Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

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Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

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Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China

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Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients

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Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact

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(2020) Vincent J. Munster et al.   NATURE

CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

(2020) Justin Harper et al.   NATURE MEDICINE

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

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DNA vaccine protection against SARS-CoV-2 in rhesus macaques

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Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

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Severe COVID-19 is marked by a dysregulated myeloid cell compartment

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Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

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Use of Baricitinib in Patients with Moderate and Severe COVID-19

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

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COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

(2020) Robert Lorenz Chua et al.   NATURE BIOTECHNOLOGY

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

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Comprehensive mapping of immune perturbations associated with severe COVID-19

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3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope–specific plasma cells and humoral immunity in nonhuman primates

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Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

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A dynamic COVID-19 immune signature includes associations with poor prognosis

(2020) Adam G. Laing et al.   NATURE MEDICINE

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

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DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

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Comprehensive Integration of Single-Cell Data

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Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence

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Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host

(2018) David Palesch et al.   NATURE

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication

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CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

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Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways

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Influenza A and methicillin-resistant Staphylococcus aureus co-infection in rhesus macaques – A model of severe pneumonia

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Complex heatmaps reveal patterns and correlations in multidimensional genomic data

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Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

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Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate

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Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

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STAR: ultrafast universal RNA-seq aligner

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Immune Signaling by RIG-I-like Receptors

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