Cancer-specific drug-drug nanoparticles of pro-apoptotic and cathepsin B-cleavable peptide-conjugated doxorubicin for drug-resistant cancer therapy

Immunomodulatory Lipocomplex Functionalized with Photosensitizer-Embedded Cancer Cell Membrane Inhibits Tumor Growth and Metastasis

(2019) Han Young Kim et al.   NANO LETTERS

Visible light-induced apoptosis activatable nanoparticles of photosensitizer-DEVD-anticancer drug conjugate for targeted cancer therapy

(2019) Wooram Um et al.   BIOMATERIALS

Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System

(2018) Noam Brown et al.   ACS Nano

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker

(2018) Dharmini Mehta et al.   MOLECULAR PHARMACEUTICS

Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation

(2018) Miles A. Miller et al.   ACS Nano

Carrier-free nanoparticles of cathepsin B-cleavable peptide-conjugated doxorubicin prodrug for cancer targeting therapy

(2018) Man Kyu Shim et al.   JOURNAL OF CONTROLLED RELEASE

Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma

(2017) Shawn T. Beug et al.   Nature Communications

Cathepsin B-Specific Metabolic Precursor for In Vivo Tumor-Specific Fluorescence Imaging

(2016) Man Kyu Shim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New insights and evolving role of pegylated liposomal doxorubicin in cancer therapy

(2016) Alberto A. Gabizon et al.   DRUG RESISTANCE UPDATES

Does Nanomedicine Have a Delivery Problem?

(2016) Michael Torrice   ACS Central Science

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Synthesis of a novel, sequentially active-targeted drug delivery nanoplatform for breast cancer therapy

(2015) Arpan Satsangi et al.   BIOMATERIALS

Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorated gold nanoparticles

(2015) Shaobo Ruan et al.   BIOMATERIALS

Promises and Challenges of Smac Mimetics as Cancer Therapeutics

(2015) S. Fulda   CLINICAL CANCER RESEARCH

The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine

(2015) Silvia Marchesan et al.   MOLECULES

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Body fat composition impacts the hematologic toxicities and pharmacokinetics of doxorubicin in Asian breast cancer patients

(2014) A. L. Wong et al.   BREAST CANCER RESEARCH AND TREATMENT

Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy

(2014) Woonyoung Choi et al.   CANCER CELL

Self-Assembly of Phenylalanine-Based Molecules

(2014) Helen W. German et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides

(2013) Wei Gao et al.   BIOMATERIALS

Cathepsin B as a cancer target

(2013) Christopher S Gondi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Tumor-targeting multi-functional nanoparticles for theragnosis: New paradigm for cancer therapy

(2012) Ju Hee Ryu et al.   ADVANCED DRUG DELIVERY REVIEWS

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Targeting IAP proteins for therapeutic intervention in cancer

(2012) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Multicenter Phase II Trial of Temozolomide in Mycosis Fungoides/Sezary Syndrome: Correlation with O6-Methylguanine-DNA Methyltransferase and Mismatch Repair Proteins

(2011) C. Querfeld et al.   CLINICAL CANCER RESEARCH

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance

(2009) Yogesh Patil et al.   JOURNAL OF CONTROLLED RELEASE

WL-276, an Antagonist against Bcl-2 Proteins, Overcomes Drug Resistance and Suppresses Prostate Tumor Growth

(2008) L. Wang et al.   CANCER RESEARCH

A History of Cancer Chemotherapy

(2008) Vincent T. DeVita et al.   CANCER RESEARCH