How To Quantify a Genetic Firewall? A Polarity‐Based Metric for Genetic Code Engineering

3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function

(2020) Nicolás Campolo et al.   Essays in Biochemistry

Linking Engineered Cells to Their Digital Twins: A Version Control System for Strain Engineering

(2020) Jonathan Tellechea-Luzardo et al.   ACS Synthetic Biology

Xenobiology: A Journey towards Parallel Life Forms

(2020) Nediljko Budisa et al.   CHEMBIOCHEM

The long journey towards standards for engineering biosystems

(2020) Jacob Beal et al.   EMBO REPORTS

Genetic‐Code‐Expansion Strategies for Vaccine Development

(2020) Jelle A. Fok et al.   CHEMBIOCHEM

Semisynthesis of an Active Enzyme by Quantitative Click Ligation

(2019) Christian Kofoed et al.   BIOCONJUGATE CHEMISTRY

Total synthesis of Escherichia coli with a recoded genome

(2019) Julius Fredens et al.   NATURE

A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids

(2019) Sebastian Arangundy-Franklin et al.   Nature Chemistry

Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor

(2019) Elena Eremeeva et al.   NUCLEIC ACIDS RESEARCH

A metric space for semantic containment: Towards the implementation of genetic firewalls

(2019) Markus Schmidt   BIOSYSTEMS

Orthogonal Genetic Systems

(2019) John C. Chaput et al.   CHEMBIOCHEM

Anticipating alien cells with alternative genetic codes: away from the alanine world!

(2019) Vladimir Kubyshkin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Exploring hydrophobicity limits of polyproline helix with oligomeric octahydroindole-2-carboxylic acid

(2018) Vladimir Kubyshkin et al.   JOURNAL OF PEPTIDE SCIENCE

Next-generation biocontainment systems for engineered organisms

(2018) Jeong Wook Lee et al.   Nature Chemical Biology

Expansion of the genetic code via expansion of the genetic alphabet

(2018) Vivian T Dien et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The optimality of the standard genetic code assessed by an eight-objective evolutionary algorithm

(2018) Małgorzata Wnętrzak et al.   BMC EVOLUTIONARY BIOLOGY

Mitogenomics Reveals a Novel Genetic Code in Hemichordata

(2018) Yuanning Li et al.   Genome Biology and Evolution

Each of 3,323 metabolic innovations in the evolution of E. coli arose through the horizontal transfer of a single DNA segment

(2018) Tin Yau Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation

(2017) Seth A. Lieblich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional horizontal gene transfer from bacteria to eukaryotes

(2017) Filip Husnik et al.   NATURE REVIEWS MICROBIOLOGY

A semisynthetic organism engineered for the stable expansion of the genetic alphabet

(2017) Yorke Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Refactoring the Genetic Code for Increased Evolvability

(2017) Gur Pines et al.   mBio

Design Automation in Synthetic Biology

(2017) Evan Appleton et al.   Cold Spring Harbor Perspectives in Biology

The Multiple Origins of the Hydrophobicity of Fluorinated Apolar Amino Acids

(2017) João Ramiro Robalo et al.   Chem

Synthetic bugs on the loose: containment options for deeply engineered (micro)organisms

(2016) Markus Schmidt et al.   CURRENT OPINION IN BIOTECHNOLOGY

Toxicity of canavanine in tomato (Solanum lycopersicum L.) roots is due to alterations in RNS, ROS and auxin levels

(2016) Urszula Krasuska et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Design, synthesis, and testing toward a 57-codon genome

(2016) N. Ostrov et al.   SCIENCE

Xenomicrobiology: a roadmap for genetic code engineering

(2016) Carlos G. Acevedo-Rocha et al.   Microbial Biotechnology

Chemical Evolution of a Bacterial Proteome

(2015) Michael Georg Hoesl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A multiobjective approach to the genetic code adaptability problem

(2015) Lariza Laura de Oliveira et al.   BMC BIOINFORMATICS

Recoded organisms engineered to depend on synthetic amino acids

(2015) Alexis J. Rovner et al.   NATURE

Biocontainment of genetically modified organisms by synthetic protein design

(2015) Daniel J. Mandell et al.   NATURE

Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog

(2015) Daniel T Rogerson et al.   Nature Chemical Biology

Horizontal gene transfer: building the web of life

(2015) Shannon M. Soucy et al.   NATURE REVIEWS GENETICS

The structural diversity of artificial genetic polymers

(2015) Irina Anosova et al.   NUCLEIC ACIDS RESEARCH

Reassignment of a rare sense codon to a non-canonical amino acid inEscherichia coli

(2015) Takahito Mukai et al.   NUCLEIC ACIDS RESEARCH

Exploring the potential impact of an expanded genetic code on protein function

(2015) Han Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Designing logical codon reassignment – Expanding the chemistry in biology

(2015) Anaëlle Dumas et al.   Chemical Science

Robust production of recombinant phosphoproteins using cell-free protein synthesis

(2015) Javin P. Oza et al.   Nature Communications

Xenobiology, New-to-Nature Synthetic Cells and Genetic Firewall

(2014) Nediljko Budisa   CURRENT ORGANIC CHEMISTRY

Mutations Enabling Displacement of Tryptophan by 4-Fluorotryptophan as a Canonical Amino Acid of the Genetic Code

(2014) Allen Chi-Shing Yu et al.   Genome Biology and Evolution

Coupling Bioorthogonal Chemistries with Artificial Metabolism: Intracellular Biosynthesis of Azidohomoalanine and Its Incorporation into Recombinant Proteins

(2014) Ying Ma et al.   MOLECULES

Congeneric bio-adhesive mussel foot proteins designed by modified prolines revealed a chiral bias in unnatural translation

(2012) Maud Larregola et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Emerging World of Synthetic Genetics

(2012) John C. Chaput et al.   CHEMISTRY & BIOLOGY

Synthetic constructs in/for the environment: Managing the interplay between natural and engineered Biology

(2012) Markus Schmidt et al.   FEBS LETTERS

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

On the Road towards Chemically Modified Organisms Endowed with a Genetic Firewall

(2011) Carlos G. Acevedo-Rocha et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simulated evolution applied to study the genetic code optimality using a model of codon reassignments

(2011) José Santos et al.   BMC BIOINFORMATICS

Antibiotic resistance gene spread due to manure application on agricultural fields

(2011) Holger Heuer et al.   CURRENT OPINION IN MICROBIOLOGY

Expanding the Genetic Code of Escherichia coli with Phosphoserine

(2011) H.-S. Park et al.   SCIENCE

How Many Species Are There on Earth and in the Ocean?

(2011) Camilo Mora et al.   PLOS BIOLOGY

Xenobiology: A new form of life as the ultimate biosafety tool

(2010) Markus Schmidt   BIOESSAYS

Horizontal gene transfer and the genomics of enterococcal antibiotic resistance

(2010) Kelli L Palmer et al.   CURRENT OPINION IN MICROBIOLOGY

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

(2010) Heinz Neumann et al.   NATURE

Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids

(2009) Piet Herdewijn et al.   CHEMISTRY & BIODIVERSITY