger age at hysterectomy was negatively associated. Consistent with this, genetically predicted hysterectomy was causally associated with a higher risk of kidney stone disease.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Mohammad Abufaraj, Tianlin Xu, Chao Cao, Thomas Waldhoer, Christian Seitz, David D'andrea, Abdelmuez Siyam, Rand Tarawneh, Harun Fajkovic, Eva Schernhammer, Lin Yang, Shahrokh F. Shariat
Summary: Although the prevalence of kidney stones remains higher in adult US men than in women, the trend has been increasing only in women, closing the gender gap in kidney stone prevalence over the past decade.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Nutrition & Dietetics
Anni Wang, Ningrui Wang, Dongfeng Zhang, Jing Wen, Weijing Wang
Summary: A relationship may exist between selenium and kidney calculi, but there is currently a lack of research in this field. Our study investigated the relationship between serum selenium levels and a medical history of kidney stones in adults. Using data from the National Health and Nutrition Examination Survey, we found a negative correlation between serum selenium levels and the risk of kidney stone history. Furthermore, we discovered a nonlinear dose-response relationship between selenium levels and the history of kidney stone disease.
Article
Environmental Sciences
Kajsa Ugelvig Petersen, Katia Keglberg Haervig, Esben Meulengracht Flachs, Jens Peter Bonde, Christian Lindh, Karin Sorig Hougaard, Gunnar Toft, Cecilia Host Ramlau-Hansen, Sandra Sogaard Tottenborg
Summary: This study examined the impact of PFAS exposure on reproductive function in young adult males. The results showed a slight association between higher levels of PFAS and follicle-stimulating hormone (FSH) levels, but no consistent associations with semen quality and testicular volume were found.
ENVIRONMENTAL RESEARCH
(2022)
Article
Immunology
Xingpeng Di, Shaozhuang Liu, Liyuan Xiang, Xi Jin
Summary: This study analyzed the impact of systemic immune-inflammatory index (SII) on kidney stones. The results showed that in US adults aged 20-50, high levels of SII (>330 x 10(9)/L) were positively associated with the risk of kidney stones. However, no difference was found in the elderly subgroup. This finding compensates for previous studies and further validation is needed through larger prospective cohorts.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Nutrition & Dietetics
Minghui Liu, Zhongxiao Cui, Jinbo Chen, Meng Gao, Zewu Zhu, Hequn Chen
Summary: This study evaluated the association between dietary selenium intake and the risk of kidney stones in adults. The findings showed an inverse relation between dietary selenium intake and the risk of kidney stones, especially for younger individuals, males, and overweight/obese individuals. The study provides preliminary guidance on dietary selenium intake for the prevention of kidney stones in different populations.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Jonghee Kim, Joanne F. Dorgan, Hyesook Kim, Oran Kwon, Yangha Kim, Yuri Kim, Kwang Suk Ko, Yoon Jung Park, Hyesook Park, Seungyoun Jung
Summary: The use of nutrition labels is associated with a lower risk of chronic kidney disease, especially in older adults.
Article
Neurosciences
Zhaohao Zeng, Yanmei Cen, Lu Wang, Xiaoguang Luo
Summary: The study aimed to explore the association between Parkinson's disease (PD) and dietary inflammatory index (DII) scores in adults over 40 years old in the US. Data from the NHANES conducted from 2003 to 2018 were analyzed, including 21,994 participants. Logistic regression analysis and propensity score matching were used to investigate the relationship between DII and PD. The results showed a positive association between higher DII scores and PD, suggesting the potential use of diet as an intervention strategy for managing PD.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Ana Florea, Elizabeth T. Jacobs, Robin B. Harris, Yann C. Klimentidis, Bijin Thajudeen, Lindsay N. Kohler
Summary: The study found that in individuals with lab-confirmed CKD, 91.5% answered 'no' to the self-report question; in those without CKD, only 1.1% answered 'yes'. Older individuals and women were more likely to be unaware of their CKD.
JOURNAL OF PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Si Liu, Mingyang Wu, Yan Wang, Lu Xiang, Gang Luo, Qian Lin, Lin Xiao
Summary: This study aimed to investigate the relationship between dietary fiber intake and serum Klotho levels in people aged 40-79 years in the United States. The results showed a significant association between dietary fiber intake and serum Klotho levels, with a stronger correlation observed in older individuals and those who were overweight or obese.
Article
Andrology
Weipu Mao, Hui Zhang, Zhipeng Xu, Jiang Geng, Ziwei Zhang, Jianping Wu, Bin Xu, Ming Chen
Summary: The study found a significant correlation between urine specific gravity and the prevalence rate of kidney stones, with the prevalence rate increasing as urine specific gravity increases. Therefore, urine specific gravity may be an important indicator for early screening of risk factors for kidney stones.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2021)
Letter
Oncology
Weipu Mao, Keyi Wang, Hui Zhang, Haowen Lu, Si Sun, Changxiu Tian, Zonglin Wu, Jianping Wu, Bin Xu, Huae Xu, Bo Peng, Ming Chen
CLINICAL AND TRANSLATIONAL MEDICINE
(2021)
Article
Andrology
Keyi Wang, Weipu Mao, Jinliang Ni, Jinbo Xie, Lei Yin, Houliang Zhang, Tao Zhang, Tianyuan Xu, Bo Peng
Summary: This study aimed to investigate the mechanism of penile damages in experimental autoimmune prostatitis (EAP) rat models, revealing a potential pathological link between chronic prostatitis (CP) and penile damages. The results demonstrated a positive correlation between the severity of prostatitis and the infiltration of inflammatory factors and impaired function in the corpus cavernosum of the penis in EAP rats.
Article
Cell Biology
Heng Shi, Jinbo Xie, Keyi Wang, Weiyi Li, Lei Yin, Guangchun Wang, Zonglin Wu, Jinliang Ni, Weipu Mao, Changcheng Guo, Bo Peng
Summary: This study identified LINC01451 as a functional lncRNA with significantly higher expression in BLCa tissues compared to normal tissues. LINC01451 was found to directly interact with LIN28A and LIN28B, promoting proliferation, invasion, and metastasis of BLCa. Mechanistically, LINC01451 was shown to facilitate epithelial-mesenchymal transition through activating the TGF-beta/Smad signaling pathway, leading to the progression of BLCa.
CELLULAR SIGNALLING
(2021)
Article
Chemistry, Multidisciplinary
Keyi Wang, Yang Zhang, Weipu Mao, Wei Feng, Shuting Lu, Jian Wan, Xinran Song, Yu Chen, Bo Peng
Summary: The study introduces a novel nanozyme CaPB, which mimics the activity of multiple enzymes, effectively clearing harmful substances and inhibiting renal damage, showing potential for treating kidney injury. Additionally, CaPB nanozymes significantly increase the expression of ferroptosis regulator and protect the kidney from oxidative injury, indicating a promising approach for AKI treatment.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Biotechnology & Applied Microbiology
Zhipeng Xu, Hui Chen, Jin Sun, Weipu Mao, Shuqiu Chen, Ming Chen
Summary: This study established a ten-lncRNA signature for predicting bladder cancer recurrence based on multi-omics analysis, which showed robust predictive value in training and testing sets and association with immune disorders.
Article
Oncology
JunJie Yu, WeiPu Mao, Si Sun, Qiang Hu, Can Wang, ZhiPeng Xu, RuiJi Liu, SaiSai Chen, Bin Xu, Ming Chen
Summary: This study aimed to identify an autophagy-related molecular subtype and characterize a novel autophagy-immune related genes score (AI-score) signature and prognosis model in bladder cancer patients. The study utilized public databases and transcriptome cohorts to perform genomic analysis and unsupervised methods. The results revealed the role of the AI-score signature and prognosis model in predicting prognosis and selecting personalized immunotherapy strategies.
CANCER MANAGEMENT AND RESEARCH
(2022)
Article
Oncology
Yidi Wang, Keyi Wang, Jinliang Ni, Houliang Zhang, Lei Yin, Yifan Zhang, Huajuan Shi, Tao Zhang, Naichun Zhou, Weipu Mao, Bo Peng
Summary: This study indicates that C-NLR as a preoperative inflammation index is of significant importance for the therapeutic outcomes of bladder cancer patients undergoing radical cystectomy. C-NLR serves as a reliable predictor of long-term prognosis and plays a crucial role in optimizing individualized therapy for BC patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Qiang Hu, Weipu Mao, Tiange Wu, Zhipeng Xu, Junjie Yu, Can Wang, Saisai Chen, Shuqiu Chen, Bin Xu, Yueshuang Xu, Ming Chen
Summary: In RCC patients undergoing laparoscopic partial or radical nephrectomy, NLR and PLR were identified as biomarkers of systemic inflammation associated with increased risk of sarcopenia. The best cutoff points for predicting sarcopenia risk were NLR >2.88 and PLR >135.63, with higher levels indicating a greater risk. Adjusting for various variables, patients with NLR >2.88 and PLR >135.63 had significantly higher risks of developing sarcopenia compared to those with lower NLR or PLR levels.
FRONTIERS IN ONCOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Si Sun, Weipu Mao, Lilin Wan, Kehao Pan, Liting Deng, Lei Zhang, Guangyuan Zhang, Ming Chen
Summary: This study found that FGF17, PRKCG, SSTR1, and SCTR were metastatic immune-related differentially expressed genes (mIR-DEGs) with independent prognostic values in renal clear cell carcinoma. These genes were significantly associated with clinicopathological factors and immune checkpoint-related genes. The risk prognostic model based on these genes showed good predictive potential.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Nutrition & Dietetics
Weipu Mao, Keyi Wang, Yuan Wu, Jinliang Ni, Houliang Zhang, Yidi Wang, Zonglin Wu, Ruiji Liu, Jiang Geng, Shuqiu Chen, Ming Chen
Summary: This study assessed the prognostic value of the advanced lung cancer inflammatory index (ALI) and modified ALI (mALI) in patients with renal cell carcinoma (RCC). Low ALI and low mALI were associated with poorer prognosis in RCC patients undergoing laparoscopic nephrectomy. Preoperative mALI can be used as a potential independent prognostic indicator for RCC patients.
FRONTIERS IN NUTRITION
(2022)
Article
Surgery
Si Sun, Weipu Mao, Shuchun Tao, Lilin Wan, Xiangyu Zou, Guangyuan Zhang, Ming Chen
Summary: The aim of this study was to assess the effect of preoperative blood glucose levels on the length of stay in patients with kidney stones undergoing percutaneous nephrolithotomy. The results demonstrated that higher preoperative blood glucose levels were significantly associated with longer length of stay in these patients.
FRONTIERS IN SURGERY
(2022)
Article
Environmental Sciences
Jinliang Ni, Ziye Li, Yi Lu, Houliang Zhang, Guangchun Wang, Jinbo Xie, Jun Xie, Yidi Wang, Yifan Zhang, Keyi Wang, Weipu Mao, Bo Peng
Summary: Exposure to nephrotoxic metals such as cadmium and lead is associated with the occurrence of urinary incontinence in women.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biotechnology & Applied Microbiology
Keyi Wang, Yongzhe Gu, Jinliang Ni, Houliang Zhang, Yidi Wang, Yifan Zhang, Xianchao Sun, Tianyuan Xu, Weipu Mao, Bo Peng
Summary: This study reveals that decreased expression of ZNF268 is associated with tumor progression and poor prognosis in ccRCC. Overexpression of ZNF268 inhibits tumor cell proliferation, migration, and invasion, and promotes apoptosis. Moreover, ZNF268 expression is positively correlated with immune cell infiltration in the tumor. The study also suggests a potential regulatory axis of AC093157.1/miR-27a-3p in modulating ZNF268 function in ccRCC.
Review
Oncology
Rui-Ji Liu, Qiang Hu, Shu-Ying Li, Wei-Pu Mao, Bin Xu, Ming Chen
Summary: AR-V7 expression indicates poor prognosis and is an independent risk factor for OS in AA/E-treated mCRPC patients, but plays a different role in taxane-treated patients. Taxane treatment is a protective factor for OS in AR-V7-positive patients compared to AA/E. AR-V7 may be an effective biomarker for treatment prognosis in mCRPC patients.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2021)