Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis
出版年份 2020 全文链接
标题
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis
作者
关键词
SARS-CoV-2, replication and transcription complex, nsp9, cap, mRNA synthesis, cryo-EM
出版物
CELL
Volume 184, Issue 1, Pages 184-193.e10
出版商
Elsevier BV
发表日期
2020-11-15
DOI
10.1016/j.cell.2020.11.016
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
- (2020) Jasper Fuk-Woo Chan et al. LANCET
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- A novel coronavirus outbreak of global health concern
- (2020) Chen Wang et al. LANCET
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural basis for RNA replication by the SARS-CoV-2 polymerase
- (2020) Quan Wang et al. CELL
- Structure of replicating SARS-CoV-2 polymerase
- (2020) Hauke S. Hillen et al. NATURE
- Structure of the RNA-dependent RNA polymerase from COVID-19 virus
- (2020) Yan Gao et al. SCIENCE
- Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex
- (2020) James Chen et al. CELL
- Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9
- (2020) Dene R. Littler et al. iScience
- Architecture of a SARS-CoV-2 mini replication and transcription complex
- (2020) Liming Yan et al. Nature Communications
- Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
- (2018) Jithesh Kottur et al. NUCLEIC ACIDS RESEARCH
- Protein AMPylation by an Evolutionarily Conserved Pseudokinase
- (2018) Anju Sreelatha et al. CELL
- New tools for the analysis and validation of cryo-EM maps and atomic models
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses
- (2015) Kathleen C. Lehmann et al. NUCLEIC ACIDS RESEARCH
- Phosphate analogues in the dissection of mechanism
- (2014) Heidi J Korhonen et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP
- (2013) Xu Jin et al. VIRUS RESEARCH
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Identification of the Inorganic Pyrophosphate Metabolizing, ATP Substituting Pathway in Mammalian Spermatozoa
- (2012) Young-Joo Yi et al. PLoS One
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
- (2010) Stephane Daffis et al. NATURE
- In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
- (2010) Mickaël Bouvet et al. PLoS Pathogens
- Severe Acute Respiratory Syndrome Coronavirus nsp9 Dimerization Is Essential for Efficient Viral Growth
- (2009) Z. J. Miknis et al. JOURNAL OF VIROLOGY
- Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase
- (2009) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2'O)-Methyltransferase Activity
- (2008) E. Decroly et al. JOURNAL OF VIROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now