Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

标题
Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors
作者
关键词
Phenstatin based indole-linked chalcones, In vitro, cell cytotoxicity, Cancer stem- like cells, Spheroid assay, Oral cancer xenograft model, PET-CT imaging, F-fluorodeoxyglucose uptake, Glucose metabolism, In silico, analysis, Molecular docking, Tubulin polymerization inhibition, Surface Plasmon Resonance, Multi-target metabolic inhibitor, Anti-cancer efficacy, Immunofluorescence, Laser confocal microscopy, Transmission electron microscopy
出版物
BIOORGANIC CHEMISTRY
Volume 105, Issue -, Pages 104447
出版商
Elsevier BV
发表日期
2020-11-01
DOI
10.1016/j.bioorg.2020.104447

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