ONO‐7684 a novel oral FXIa inhibitor: Safety, tolerability, pharmacokinetics and pharmacodynamics in a first‐in‐human study

Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty

(2020) Jeffrey I. Weitz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans

(2019) Alexander W. Koch et al.   BLOOD

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

(2019) Christina U. Lorentz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

(2019) Stephen P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects

(2018) Vidya Perera et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Global Burden of Thrombosis: Table.

(2016) Aaron M. Wendelboe et al.   CIRCULATION RESEARCH

Why factor XI deficiency is a clinical concern

(2016) Allison P. Wheeler et al.   Expert Review of Hematology

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

(2015) Harry R. Büller et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare bleeding disorders - bleeding assessment tools, laboratory aspects and phenotype and therapy of FXI deficiency

(2014) P. James et al.   HAEMOPHILIA

New Oral Anticoagulants: Comparative Pharmacology with Vitamin K Antagonists

(2013) Francesco Scaglione   CLINICAL PHARMACOKINETICS

Oral anticoagulant-associated intracerebral hemorrhage

(2011) Álvaro Cervera et al.   JOURNAL OF NEUROLOGY

Inhibition of Factor XIa as a New Approach to Anticoagulation

(2010) William A. Schumacher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Coagulation factor XI as a novel target for antithrombotic treatment

(2010) E. C. LÖWENBERG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS