P53 induces senescence in the unstable progeny of aneuploid cells

Context is everything: aneuploidy in cancer

(2019) Uri Ben-David et al.   NATURE REVIEWS GENETICS

Cancer: a CINful evolution

(2018) Altea Targa et al.   CURRENT OPINION IN CELL BIOLOGY

Determinants and clinical implications of chromosomal instability in cancer

(2018) Laurent Sansregret et al.   Nature Reviews Clinical Oncology

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

(2017) Teresa Davoli et al.   SCIENCE

APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability

(2017) Laurent Sansregret et al.   Cancer Discovery

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies

(2017) Mar Soto et al.   Cell Reports

Chromosome missegregation during anaphase triggers p53 cell cycle arrest through histone H3.3 Ser31 phosphorylation

(2016) Edward H. Hinchcliffe et al.   NATURE CELL BIOLOGY

The presence of extra chromosomes leads to genomic instability

(2016) Verena Passerini et al.   Nature Communications

The Role of Aneuploidy in Cancer Evolution

(2016) Laurent Sansregret et al.   Cold Spring Harbor Perspectives in Medicine

Short- and long-term effects of chromosome mis-segregation and aneuploidy

(2015) Stefano Santaguida et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromosome mis-segregation and cytokinesis failure in trisomic human cells

(2015) Joshua M Nicholson et al.   eLife

Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos

(2013) Tamara A. Potapova et al.   CANCER AND METASTASIS REVIEWS

Whole chromosome aneuploidy: Big mutations drive adaptation by phenotypic leap

(2012) Guangbo Chen et al.   BIOESSAYS

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Karyotypic Determinants of Chromosome Instability in Aneuploid Budding Yeast

(2012) Jin Zhu et al.   PLoS Genetics

Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

(2011) A. Janssen et al.   SCIENCE

Aneuploidy Drives Genomic Instability in Yeast

(2011) J. M. Sheltzer et al.   SCIENCE

Prolonged Prometaphase Blocks Daughter Cell Proliferation Despite Normal Completion of Mitosis

(2010) Yumi Uetake et al.   CURRENT BIOLOGY

Dr Jekyll and Mr Hyde: role of aneuploidy in cellular adaptation and cancer

(2010) Norman Pavelka et al.   CURRENT OPINION IN CELL BIOLOGY

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

(2010) Stefano Santaguida et al.   JOURNAL OF CELL BIOLOGY

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

(2010) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA